{"id":29407,"date":"2021-02-17T16:44:17","date_gmt":"2021-02-17T09:44:17","guid":{"rendered":"https:\/\/pharmog.com\/wp\/?p=29407"},"modified":"2025-01-08T08:41:03","modified_gmt":"2025-01-08T01:41:03","slug":"repaglinide-pranstad","status":"publish","type":"post","link":"https:\/\/pharmog.com\/wp\/repaglinide-pranstad\/","title":{"rendered":"Repaglinide &#8211; Pranstad"},"content":{"rendered":"<p><em>Thu\u1ed1c Pranstad l\u00e0 thu\u1ed1c g\u00ec ? D\u01b0\u1edbi \u0111\u00e2y l\u00e0 n\u1ed9i dung t\u1edd h\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng g\u1ed1c c\u1ee7a Thu\u1ed1c Pranstad (Th\u00f4ng tin bao g\u1ed3m li\u1ec1u d\u00f9ng, c\u00e1ch d\u00f9ng, ch\u1ec9 \u0111\u1ecbnh, ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh, th\u1eadn tr\u1ecdng, d\u01b0\u1ee3c l\u00fd&#8230;)<\/em><\/p>\n<p><strong>1. T\u00ean ho\u1ea1t ch\u1ea5t v\u00e0 bi\u1ec7t d\u01b0\u1ee3c: <\/strong><\/p>\n<p><strong><em>Ho\u1ea1t ch\u1ea5t :<\/em> <\/strong><a href=\"https:\/\/pharmog.com\/wp\/repaglinide\/\"><strong>Repaglinide<\/strong><\/a><\/p>\n<p><strong><em>Ph\u00e2n lo\u1ea1i: <\/em><\/strong><em>Thu\u00f4\u0301c \u0111i\u00ea\u0300u tri\u0323 ti\u00ea\u0309u \u0111\u01b0\u01a1\u0300ng. Nh\u00f3m Meglitinides<\/em><\/p>\n<p><strong><em>Nh\u00f3m<\/em><\/strong> <strong><em>ph\u00e1p l\u00fd: <\/em><\/strong><em>Thu\u1ed1c k\u00ea \u0111\u01a1n ETC \u2013 (Ethical drugs, prescription drugs, Prescription only medicine)<\/em><\/p>\n<p><strong><em>M\u00e3 ATC<\/em><\/strong> (Anatomical Therapeutic Chemical): A10BX02.<\/p>\n<p><strong><em>Bi\u1ec7t d\u01b0\u1ee3c g\u1ed1c: <\/em><\/strong><\/p>\n<p><strong><em>Bi\u1ec7t d\u01b0\u1ee3c:<\/em><\/strong> Pranstad<\/p>\n<p><strong><em>H\u00e3ng s\u1ea3n xu\u1ea5t <\/em><\/strong>: C\u00f4ng ty TNHH Li\u00ean Doanh Stellapharm<\/p>\n<p><script src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-5528370293090692\" async=\"\" crossorigin=\"anonymous\"><\/script><ins class=\"adsbygoogle\" style=\"display: block; text-align: center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-5528370293090692\" data-ad-slot=\"8909623906\"><\/ins><script> (adsbygoogle = window.adsbygoogle || []).push({}); <\/script><\/p>\n<p><strong>2. D\u1ea1ng b\u00e0o ch\u1ebf &#8211; H\u00e0m l\u01b0\u1ee3ng: <\/strong><\/p>\n<p><strong><em>D\u1ea1ng thu\u1ed1c v\u00e0 h\u00e0m l\u01b0\u1ee3ng<\/em><\/strong><\/p>\n<p>Vi\u00ean n\u00e9n 1 mg: h\u1ed9p 3 v\u1ec9 x 10 vi\u00ean, h\u1ed9p 6 v\u1ec9 x 10 vi\u00ean..