{"id":3677,"date":"2019-02-01T12:28:54","date_gmt":"2019-02-01T05:28:54","guid":{"rendered":"https:\/\/pharmog.com\/wp\/?p=3677"},"modified":"2025-01-08T22:27:58","modified_gmt":"2025-01-08T15:27:58","slug":"terlipressin","status":"publish","type":"post","link":"https:\/\/pharmog.com\/wp\/terlipressin\/","title":{"rendered":"Terlipressin"},"content":{"rendered":"<p><em>Thu\u1ed1c Terlipressin l\u00e0 thu\u1ed1c g\u00ec ? D\u01b0\u1edbi \u0111\u00e2y l\u00e0 n\u1ed9i dung t\u1edd h\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng g\u1ed1c c\u1ee7a Thu\u1ed1c Terlipressin (Th\u00f4ng tin bao g\u1ed3m li\u1ec1u d\u00f9ng, c\u00e1ch d\u00f9ng, ch\u1ec9 \u0111\u1ecbnh, ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh, th\u1eadn tr\u1ecdng, d\u01b0\u1ee3c l\u00fd&#8230;)<\/em><\/p><div id=\"ez-toc-container\" class=\"ez-toc-v2_0_81 ez-toc-wrap-left counter-hierarchy ez-toc-counter ez-toc-white ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">N\u1ed9i dung ch\u00ednh<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 eztoc-toggle-hide-by-default' ><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/pharmog.com\/wp\/terlipressin\/#1-ten-hoat-chat-va-biet-duoc\" >1. T\u00ean ho\u1ea1t ch\u1ea5t v\u00e0 bi\u1ec7t d\u01b0\u1ee3c:<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/pharmog.com\/wp\/terlipressin\/#2-dang-bao-che-%e2%80%93-ham-luong\" >2. D\u1ea1ng b\u00e0o ch\u1ebf &#8211; H\u00e0m l\u01b0\u1ee3ng:<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/pharmog.com\/wp\/terlipressin\/#3-video-by-pharmog\" >3. Video by Pharmog:<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/pharmog.com\/wp\/terlipressin\/#4-ung-dung-lam-sang\" >4. \u1ee8ng d\u1ee5ng l\u00e2m s\u00e0ng:<\/a><ul class='ez-toc-list-level-2' ><li class='ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/pharmog.com\/wp\/terlipressin\/#41-chi-dinh\" >4.1. Ch\u1ec9 \u0111\u1ecbnh:<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/pharmog.com\/wp\/terlipressin\/#42-lieu-dung-%e2%80%93-cach-dung\" >4.2. Li\u1ec1u d\u00f9ng &#8211; C\u00e1ch d\u00f9ng:<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/pharmog.com\/wp\/terlipressin\/#43-chong-chi-dinh\" >4.3. Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh:<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/pharmog.com\/wp\/terlipressin\/#44-than-trong\" >4.4 Th\u1eadn tr\u1ecdng:<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-9\" href=\"https:\/\/pharmog.com\/wp\/terlipressin\/#45-su-dung-cho-phu-nu-co-thai-va-cho-con-bu\" >4.5 S\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa:<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-10\" href=\"https:\/\/pharmog.com\/wp\/terlipressin\/#46-tac-dung-khong-mong-muon-adr\" >4.6 T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n (ADR):<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-11\" href=\"https:\/\/pharmog.com\/wp\/terlipressin\/#47-huong-dan-cach-xu-tri-adr\" >4.7 H\u01b0\u1edbng d\u1eabn c\u00e1ch x\u1eed tr\u00ed ADR:<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-12\" href=\"https:\/\/pharmog.com\/wp\/terlipressin\/#48-tuong-tac-voi-cac-thuoc-khac\" >4.8 T\u01b0\u01a1ng t\u00e1c v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1c:<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-13\" href=\"https:\/\/pharmog.com\/wp\/terlipressin\/#49-qua-lieu-va-xu-tri\" >4.9 Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed:<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-14\" href=\"https:\/\/pharmog.com\/wp\/terlipressin\/#5-co-che-tac-dung-cua-thuoc\" >5. C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c :<\/a><ul class='ez-toc-list-level-2' ><li class='ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-15\" href=\"https:\/\/pharmog.com\/wp\/terlipressin\/#51-duoc-luc-hoc\" >5.1. D\u01b0\u1ee3c l\u1ef1c h\u1ecdc:<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-16\" href=\"https:\/\/pharmog.com\/wp\/terlipressin\/#52-duoc-dong-hoc\" >5.2. D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc:<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-17\" href=\"https:\/\/pharmog.com\/wp\/terlipressin\/#53-giai-thich\" >5.3 Gi\u1ea3i th\u00edch:<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-18\" href=\"https:\/\/pharmog.com\/wp\/terlipressin\/#54-thay-the-thuoc\" >5.4 Thay th\u1ebf thu\u1ed1c :<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-19\" href=\"https:\/\/pharmog.com\/wp\/terlipressin\/#6-phan-thong-tin-kem-theo-cua-thuoc\" >6. Ph\u1ea7n th\u00f4ng tin k\u00e8m theo c\u1ee7a thu\u1ed1c:<\/a><ul class='ez-toc-list-level-2' ><li class='ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-20\" href=\"https:\/\/pharmog.com\/wp\/terlipressin\/#61-danh-muc-ta-duoc\" >6.1. Danh m\u1ee5c t\u00e1 d\u01b0\u1ee3c:<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-21\" href=\"https:\/\/pharmog.com\/wp\/terlipressin\/#62-tuong-ky\" >6.2. T\u01b0\u01a1ng k\u1ef5 :<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-22\" href=\"https:\/\/pharmog.com\/wp\/terlipressin\/#63-bao-quan\" >6.3. B\u1ea3o qu\u1ea3n:<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-23\" href=\"https:\/\/pharmog.com\/wp\/terlipressin\/#64-thong-tin-khac\" >6.4. Th\u00f4ng tin kh\u00e1c :<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-24\" href=\"https:\/\/pharmog.com\/wp\/terlipressin\/#65-tai-lieu-tham-khao\" >6.5 T\u00e0i li\u1ec7u tham kh\u1ea3o:<\/a><\/li><\/ul><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-25\" href=\"https:\/\/pharmog.com\/wp\/terlipressin\/#7-nguoi-dang-tai-tac-gia\" >7. Ng\u01b0\u1eddi \u0111\u0103ng t\u1ea3i \/T\u00e1c gi\u1ea3:<\/a><\/li><\/ul><\/nav><\/div>\n\n<h1><span class=\"ez-toc-section\" id=\"1-ten-hoat-chat-va-biet-duoc\"><\/span>1. T\u00ean ho\u1ea1t ch\u1ea5t v\u00e0 bi\u1ec7t d\u01b0\u1ee3c:<span class=\"ez-toc-section-end\"><\/span><\/h1>\n<p><strong><em>Ho\u1ea1t ch\u1ea5t :<\/em> <\/strong><a href=\"https:\/\/pharmog.com\/wp\/terlipressin\/\"><strong>Terlipressin acetate\u00a0<\/strong><\/a><\/p>\n<p><strong><em>Ph\u00e2n lo\u1ea1i: <\/em><\/strong><em>Thu\u1ed1c co m\u1ea1ch.<\/em> <em>Thu\u1ed1c c\u1ea7m m\u00e1u.<\/em> <em>Hormon th\u00f9y sau tuy\u1ebfn y\u00ean ADH<\/em><\/p>\n<p><strong><em>Nh\u00f3m<\/em><\/strong> <strong><em>ph\u00e1p l\u00fd: <\/em><\/strong><em>Thu\u1ed1c k\u00ea \u0111\u01a1n ETC \u2013 (Ethical drugs, prescription drugs, Prescription only medicine)<\/em><\/p>\n<p><strong><em>M\u00e3 ATC<\/em><\/strong> (Anatomical Therapeutic Chemical): H01B A04.<\/p>\n<p><strong>Brand name:<\/strong><\/p>\n<p><strong>Generic <\/strong>: Terlipressin, <a href=\"https:\/\/pharmog.com\/wp\/terlipressin-glypressin\/\">Glypressin<\/a>, Remestyp<br \/>\n<script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-5528370293090692\" crossorigin=\"anonymous\"><\/script> <ins class=\"adsbygoogle\" style=\"display: block; text-align: center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-5528370293090692\" data-ad-slot=\"8909623906\"><\/ins> <script> (adsbygoogle = window.adsbygoogle || []).push({}); <\/script><\/p>\n<h1><span class=\"ez-toc-section\" id=\"2-dang-bao-che-%e2%80%93-ham-luong\"><\/span>2. D\u1ea1ng b\u00e0o ch\u1ebf &#8211; H\u00e0m l\u01b0\u1ee3ng:<span class=\"ez-toc-section-end\"><\/span><\/h1>\n<p><strong><em>D\u1ea1ng thu\u1ed1c v\u00e0 h\u00e0m l\u01b0\u1ee3ng<\/em><\/strong><\/p>\n<p>B\u1ed9t \u0111\u00f4ng kh\u00f4 pha ti\u00eam 1mg<\/p>\n<p>Dung d\u1ecbch ti\u00eam 0,2mg\/ml<\/p>\n<p><strong><em>Thu\u1ed1c tham kh\u1ea3o:<\/em><\/strong><\/p>\n<table>\n<tbody>\n<tr>\n<td colspan=\"2\"><strong><em>TERLIPRESSIN 0.2mg\/ml<\/em><\/strong><\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\"><em>M\u1ed7i \u1ed1ng ti\u00eam 5ml c\u00f3 ch\u1ee9a:<\/em><\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td>Terlipressin acetat<\/td>\n<td>&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.<\/td>\n<td>1 mg<\/td>\n<\/tr>\n<tr>\n<td>T\u00e1 d\u01b0\u1ee3c<\/td>\n<td>&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.<\/td>\n<td>v\u1eeba \u0111\u1ee7 (Xem m\u1ee5c 6.1)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><img loading=\"lazy\" decoding=\"async\" width=\"657\" height=\"307\" class=\"wp-image-36191\" src=\"https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2019\/02\/word-image-60.png\" srcset=\"https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2019\/02\/word-image-60.png 657w, https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2019\/02\/word-image-60-300x140.png 300w\" sizes=\"auto, (max-width: 657px) 100vw, 657px\" \/><\/p>\n<h1><span class=\"ez-toc-section\" id=\"3-video-by-pharmog\"><\/span>3. Video by Pharmog:<span class=\"ez-toc-section-end\"><\/span><\/h1>\n<p><strong>[VIDEO