<\/p>\n<p><strong><em>Thu\u1ed1c tham kh\u1ea3o:<\/em><\/strong><\/p>\n<table>\n<tbody>\n<tr>\n<td colspan=\"2\"><strong><em>PRANSTAD 1 (STELLA)<\/em><\/strong><\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\"><em>M\u1ed7i vi\u00ean n\u00e9n bao phim c\u00f3 ch\u1ee9a:<\/em><\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td>Repaglinide<\/td>\n<td>&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.<\/td>\n<td>1 mg<\/td>\n<\/tr>\n<tr>\n<td>T\u00e1 d\u01b0\u1ee3c<\/td>\n<td>&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.<\/td>\n<td>v\u1eeba \u0111\u1ee7 (Xem m\u1ee5c 6.1)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><img loading=\"lazy\" decoding=\"async\" width=\"526\" height=\"284\" class=\"wp-image-29408\" src=\"https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2021\/02\/word-image-199.png\" srcset=\"https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2021\/02\/word-image-199.png 526w, https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2021\/02\/word-image-199-300x162.png 300w\" sizes=\"auto, (max-width: 526px) 100vw, 526px\" \/><\/p>\n<table>\n<tbody>\n<tr>\n<td colspan=\"2\"><strong><em>PRANSTAD 1 (STADA)<\/em><\/strong><\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\"><em>M\u1ed7i vi\u00ean n\u00e9n bao phim c\u00f3 ch\u1ee9a:<\/em><\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td>Repaglinide<\/td>\n<td>&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.<\/td>\n<td>1 mg<\/td>\n<\/tr>\n<tr>\n<td>T\u00e1 d\u01b0\u1ee3c<\/td>\n<td>&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.<\/td>\n<td>v\u1eeba \u0111\u1ee7 (Xem m\u1ee5c 6.1)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><img loading=\"lazy\" decoding=\"async\" width=\"409\" height=\"320\" class=\"wp-image-29409\" src=\"https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2021\/02\/word-image-200.png\" srcset=\"https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2021\/02\/word-image-200.png 409w, https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2021\/02\/word-image-200-300x235.png 300w\" sizes=\"auto, (max-width: 409px) 100vw, 409px\" \/><\/p>\n<p><strong>3. Video by Pharmog:<\/strong><\/p>\n<p><strong>[VIDEO D\u01af\u1ee2C L\u00dd]<\/strong><\/p>\n<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<\/p>\n<p>\u25ba K\u1ecbch B\u1ea3n: PharmogTeam<\/p>\n<p>\u25ba Youtube: https:\/\/www.youtube.com\/c\/pharmog<\/p>\n<p>\u25ba