D\u01af\u1ee2C L\u00dd]<\/strong><\/p>\n<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<\/p>\n<p>\u25ba K\u1ecbch B\u1ea3n: PharmogTeam<\/p>\n<p>\u25ba Youtube: https:\/\/www.youtube.com\/c\/pharmog<\/p>\n<p>\u25ba Facebook: https:\/\/www.facebook.com\/pharmog\/<\/p>\n<p>\u25ba Group : H\u1ed9i nh\u1eefng ng\u01b0\u1eddi m\u00ea d\u01b0\u1ee3c l\u00fd<\/p>\n<p>\u25ba Instagram : https:\/\/www.instagram.com\/pharmogvn\/<\/p>\n<p>\u25ba Website: pharmog.com<\/p>\n<h1><span class=\"ez-toc-section\" id=\"4-ung-dung-lam-sang\"><\/span>4. \u1ee8ng d\u1ee5ng l\u00e2m s\u00e0ng:<span class=\"ez-toc-section-end\"><\/span><\/h1>\n<h2><span class=\"ez-toc-section\" id=\"41-chi-dinh\"><\/span>4.1. Ch\u1ec9 \u0111\u1ecbnh:<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Gi\u00e3n t\u0129nh m\u1ea1ch th\u1ef1c qu\u1ea3n xu\u1ea5t huy\u1ebft.<\/p>\n<p>\u0110i\u1ec1u tr\u1ecb h\u1ed9i ch\u1ee9ng gan th\u1eadn \u0111\u1ed9 1, \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n b\u1edfi s\u1ef1 suy gi\u1ea3m ch\u1ee9c n\u0103ng th\u1eadn c\u1ea5p t\u00ednh t\u1ef1 ph\u00e1t, \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n b\u1ecb b\u1ec7nh x\u01a1 gan c\u1ed5 tr\u01b0\u1edbng n\u1eb7ng.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"42-lieu-dung-%e2%80%93-cach-dung\"><\/span>4.2. Li\u1ec1u d\u00f9ng &#8211; C\u00e1ch d\u00f9ng:<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><strong><em>C\u00e1ch d\u00f9ng<\/em><\/strong> :<\/p>\n<p>\u0110\u01b0\u1eddng d\u00f9ng: Ti\u00eam t\u0129nh m\u1ea1ch.<\/p>\n<p><strong><em>Li\u1ec1u d\u00f9ng:<\/em><\/strong><\/p>\n<p><em>Gi\u00e3n t\u0129nh m\u1ea1ch th\u1ef1c qu\u1ea3n xu\u1ea5t huy\u1ebft:<\/em><\/p>\n<p>Ng\u01b0\u1eddi l\u1edbn: Ti\u00eam t\u0129nh m\u1ea1ch li\u1ec1u kh\u1edfi \u0111\u1ea7u 2 mg terlipressin acetat m\u1ed7i 4 gi\u1edd. N\u00ean duy tr\u00ec \u0111i\u1ec1u tr\u1ecb cho \u0111\u1ebfn khi ki\u1ec3m so\u00e1t \u0111\u01b0\u1ee3c vi\u1ec7c xu\u1ea5t huy\u1ebft trong 24 gi\u1edd, c\u00f3 th\u1ec3 t\u1ed1i \u0111a \u0111\u1ebfn 48 gi\u1edd. Sau li\u1ec1u kh\u1edfi \u0111\u1ea7u, \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u xu\u1ed1ng c\u00f2n 1 mg ti\u00eam t\u0129nh m\u1ea1ch m\u1ed7i 4 gi\u1edd \u1edf b\u1ec7nh nh\u00e2n c\u00f3 c\u00e2n n\u1eb7ng &lt; 50kg ho\u1eb7c n\u1ebfu c\u00f3 t\u00e1c d\u1ee5ng ph\u1ee5 x\u1ea3y ra.<\/p>\n<p>C\u00f4ng b\u1ed1 t\u1eeb h\u1ed9i ngh\u1ecb Braveno l\u1ea7n th\u1ee9 15 \u0111\u00e3 khuy\u1ebfn c\u00e1o th\u1eddi gian \u0111i\u1ec1u tr\u1ecb \u0111\u1ebfn 5 ng\u00e0y.<\/p>\n<p><em>H\u1ed9i ch\u1ee9ng gan th\u1eadn \u0111\u1ed9 1<\/em>: 3-4 mg terlipressin acetat m\u1ed7i 24 gi\u1edd \u0111\u01b0\u1ee3c chia l\u00e0m 3 ho\u1eb7c 4 l\u1ea7n ti\u00eam.<\/p>\n<p>Trong tr\u01b0\u1eddng h\u1ee3p kh\u00f4ng c\u00f3 b\u1ea5t k\u1ef3 s\u1ef1 suy gi\u1ea3m creatinin huy\u1ebft t\u01b0\u01a1ng sau 3 ng\u00e0y \u0111i\u1ec1u tr\u1ecb, khuy\u1ebfn c\u00e1o n\u00ean ng\u01b0ng \u0111i\u1ec1u tr\u1ecb v\u1edbi Terlipressin.<\/p>\n<p>Trong tr\u01b0\u1eddng h\u1ee3p kh\u00e1c, \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Terlipressin \u0111\u01b0\u1ee3c ti\u1ebfp t\u1ee5c cho \u0111\u1ebfn khi ghi nh\u1eadn \u0111\u01b0\u1ee3c n\u1ed3ng \u0111\u1ed9 creatinin huy\u1ebft t\u01b0\u01a1ng &lt; 130\u00b5mol\/L ho\u1eb7c creatinin huy\u1ebft t\u01b0\u01a1ng gi\u1ea3m \u00edt nh\u1ea5t 30% so v\u1edbi gi\u00e1 tr\u1ecb \u0111\u01b0\u1ee3c \u0111o t\u1ea1i th\u1eddi \u0111i\u1ec3m ch\u1ea9n \u0111o\u00e1n h\u1ed9i ch\u1ee9ng gan th\u1eadn.<\/p>\n<p>Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb trung b\u00ecnh chu\u1ea9n l\u00e0 10 ng\u00e0y.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"43-chong-chi-dinh\"><\/span>4.3. Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh:<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh \u1edf ph\u1ee5 n\u1eef mang thai.<\/p>\n<p>Qu\u00e1 m\u1eabn v\u1edbi terlipressin ho\u1eb7c b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n t\u00e1 d\u01b0\u1ee3c n\u00e0o c\u1ee7a thu\u1ed1c.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"44-than-trong\"><\/span>4.4 Th\u1eadn tr\u1ecdng:<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Huy\u1ebft \u00e1p, nh\u1ecbp tim v\u00e0 c\u00e2n b\u1eb1ng d\u1ecbch n\u00ean \u0111\u01b0\u1ee3c theo d\u00f5i trong th\u1eddi gian \u0111i\u1ec1u tr\u1ecb. \u0110\u1ec3 tr\u00e1nh ho\u1ea1i t\u1eed khu tr\u00fa t\u1ea1i v\u1ecb tr\u00ed ti\u00eam, ph\u1ea3i ti\u00eam t\u0129nh m\u1ea1ch.<\/p>\n<p>C\u1ea7n th\u1eadn tr\u1ecdng khi \u0111i\u1ec1u tr\u1ecb \u1edf c\u00e1c b\u1ec7nh nh\u00e2n b\u1ecb t\u0103ng huy\u1ebft \u00e1p ho\u1eb7c \u0111\u00e3 ghi nh\u1eadn c\u00f3 b\u1ec7nh tim. Kh\u00f4ng n\u00ean d\u00f9ng terlipressin \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n b\u1ecb s\u1ed1c nhi\u1ec5m tr\u00f9ng c\u00f3 cung l\u01b0\u1ee3ng tim th\u1ea5p.<\/p>\n<p>Tr\u1ebb em v\u00e0 ng\u01b0\u1eddi cao tu\u1ed5i: N\u00ean th\u1eadn tr\u1ecdng \u0111\u1eb7c bi\u1ec7t khi \u0111i\u1ec1u tr\u1ecb \u1edf tr\u1ebb em v\u00e0 ng\u01b0\u1eddi cao tu\u1ed5i, v\u00ec kinh nghi\u1ec7m \u1edf nh\u00f3m ng\u01b0\u1eddi n\u00e0y c\u00f2n h\u1ea1n ch\u1ebf.<\/p>\n<p>Ch\u01b0a c\u00f3 d\u1eef li\u1ec7u li\u00ean quan \u0111\u1ebfn li\u1ec1u khuy\u1ebfn c\u00e1o \u1edf nh\u1eefng nh\u00f3m \u0111\u1ed1i t\u01b0\u1ee3ng \u0111\u1eb7c bi\u1ec7t n\u00e0y.<\/p>\n<p><strong>T\u00e1c \u0111\u1ed9ng c\u1ee7a thu\u1ed1c tr\u00ean ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/strong><\/p>\n<p>Ch\u01b0a c\u00f3 nghi\u00ean c\u1ee9u \u0111\u01b0\u1ee3c thi\u1ebft l\u1eadp v\u1ec1 t\u00e1c \u0111\u1ed9ng c\u1ee7a thu\u1ed1c l\u00ean kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c. C\u1ea7n th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng cho c\u00e1c \u0111\u1ed1i t\u01b0\u1ee3ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<br \/>\n<script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-5528370293090692\" crossorigin=\"anonymous\"><\/script> <ins class=\"adsbygoogle\" style=\"display: block; text-align: center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-5528370293090692\" data-ad-slot=\"8909623906\"><\/ins> <script> (adsbygoogle = window.adsbygoogle || []).push({}); <\/script><\/p>\n<h2><span class=\"ez-toc-section\" id=\"45-su-dung-cho-phu-nu-co-thai-va-cho-con-bu\"><\/span>4.5 S\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa:<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><em>X\u1ebfp h\u1ea1ng c\u1ea3nh b\u00e1o<\/em><\/p>\n<p>AU TGA pregnancy category: D<\/p>\n<p>US FDA pregnancy category: NA<\/p>\n<p><em>Th\u1eddi k\u1ef3 mang thai:<\/em><\/p>\n<p>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb Terlipressin khi mang thai.<\/p>\n<p>Terlipressin cho th\u1ea5y g\u00e2y ra co th\u1eaft t\u1eed cung v\u00e0 t\u0103ng \u00e1p l\u1ef1c trong t\u1eed cung \u1edf giai \u0111o\u1ea1n \u0111\u1ea7u thai k\u1ef3 v\u00e0 c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m l\u01b0u l\u01b0\u1ee3ng m\u00e1u t\u1eed cung.<\/p>\n<p>Terlipressin c\u00f3 th\u1ec3 g\u00e2y ra t\u00e1c d\u1ee5ng c\u00f3 h\u1ea1i cho ph\u1ee5 n\u1eef mang thai v\u00e0 ph\u00f4i thai.<\/p>\n<p><em>Th\u1eddi k\u1ef3 cho con b\u00fa:<\/em><\/p>\n<p>Ch\u01b0a c\u00f3 \u0111\u1ea7y \u0111\u1ee7 th\u00f4ng tin v\u1ec1 vi\u1ec7c Terlipressin \u0111\u01b0\u1ee3c ti\u1ebft v\u00e0o s\u1eefa ng\u01b0\u1eddi m\u1eb9. Kh\u00f4ng n\u00ean d\u00f9ng Terlipressin \u1edf ph\u1ee5 n\u1eef \u0111ang trong th\u1eddi k\u1ef3 cho con b\u00fa.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"46-tac-dung-khong-mong-muon-adr\"><\/span>4.6 T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n (ADR):<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<table>\n<tbody>\n<tr>\n<td><strong>Ph\u00e2n lo\u1ea1i h\u1ec7 c\u01a1 quan<\/strong><\/td>\n<td><strong>Th\u01b0\u1eddng g\u0103p (1-10%)<\/strong><\/td>\n<td colspan=\"2\"><strong>\u00edt g\u0103p (0,1-1%)<\/strong><\/td>\n<td colspan=\"2\"><strong>Hi\u1ebfm g\u1eb7p (0,01-0,1%)<\/strong><\/td>\n<td colspan=\"2\"><strong>Ch\u01b0a bi\u1ebft (Kh\u00f4ng th\u1ec3 d\u1ef1 \u0111o\u00e1n t\u1eeb c\u00e1c d\u1ef1 li\u1ec7u s\u1eb5n c\u00f3)<\/strong><\/td>\n<\/tr>\n<tr>\n<td colspan=\"8\"><em>S\u1ef1 r\u1ed1i lo\u1ea1n<\/em><\/td>\n<\/tr>\n<tr>\n<td>Chuy\u1ec3n h\u00f3a<\/td>\n<td colspan=\"2\"><\/td>\n<td colspan=\"2\">Gi\u1ea3m natri m\u00e1u n\u1ebfu kh\u00f4ng ki\u1ec3m so\u00e1t d\u1ecbch<\/td>\n<td colspan=\"2\"><\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td>H\u1ec7 th\u1ea7n kinh<\/td>\n<td colspan=\"2\">Nh\u1ee9c \u0111\u1ea7u<\/td>\n<td colspan=\"2\"><\/td>\n<td colspan=\"2\"><\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td rowspan=\"6\">Tim<\/td>\n<td colspan=\"2\" rowspan=\"6\">Nh\u1ecbp tim