Facebook: https:\/\/www.facebook.com\/pharmog\/<\/p>\n<p>\u25ba Group : H\u1ed9i nh\u1eefng ng\u01b0\u1eddi m\u00ea d\u01b0\u1ee3c l\u00fd<\/p>\n<p>\u25ba Instagram : https:\/\/www.instagram.com\/pharmogvn\/<\/p>\n<p>\u25ba Website: pharmog.com<\/p>\n<p><strong>4. \u1ee8ng d\u1ee5ng l\u00e2m s\u00e0ng: <\/strong><\/p>\n<p><strong>4.1. Ch\u1ec9 \u0111\u1ecbnh:<\/strong><\/p>\n<p>Pranstad 1 \u0111\u01b0\u1ee3c d\u00f9ng \u0111\u01a1n tr\u1ecb h\u1ed7 tr\u1ee3 cho ch\u1ebf \u0111\u1ed9 \u0103n ki\u00eang v\u00e0 t\u1eadp th\u1ec3 d\u1ee5c trong \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng typ 2 (kh\u00f4ng ph\u1ee5 thu\u1ed9c insulin) \u1edf b\u1ec7nh nh\u00e2n c\u00f3 glucose huy\u1ebft cao kh\u00f4ng ki\u1ec3m so\u00e1t \u0111\u01b0\u1ee3c b\u1eb1ng ch\u1ebf \u0111\u1ed9 \u0103n ki\u00eang v\u00e0 t\u1eadp th\u1ec3 d\u1ee5c \u0111\u01a1n thu\u1ea7n.<\/p>\n<p>Pranstad 1 c\u00f3 th\u1ec3 ph\u1ed1i h\u1ee3p v\u1edbi metformin \u1edf b\u1ec7nh nh\u00e2n c\u00f3 glucose huy\u1ebft cao kh\u00f4ng \u0111\u01b0\u1ee3c ki\u1ec3m so\u00e1t th\u1ecfa \u0111\u00e1ng b\u1eb1ng ch\u1ebf \u0111\u1ed9 \u0103n ki\u00eang, t\u1eadp th\u1ec3 d\u1ee5c v\u00e0 \u0111\u01a1n tr\u1ecb v\u1edbi metformin, sulfonylur\u00ea, repaglinide hay thiazolidinedion.<\/p>\n<p><strong>4.2. Li\u1ec1u d\u00f9ng &#8211; C\u00e1ch d\u00f9ng:<\/strong><\/p>\n<p><strong><em>C\u00e1ch d\u00f9ng<\/em><\/strong> :<\/p>\n<p>U\u1ed1ng tr\u01b0\u1edbc m\u1ed7i b\u1eefa \u0103n trong v\u00f2ng 15 ph\u00fat, tuy nhi\u00ean c\u00f3 th\u1ec3 dao \u0111\u1ed9ng t\u1eeb tr\u01b0\u1edbc b\u1eefa \u0103n 30 ph\u00fat \u0111\u1ebfn ngay tr\u01b0\u1edbc b\u1eefa \u0103n.<\/p>\n<p><strong><em>Li\u1ec1u d\u00f9ng:<\/em><\/strong><\/p>\n<p><em>Li\u1ec1u kh\u1edfi \u0111\u1ea7u<\/em><\/p>\n<p>\u0110\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n ch\u01b0a t\u1eebng \u0111i\u1ec1u tr\u1ecb tr\u01b0\u1edbc \u0111\u00e2y ho\u1eb7c c\u00f3 HbA1C &lt; 8%: N\u00ean kh\u1edfi \u0111\u1ea7u v\u1edbi li\u1ec1u 0,5 mg tr\u01b0\u1edbc b\u1eefa \u0103n.<\/p>\n<p>\u0110\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n \u0111\u00e3 t\u1eebng \u0111i\u1ec1u tr\u1ecb v\u1edbi c\u00e1c thu\u1ed1c h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft v\u00e0 c\u00f3 HbA1C \u2265 8%: Li\u1ec1u kh\u1edfi \u0111\u1ea7u l\u00e0 1-2 mg tr\u01b0\u1edbc b\u1eefa \u0103n.