ch\u1eadm<\/td>\n<td colspan=\"2\">Rung t\u00e2m nh\u0129<\/td>\n<td colspan=\"2\" rowspan=\"6\"><\/td>\n<td rowspan=\"6\">Xo\u1eafn \u0111\u1ec9nh Suy tim<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\">Lo\u1ea1n nh\u1ecbp ngo\u1ea1i t\u00e2m thu th\u1ea5t<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\">Nh\u1ecbp tim nhanh<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\">\u0110au ng\u1ef1c<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\">Nh\u1ed3i m\u00e1u c\u01a1 tim<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\">Tr\u00e0n d\u1ecbch k\u00e8m ph\u00f9 ph\u1ed5i<\/td>\n<\/tr>\n<tr>\n<td>M\u1ea1ch<\/td>\n<td colspan=\"2\">Co m\u1ea1ch ngo\u1ea1i bi\u00ean<br \/>\nThi\u1ebfu m\u00e1u ngo\u1ea1i bi\u00ean<br \/>\nM\u1eb7t xanh xao<br \/>\nT\u0103ng huy\u1ebft \u00e1p<\/td>\n<td colspan=\"2\">Thi\u1ebfu m\u00e1u ru\u1ed9t<br \/>\nXanh t\u00edm ngo\u1ea1i bi\u00ean<br \/>\nCh\u1ee9ng b\u1ed1c h\u1ecfa<\/td>\n<td colspan=\"2\"><\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td>H\u00f4 h\u1ea5p<\/td>\n<td colspan=\"2\"><\/td>\n<td colspan=\"2\">Suy li\u1ec7t h\u00f4 h\u1ea5p<br \/>\nSuy h\u00f4 h\u1ea5p<\/td>\n<td colspan=\"2\">Kh\u00f3 th\u1edf<\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td>Ti\u00eau h\u00f3a<\/td>\n<td colspan=\"2\">Chu\u1ed9t r\u00fat b\u1ee5ng ng\u1eafn h\u1ea1n<br \/>\nTi\u00eau ch\u1ea3y ng\u1eafn h\u1ea1n<\/td>\n<td colspan=\"2\">Bu\u1ed3n n\u00f4n ng\u1eafn h\u1ea1n<br \/>\nN\u00f4n ng\u1eafn h\u1ea1n<\/td>\n<td colspan=\"2\"><\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td>Da v\u00e0 d\u01b0\u1edbi da<\/td>\n<td colspan=\"2\"><\/td>\n<td colspan=\"2\"><\/td>\n<td colspan=\"2\"><\/td>\n<td>Ho\u1ea1i t\u1eed da<\/td>\n<\/tr>\n<tr>\n<td>Th\u1eddi k\u1ef3 mang thai, s\u1ea3n k\u1ef3 v\u00e0 chu sinh<\/td>\n<td colspan=\"2\"><\/td>\n<td colspan=\"2\"><\/td>\n<td colspan=\"2\"><\/td>\n<td>Co th\u1eaft t\u1eed cung<br \/>\nGi\u1ea3m l\u01b0u l\u01b0\u1ee3ng m\u00e1u nu\u00f4i t\u1eed cung<\/td>\n<\/tr>\n<tr>\n<td>To\u00e0n th\u00e2n<\/td>\n<td colspan=\"2\"><\/td>\n<td colspan=\"2\">Ho\u1ea1i t\u1eed n\u01a1i ti\u00eam<\/td>\n<td colspan=\"2\"><\/td>\n<td><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><em>Th\u00f4ng b\u00e1o cho B\u00e1c s\u0129 nh\u1eefng t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n g\u1eb7p ph\u1ea3i khi s\u1eed d\u1ee5ng thu\u1ed1c.<\/em><\/p>\n<h2><span class=\"ez-toc-section\" id=\"47-huong-dan-cach-xu-tri-adr\"><\/span>4.7 H\u01b0\u1edbng d\u1eabn c\u00e1ch x\u1eed tr\u00ed ADR:<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Ng\u1eebng s\u1eed d\u1ee5ng thu\u1ed1c. V\u1edbi c\u00e1c ph\u1ea3n \u1ee9ng b\u1ea5t l\u1ee3i nh\u1eb9, th\u01b0\u1eddng ch\u1ec9 c\u1ea7n ng\u1eebng thu\u1ed1c. Tr\u01b0\u1eddng h\u1ee3p m\u1eabn c\u1ea3m n\u1eb7ng ho\u1eb7c ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng, c\u1ea7n ti\u1ebfn h\u00e0nh \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3 (gi\u1eef tho\u00e1ng kh\u00ed v\u00e0 d\u00f9ng epinephrin, th\u1edf oxygen, d\u00f9ng kh\u00e1ng histamin, corticoid&#8230;).<\/p>\n<h2><span class=\"ez-toc-section\" id=\"48-tuong-tac-voi-cac-thuoc-khac\"><\/span>4.8 T\u01b0\u01a1ng t\u00e1c v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1c:<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Terlipressin l\u00e0m t\u0103ng t\u00e1c d\u1ee5ng h\u1ea1 huy\u1ebft \u00e1p c\u1ee7a c\u00e1c thu\u1ed1c ch\u1eb9n beta kh\u00f4ng ch\u1ecdn l\u1ecdc tr\u00ean t\u0129nh m\u1ea1ch c\u1eeda.<\/p>\n<p>D\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c thu\u1ed1c \u0111\u00e3 \u0111\u01b0\u1ee3c bi\u1ebft g\u00e2y ra nh\u1ecbp tim ch\u1eadm (nh\u01b0 propofol, sufentanil) c\u00f3 th\u1ec3 l\u00e0m ch\u1eadm nh\u1ecbp tim h\u01a1n v\u00e0 gi\u1ea3m cung l\u01b0\u1ee3ng tim. C\u00e1c t\u00e1c \u0111\u1ed9ng n\u00e0y g\u00e2y ra b\u1edfi s\u1ef1 \u1ee9c ch\u1ebf c\u00f3 ph\u1ea3n x\u1ea1 ho\u1ea1t t\u00ednh tim th\u00f4ng qua th\u1ea7n kinh ph\u1ebf v\u1ecb do huy\u1ebft \u00e1p t\u0103ng cao.