<\/p>\n<p><em>\u0110i\u1ec1u ch\u1ec9nh li\u1ec1u<\/em><\/p>\n<p>\u0110i\u1ec1u ch\u1ec9nh li\u1ec1u n\u00ean x\u00e1c \u0111\u1ecbnh b\u1eb1ng \u0111\u00e1p \u1ee9ng glucose huy\u1ebft, th\u01b0\u1eddng l\u00e0 glucose huy\u1ebft khi \u0111\u00f3i.<\/p>\n<p>Li\u1ec1u tr\u01b0\u1edbc b\u1eefa \u0103n n\u00ean \u0111\u01b0\u1ee3c t\u0103ng g\u1ea5p \u0111\u00f4i \u0111\u1ebfn 4 mg cho \u0111\u1ebfn khi m\u1ee9c glucose huy\u1ebft \u0111\u1ea1t y\u00eau c\u1ea7u. \u0110\u00e1nh gi\u00e1 \u0111\u00e1p \u1ee9ng sau m\u1ed7i l\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u \u00edt nh\u1ea5t m\u1ed9t tu\u1ea7n.<\/p>\n<p>Thang li\u1ec1u \u0111\u1ec1 ngh\u1ecb t\u1eeb 0,5 mg \u0111\u1ebfn 4 mg. Pranstad 1 c\u00f3 th\u1ec3 d\u00f9ng tr\u01b0\u1edbc b\u1eefa \u0103n 2, 3, ho\u1eb7c 4 l\u1ea7n\/ng\u00e0y t\u00f9y thu\u1ed9c v\u00e0o ki\u1ec3u b\u1eefa \u0103n c\u1ee7a b\u1ec7nh nh\u00e2n. Li\u1ec1u t\u1ed1i \u0111a trong ng\u00e0y l\u00e0 16 mg.<\/p>\n<p><em>B\u1ec7nh nh\u00e2n \u0111ang d\u00f9ng thu\u1ed1c \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng kh\u00e1c<\/em><\/p>\n<p>B\u1ec7nh nh\u00e2n c\u00f3 th\u1ec3 chuy\u1ec3n tr\u1ef1c ti\u1ebfp t\u1eeb c\u00e1c thu\u1ed1c \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng d\u1ea1ng u\u1ed1ng kh\u00e1c sang repaglinide. Li\u1ec1u t\u1ed1i \u0111a b\u1eaft \u0111\u1ea7u chuy\u1ec3n sang d\u00f9ng repaglinide l\u00e0 1 mg tr\u01b0\u1edbc b\u1eefa \u0103n ch\u00ednh.<\/p>\n<p><em>Ph\u1ed1i h\u1ee3p v\u1edbi metformin<\/em><\/p>\n<p>C\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u c\u1ee7a m\u1ed7i thu\u1ed1c \u0111\u1ec3 ki\u1ec3m so\u00e1t \u0111\u01b0\u1ee3c glucose huy\u1ebft, m\u1ed7i thu\u1ed1c n\u00ean d\u00f9ng li\u1ec1u th\u1ea5p nh\u1ea5t c\u00f3 hi\u1ec7u qu\u1ea3.<\/p>\n<p><em>Nh\u00f3m b\u1ec7nh nh\u00e2n \u0111\u1eb7c bi\u1ec7t<\/em><\/p>\n<p>B\u1ec7nh nh\u00e2n b\u1ecb suy th\u1eadn n\u1eb7ng (\u0111\u1ed9 thanh th\u1ea3i creatinin t\u1eeb 20-40mL\/ph\u00fat) n\u00ean b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb b\u1eb1ng repaglinide v\u1edbi li\u1ec1u 0,5 mg, sau \u0111\u00f3 c\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u c\u1ea9n th\u1eadn.<\/p>\n<p>Ch\u01b0a c\u00f3 nghi\u00ean c\u1ee9u l\u00e2m s\u00e0ng \u1edf tr\u1ebb em v\u00e0 thanh thi\u1ebfu ni\u00ean &lt; 18 tu\u1ed5i ho\u1eb7c b\u1ec7nh nh\u00e2n &gt;75 tu\u1ed5i. V\u00ec v\u1eady kh\u00f4ng khuy\u00ean d\u00f9ng cho nh\u00f3m b\u1ec7nh nh\u00e2n n\u00e0y.<\/p>\n<p><strong>4.3. Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh:<\/strong><\/p>\n<p>B\u1ec7nh nh\u00e2n qu\u00e1 m\u1eabn v\u1edbi thu\u1ed1c.<\/p>\n<p>B\u1ec7nh nh\u00e2n \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng typ 1.<\/p>\n<p>B\u1ec7nh nh\u00e2n \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng b\u1ecb bi\u1ebfn ch\u1ee9ng nhi\u1ec5m toan chuy\u1ec3n h\u00f3a c\u1ea5p t\u00ednh ho\u1eb7c m\u1ea1n t\u00ednh, k\u1ec3 c\u1ea3 nhi\u1ec5m acid-ceton do \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng, c\u00f3 ho\u1eb7c kh\u00f4ng c\u00f3 h\u00f4n m\u00ea; tr\u01b0\u1eddng h\u1ee3p n\u00e0y ph\u1ea3i d\u00f9ng insulin.<\/p>\n<p><strong>4.4 Th\u1eadn tr\u1ecdng:<\/strong><\/p>\n<p>Repaglinide kh\u00f4ng \u0111\u01b0\u1ee3c d\u00f9ng chung v\u1edbi NPH-insulin.<\/p>\n<p>T\u1ea5t c\u1ea3 c\u00e1c thu\u1ed1c h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft k\u1ec3 c\u1ea3 repaglinide \u0111\u1ec1u c\u00f3 kh\u1ea3 n\u0103ng g\u00e2y h\u1ea1 glucose huy\u1ebft.<\/p>\n<p>Suy gan c\u00f3 th\u1ec3 g\u00e2y t\u0103ng n\u1ed3ng \u0111\u1ed9 repaglinide trong m\u00e1u cao v\u00e0 c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m kh\u1ea3 n\u0103ng t\u00e2n t\u1ea1o glucose, c\u1ea3 hai \u0111i\u1ec1u n\u00e0y l\u00e0m t\u0103ng nguy c\u01a1 h\u1ea1 glucose huy\u1ebft nghi\u00eam tr\u1ecdng.<\/p>\n<p>Ng\u01b0\u1eddi cao tu\u1ed5i, b\u1ec7nh nh\u00e2n suy nh\u01b0\u1ee3c ho\u1eb7c suy dinh d\u01b0\u1ee1ng v\u00e0 suy tuy\u1ebfn th\u01b0\u1ee3ng th\u1eadn, suy gan, suy tuy\u1ebfn y\u00ean, ho\u1eb7c suy th\u1eadn n\u1eb7ng \u0111\u1eb7c bi\u1ec7t nh\u1ea1y c\u1ea3m v\u1edbi t\u00e1c d\u1ee5ng h\u1ea1 glucose huy\u1ebft.<\/p>\n<p>Tri\u1ec7u ch\u1ee9ng h\u1ea1 glucose huy\u1ebft kh\u00f3 nh\u1eadn th\u1ea5y \u1edf ng\u01b0\u1eddi cao tu\u1ed5i, ng\u01b0\u1eddi d\u00f9ng thu\u1ed1c ch\u1eb9n beta-adrenergic. H\u1ea1 glucose huy\u1ebft th\u01b0\u1eddng x\u1ea3y ra khi l\u01b0\u1ee3ng calori \u0111\u01b0a v\u00e0o c\u01a1 th\u1ec3 kh\u00f4ng \u0111\u1ee7, sau khi ho\u1ea1t \u0111\u1ed9ng th\u1ec3 l\u1ef1c n\u1eb7ng ho\u1eb7c k\u00e9o d\u00e0i, u\u1ed1ng r\u01b0\u1ee3u ho\u1eb7c d\u00f9ng \u0111\u1ed3ng th\u1eddi nhi\u1ec1u lo\u1ea1i thu\u1ed1c h\u1ea1 glucose huy\u1ebft.<\/p>\n<p>Khi b\u1ec7nh nh\u00e2n \u0111\u00e3 \u1ed5n \u0111\u1ecbnh v\u1edbi m\u1ed9t ph\u00e1c \u0111\u1ed3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng khi g\u1eb7p stress nh\u01b0 s\u1ed1t, ch\u1ea5n th\u01b0\u01a1ng, nhi\u1ec5m tr\u00f9ng ho\u1eb7c ph\u1eabu thu\u1eadt, s\u1ef1 m\u1ea5t ki\u1ec3m so\u00e1t glucose huy\u1ebft c\u00f3 th\u1ec3 x\u1ea3y ra. L\u00fac n\u00e0y, n\u00ean ng\u01b0ng d\u00f9ng repaglinide v\u00e0 thay b\u1eb1ng insulin.