<br \/>\n<script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-5528370293090692\" crossorigin=\"anonymous\"><\/script> <ins class=\"adsbygoogle\" style=\"display: block; text-align: center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-5528370293090692\" data-ad-slot=\"8909623906\"><\/ins> <script> (adsbygoogle = window.adsbygoogle || []).push({}); <\/script><\/p>\n<h2><span class=\"ez-toc-section\" id=\"49-qua-lieu-va-xu-tri\"><\/span>4.9 Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed:<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Kh\u00f4ng n\u00ean s\u1eed d\u1ee5ng qu\u00e1 li\u1ec1u khuy\u1ebfn c\u00e1o (2mg terlipressin acetat ho\u1eb7c 1,7mg terlipressin\/4 gi\u1edd) v\u00ec nguy c\u01a1 x\u1ea3y ra c\u00e1c t\u00e1c d\u1ee5ng ph\u1ee5 nghi\u00eam tr\u1ecdng ph\u1ee5 thu\u1ed9c li\u1ec1u d\u00f9ng.<\/p>\n<h1><span class=\"ez-toc-section\" id=\"5-co-che-tac-dung-cua-thuoc\"><\/span>5. C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c :<span class=\"ez-toc-section-end\"><\/span><\/h1>\n<h2><span class=\"ez-toc-section\" id=\"51-duoc-luc-hoc\"><\/span>5.1. D\u01b0\u1ee3c l\u1ef1c h\u1ecdc:<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Terlipressin l\u00e0m gi\u1ea3m t\u0103ng huy\u1ebft \u00e1p c\u1eeda, \u0111\u1ed3ng th\u1eddi l\u00e0m gi\u1ea3m tu\u1ea7n ho\u00e0n \u1edf v\u00f9ng m\u1ea1ch m\u00e1u c\u1eeda v\u00e0 l\u00e0m co th\u1eaft c\u00e1c c\u01a1 th\u1ef1c qu\u1ea3n ch\u1ecbu s\u1ef1 \u0111\u00e8 \u00e9p li\u00ean t\u1ee5c do gi\u00e3n t\u0129nh m\u1ea1ch th\u1ef1c qu\u1ea3n. Lysine-vasopressin (LVP) c\u00f3 ho\u1ea1t t\u00ednh sinh h\u1ecdc \u0111\u01b0\u1ee3c ph\u00f3ng th\u00edch k\u00e9o d\u00e0i t\u1eeb terlipressin l\u00e0 ch\u1ea5t t\u1ea1o hormon kh\u00f4ng ho\u1ea1t t\u00ednh v\u00e0 duy tr\u00ec \u1edf m\u1ed9t m\u1ee9c n\u1ed3ng \u0111\u1ed9 cao h\u01a1n hi\u1ec7u qu\u1ea3 t\u1ed1i thi\u1ec3u v\u00e0 d\u01b0\u1edbi m\u1ee9c g\u00e2y \u0111\u1ed9c qua 4-6 gi\u1edd do s\u1ef1 \u0111\u00e0o th\u1ea3i v\u1ec1 m\u1eb7t chuy\u1ec3n h\u00f3a c\u1ee7a LVP song song v\u1edbi s\u1ef1 ph\u00f3ng th\u00edch. T\u00e1c d\u1ee5ng \u0111\u1eb7c hi\u1ec7u c\u1ee7a terlipressin \u0111\u01b0\u1ee3c \u0111\u00e1nh gi\u00e1 nh\u01b0 sau:<\/p>\n<p>Li\u1ec1u 1mg v\u00e0 2mg terlipressin c\u00f3 hi\u1ec7u qu\u1ea3 l\u00e0m gi\u1ea3m \u00e1p l\u1ef1c t\u0129nh m\u1ea1ch c\u1eeda v\u00e0 g\u00e2y co m\u1ea1ch. T\u00e1c d\u1ee5ng l\u00e0m gi\u1ea3m \u00e1p l\u1ef1c t\u0129nh m\u1ea1ch c\u1eeda v\u00e0 t\u0129nh m\u1ea1ch \u0111\u01a1n ph\u1ee5 thu\u1ed9c li\u1ec1u. N\u1ebfu s\u1eed d\u1ee5ng li\u1ec1u th\u1ea5p th\u00ec hi\u1ec7u qu\u1ea3 c\u00f3 th\u1ec3 gi\u1ea3m sau 3 gi\u1edd, trong khi d\u1eef li\u1ec7u huy\u1ebft \u0111\u1ed9ng h\u1ecdc cho th\u1ea5y ch\u1ebf \u0111\u1ed9 li\u1ec1u 2mg c\u00f3 hi\u1ec7u qu\u1ea3 h\u01a1n 1mg v\u00ec ch\u1ebf \u0111\u1ed9 li\u1ec1u cao c\u00f3 th\u1ec3 t\u1ea1o ra hi\u1ec7u qu\u1ea3 \u1ed5n \u0111\u1ecbnh trong su\u1ed1t giai \u0111o\u1ea1n \u0111i\u1ec1u tr\u1ecb (4 gi\u1edd).<\/p>\n<p><em>H\u1ec7 ti\u00eau h\u00f3a:<\/em><\/p>\n<p>Terlipressin l\u00e0m t\u0103ng tr\u01b0\u01a1ng l\u1ef1c c\u1ee7a m\u1ea1ch v\u00e0 c\u00e1c t\u1ebf b\u00e0o c\u01a1 tr\u01a1n ngo\u00e0i m\u1ea1ch. Do s\u1ef1 \u0111\u1ec1 kh\u00e1ng t\u0103ng c\u1ee7a c\u00e1c m\u1ea1ch m\u00e1u \u0111\u1ed9ng m\u1ea1ch t\u1eadn c\u00f9ng, c\u00f3 s\u1ef1 gi\u1ea3m tu\u1ea7n ho\u00e0n c\u1ee7a d\u00e2y th\u1ea7n kinh n\u1ed9i t\u1ea1ng. S\u1ef1 gi\u1ea3m l\u01b0u th\u00f4ng m\u00e1u \u0111\u1ed9ng m\u1ea1ch d\u1eabn \u0111\u1ebfn gi\u1ea3m \u00e1p l\u1ef1c \u1edf tu\u1ea7n ho\u00e0n c\u1eeda. S\u1ef1 co th\u1eaft \u0111\u1ed3ng th\u1eddi c\u00e1c c\u01a1 ru\u1ed9t d\u1eabn \u0111\u1ebfn t\u0103ng nhu \u0111\u1ed9ng ru\u1ed9t. H\u01a1n n\u1eefa, c\u00f3 th\u1ec3 th\u1ea5y l\u00e0 c\u00e1c c\u01a1 c\u1ee7a th\u00e0nh th\u1ef1c qu\u1ea3n co l\u1ea1i v\u00e0 v\u00ec v\u1eady s\u1ef1 gi\u00e3n ch\u1ed7 &#8220;th\u1eaft&#8221; \u0111\u00e3 \u0111\u01b0\u1ee3c t\u1ea1o ra tr\u00ean th\u1ef1c nghi\u1ec7m.<\/p>\n<p><em>Th\u1eadn:<\/em><\/p>\n<p>Terlipressin ch\u1ec9 c\u00f3 3% t\u00e1c d\u1ee5ng ch\u1ed1ng b\u00e0i ni\u1ec7u c\u1ee7a vasopressin t\u1ef1 nhi\u00ean. T\u00ednh ph\u1ea3n \u1ee9ng n\u00e0y kh\u00f4ng c\u00f3 li\u00ean quan v\u1ec1 l\u00e2m s\u00e0ng. Tu\u1ea7n ho\u00e0n th\u1eadn kh\u00f4ng b\u1ecb thay \u0111\u1ed5i \u0111\u00e1ng k\u1ec3 trong t\u00ecnh tr\u1ea1ng th\u1ec3 t\u00edch m\u00e1u b\u00ecnh th\u01b0\u1eddng. Trong t\u00ecnh tr\u1ea1ng gi\u1ea3m l\u01b0u l\u01b0\u1ee3ng m\u00e1u, tu\u1ea7n ho\u00e0n th\u1eadn t\u0103ng l\u00ean.<\/p>\n<p><em>Huy\u1ebft \u00e1p:<\/em><\/p>\n<p>Vi\u1ec7c s\u1eed d\u1ee5ng terlipressin c\u00f3 t\u00e1c \u0111\u1ed9ng v\u1ec1 huy\u1ebft \u0111\u1ed9ng h\u1ecdc ch\u1eadm sau 2-4 gi\u1edd. Huy\u1ebft \u00e1p t\u00e2m thu v\u00e0 t\u00e2m tr\u01b0\u01a1ng t\u0103ng nh\u1eb9. Trong tr\u01b0\u1eddng h\u1ee3p t\u0103ng tr\u01b0\u01a1ng l\u1ef1c th\u1eadn v\u00e0 x\u01a1 c\u1ee9ng m\u1ea1ch m\u00e1u to\u00e0n th\u00e2n, \u0111\u00e3 ghi nh\u1eadn c\u00f3 t\u0103ng huy\u1ebft \u00e1p m\u1ea1nh h\u01a1n.<\/p>\n<p><em>Tim:<\/em><\/p>\n<p>Kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng \u0111\u1ed9c v\u1edbi tim, ngay c\u1ea3 khi d\u00f9ng li\u1ec1u cao nh\u1ea5t \u0111\u00e3 \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh khi d\u00f9ng terlipressin.<\/p>\n<p><em>T\u1eed cung:<\/em><\/p>\n<p>Khi d\u00f9ng terlipressin, tu\u1ea7n ho\u00e0n m\u00e1u c\u1ee7a c\u01a1 t\u1eed cung v\u00e0 n\u1ed9i m\u1ea1c t\u1eed cung b\u1ecb gi\u1ea3m m\u1ea1nh.<\/p>\n<p><em>Da:<\/em><\/p>\n<p>Do t\u00e1c d\u1ee5ng l\u00e0m co m\u1ea1ch, terlipressin d\u1eabn \u0111\u1ebfn thi\u1ebfu tu\u1ea7n ho\u00e0n qua da, v\u00ec v\u1eady m\u1eb7t v\u00e0 c\u01a1 th\u1ec3 b\u1ec7nh nh\u00e2n t\u00e1i xanh.<\/p>\n<p><strong><em>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng: <\/em><\/strong><\/p>\n<p>B\u1ea3n th\u00e2n terlipressin l\u00e0 m\u1ed9t ch\u1ea5t c\u00f3 ho\u1ea1t t\u00ednh, nh\u01b0ng khi v\u00e0o c\u01a1 th\u1ec3, thu\u1ed1c b\u1ecb enzyme chuy\u1ec3n h\u00f3a t\u1ea1o th\u00e0nh lysine vasopressin. Lysine-vasopressin c\u00f3 ho\u1ea1t t\u00ednh sinh h\u1ecdc \u0111\u01b0\u1ee3c ph\u00f3ng th\u00edch k\u00e9o d\u00e0i t\u1eeb terlipressin b\u1edfi enzyme sau khi ti\u00eam t\u0129nh m\u1ea1ch. S\u1ed1 \u00edt glycyl c\u00f2n l\u1ea1i c\u1ee7a triglycylnonapeptide \u0111\u00e3 \u0111\u01b0\u1ee3c chuy\u1ec3n th\u00e0nh d\u1ea1ng t\u1ef1 do m\u1ed9t c\u00e1ch li\u00ean t\u1ee5c.<\/p>\n<p>T\u00e1c d\u1ee5ng v\u1ec1 huy\u1ebft \u0111\u1ed9ng h\u1ecdc v\u00e0 t\u00e1c d\u1ee5ng tr\u00ean c\u00e1c c\u01a1 tr\u01a1n l\u00e0 c\u00e1c y\u1ebfu t\u1ed1 ch\u00ednh trong d\u01b0\u1ee3c l\u00fd h\u1ecdc c\u1ee7a terlipressin. T\u00e1c d\u1ee5ng t\u1eadp trung trong t\u00ecnh tr\u1ea1ng gi\u1ea3m l\u01b0u l\u01b0\u1ee3ng m\u00e1u l\u00e0 m\u1ed9t t\u00e1c d\u1ee5ng ph\u1ee5 c\u00f3 th\u1ec3 g\u1eb7p \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n b\u1ecb gi\u00e3n t\u0129nh m\u1ea1ch th\u1ef1c qu\u1ea3n xu\u1ea5t huy\u1ebft.<\/p>\n<p><strong>[XEM T\u1ea0I \u0110\u00c2Y]<\/strong><\/p>\n<h2><span class=\"ez-toc-section\" id=\"52-duoc-dong-hoc\"><\/span>5.2. D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc:<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc c\u1ee7a thu\u1ed1c theo m\u00f4 h\u00ecnh hai ng\u0103n. Th\u1eddi gian b\u00e1n th\u1ea3i \u0111\u01b0\u1ee3c ghi nh\u1eadn v\u00e0o kho\u1ea3ng 40 ph\u00fat, \u0111\u1ed9 thanh th\u1ea3i chuy\u1ec3n h\u00f3a kho\u1ea3ng 9mL\/kg\/ph\u00fat v\u00e0 th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 kho\u1ea3ng 0,5 L\/kg.<\/p>\n<p>N\u1ed3ng \u0111\u1ed9 mong mu\u1ed1n c\u1ee7a lysine vasopressin trong huy\u1ebft t\u01b0\u01a1ng \u0111\u01b0\u1ee3c ghi nh\u1eadn ban \u0111\u1ea7u sau kho\u1ea3ng 30 ph\u00fat v\u00e0 \u0111\u1ea1t n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh sau 60 \u0111\u1ebfn 120 ph\u00fat sau khi s\u1eed d\u1ee5ng. Do ph\u1ea3n \u1ee9ng ch\u00e9o gi\u1eefa terlipressin v\u00e0 lysine vasopressin x\u1ea3y ra 100%, kh\u00f4ng c\u00f3 ph\u01b0\u01a1ng ph\u00e1p \u0111\u1ecbnh l\u01b0\u1ee3ng b\u1eb1ng mi\u1ec5n d\u1ecbch ph\u00f3ng x\u1ea1 (RIA \u2013 Radioimmunoassay) \u0111\u1eb7c hi\u1ec7u n\u00e0o cho c\u00e1c ch\u1ea5t n\u00e0y.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"53-giai-thich\"><\/span>5.3 Gi\u1ea3i th\u00edch:<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Ch\u01b0a c\u00f3 th\u00f4ng tin. \u0110ang c\u1eadp nh\u1eadt.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"54-thay-the-thuoc\"><\/span>5.4 Thay th\u1ebf thu\u1ed1c :<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Ch\u01b0a c\u00f3 th\u00f4ng tin. \u0110ang c\u1eadp nh\u1eadt.<\/p>\n<p><strong><em>*L\u01b0u \u00fd:<\/em><\/strong><\/p>\n<p><strong><em>C\u00e1c th\u00f4ng tin v\u1ec1 thu\u1ed1c tr\u00ean Pharmog.com ch\u1ec9 mang t\u00ednh ch\u1ea5t tham kh\u1ea3o &#8211; Khi d\u00f9ng thu\u1ed1c c\u1ea7n tuy\u1ec7t \u0111\u1ed1i tu\u00e2n theo theo h\u01b0\u1edbng d\u1eabn c\u1ee7a B\u00e1c s\u0129 <\/em><\/strong><\/p>\n<p><strong><em>Ch\u00fang t\u00f4i kh\u00f4ng ch\u1ecbu tr\u00e1ch nhi\u1ec7m v\u1ec1 b\u1ea5t c\u1ee9 h\u1eadu qu\u1ea3 n\u00e0o x\u1ea3y ra do t\u1ef1 \u00fd d\u00f9ng thu\u1ed1c d\u1ef1a theo c\u00e1c th\u00f4ng tin tr\u00ean Pharmog.com<\/em><\/strong><br \/>\n<script async src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-5528370293090692\" crossorigin=\"anonymous\"><\/script> <ins class=\"adsbygoogle\" style=\"display: block; text-align: center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-5528370293090692\" data-ad-slot=\"8909623906\"><\/ins> <script> (adsbygoogle = window.adsbygoogle || []).push({}); <\/script><\/p>\n<h1><span class=\"ez-toc-section\" id=\"6-phan-thong-tin-kem-theo-cua-thuoc\"><\/span>6. Ph\u1ea7n th\u00f4ng tin k\u00e8m theo c\u1ee7a thu\u1ed1c:<span class=\"ez-toc-section-end\"><\/span><\/h1>\n<h2><span class=\"ez-toc-section\" id=\"61-danh-muc-ta-duoc\"><\/span>6.1. Danh m\u1ee5c t\u00e1 d\u01b0\u1ee3c:<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>&nbsp;<\/p>\n<h2><span class=\"ez-toc-section\" id=\"62-tuong-ky\"><\/span>6.2. T\u01b0\u01a1ng k\u1ef5 :<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Ch\u01b0a c\u00f3 c\u00e1c nghi\u00ean c\u1ee9u v\u1ec1 t\u00ednh t\u01b0\u01a1ng k\u1ef5, thu\u1ed1c n\u00e0y kh\u00f4ng \u0111\u01b0\u1ee3c tr\u1ed9n v\u1edbi c\u00e1c s\u1ea3n ph\u1ea9m thu\u1ed1c kh\u00e1c.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"63-bao-quan\"><\/span>6.3. B\u1ea3o qu\u1ea3n:<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>N\u01a1i kh\u00f4, tr\u00e1nh \u00e1nh s\u00e1ng, nhi\u1ec7t \u0111\u1ed9 d\u01b0\u1edbi 30\u00b0C.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"64-thong-tin-khac\"><\/span>6.4. Th\u00f4ng tin kh\u00e1c :<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Kh\u00f4ng c\u00f3.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"65-tai-lieu-tham-khao\"><\/span>6.5 T\u00e0i li\u1ec7u tham kh\u1ea3o:<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>D\u01b0\u1ee3c Th\u01b0 Qu\u1ed1c Gia Vi\u1ec7t Nam<\/p>\n<p>Ho\u1eb7c HDSD Thu\u1ed1c.<\/p>\n<h1><span class=\"ez-toc-section\" id=\"7-nguoi-dang-tai-tac-gia\"><\/span>7. Ng\u01b0\u1eddi \u0111\u0103ng t\u1ea3i \/T\u00e1c gi\u1ea3:<span class=\"ez-toc-section-end\"><\/span><\/h1>\n<p>B\u00e0i vi\u1ebft \u0111\u01b0\u1ee3c s\u01b0u t\u1ea7m ho\u1eb7c vi\u1ebft b\u1edfi: <a href=\"https:\/\/pharmog.com\/wp\/thong-tin-tac-gia-bac-sy-do-my-linh\/\">B\u00e1c s\u0129 nhi khoa &#8211; \u0110\u1ed7 M\u1ef9 Linh.<\/a><\/p>\n<p>Ki\u1ec3m duy\u1ec7t , hi\u1ec7u \u0111\u00ednh v\u00e0 \u0111\u0103ng t\u1ea3i: <a href=\"https:\/\/pharmog.com\/wp\/thong-tin-ve-pharmog-team\/\">PHARMOG TEAM<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Terlipressin l\u00e0 thu\u1ed1c g\u00ec ? D\u01b0\u1edbi \u0111\u00e2y l\u00e0 n\u1ed9i dung t\u1edd h\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng g\u1ed1c c\u1ee7a Thu\u1ed1c Terlipressin (Th\u00f4ng tin bao g\u1ed3m li\u1ec1u d\u00f9ng, c\u00e1ch d\u00f9ng, ch\u1ec9 \u0111\u1ecbnh, ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh, th\u1eadn tr\u1ecdng, d\u01b0\u1ee3c l\u00fd&#8230;) 1. T\u00ean ho\u1ea1t ch\u1ea5t v\u00e0 bi\u1ec7t d\u01b0\u1ee3c: Ho\u1ea1t ch\u1ea5t : Terlipressin acetate\u00a0 Ph\u00e2n lo\u1ea1i: Thu\u1ed1c co m\u1ea1ch. Thu\u1ed1c [&hellip;]<\/p>\n","protected":false},"author":8612,"featured_media":36192,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[2],"tags":[1431],"class_list":["post-3677","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-thuoc-a-z","tag-terlipressin"],"_links":{"self":[{"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/posts\/3677","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/users\/8612"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/comments?post=3677"}],"version-history":[{"count":6,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/posts\/3677\/revisions"}],"predecessor-version":[{"id":36194,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/posts\/3677\/revisions\/36194"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/media\/36192"}],"wp:attachment":[{"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/media?parent=3677"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/categories?post=3677"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/tags?post=3677"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}