<\/p>\n<p><script src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-5528370293090692\" async=\"\" crossorigin=\"anonymous\"><\/script><ins class=\"adsbygoogle\" style=\"display: block; text-align: center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-5528370293090692\" data-ad-slot=\"8909623906\"><\/ins><script> (adsbygoogle = window.adsbygoogle || []).push({}); <\/script><\/p>\n<p><strong>T\u00e1c \u0111\u1ed9ng c\u1ee7a thu\u1ed1c tr\u00ean ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/strong><\/p>\n<p>B\u1ec7nh nh\u00e2n c\u1ea7n th\u1eadn tr\u1ecdng tr\u00e1nh \u0111\u1ec3 h\u1ea1 glucose huy\u1ebft trong khi \u0111ang l\u00e1i xe. \u0110i\u1ec1u n\u00e0y \u0111\u1eb7c bi\u1ec7t quan tr\u1ecdng \u1edf nh\u1eefng ng\u01b0\u1eddi kh\u00f3 nh\u1eadn bi\u1ebft nh\u1eefng d\u1ea5u hi\u1ec7u c\u1ee7a h\u1ea1 glucose huy\u1ebft hay th\u01b0\u1eddng xuy\u00ean b\u1ecb h\u1ea1 glucose huy\u1ebft. Vi\u1ec7c l\u00e1i xe n\u00ean \u0111\u01b0\u1ee3c c\u00e2n nh\u1eafc trong nh\u1eefng tr\u01b0\u1eddng h\u1ee3p n\u00e0y.<\/p>\n<p><strong>4.5 S\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa:<\/strong><\/p>\n<p><em>X\u1ebfp h\u1ea1ng c\u1ea3nh b\u00e1o<\/em><\/p>\n<p>AU TGA pregnancy category: C<\/p>\n<p>US FDA pregnancy category: C<\/p>\n<p><em>Th\u1eddi k\u1ef3 mang thai:<\/em><\/p>\n<p>Ch\u01b0a c\u00f3 nghi\u00ean c\u1ee9u v\u1ec1 \u0111\u1ed9 an to\u00e0n c\u1ee7a repaglinide tr\u00ean ph\u1ee5 n\u1eef mang thai, n\u00ean ch\u1ec9 d\u00f9ng repaglinide cho ph\u1ee5 n\u1eef mang thai khi th\u1eadt s\u1ef1 c\u1ea7n thi\u1ebft.<\/p>\n<p>N\u1ed3ng \u0111\u1ed9 glucose huy\u1ebft b\u1ea5t th\u01b0\u1eddng trong th\u1eddi k\u1ef3 mang thai c\u00f3 th\u1ec3 li\u00ean quan \u0111\u1ebfn s\u1ef1 t\u0103ng t\u1ec9 l\u1ec7 d\u1ecb t\u1eadt b\u1ea9m sinh, insulin \u0111\u01b0\u1ee3c khuy\u00ean d\u00f9ng thay th\u1ebf cho repaglinide trong th\u1eddi k\u1ef3 mang thai \u0111\u1ec3 duy tr\u00ec ki\u1ec3m so\u00e1t n\u1ed3ng \u0111\u1ed9 glucose huy\u1ebft t\u1ed1i \u01b0u.<\/p>\n<p><em>Th\u1eddi k\u1ef3 cho con b\u00fa<\/em><\/p>\n<p>Do kh\u1ea3 n\u0103ng repaglinide g\u00e2y h\u1ea1 glucose huy\u1ebft v\u00e0 bi\u1ebfn \u0111\u1ed5i x\u01b0\u01a1ng c\u00f3 th\u1ec3 x\u1ea3y ra \u1edf tr\u1ebb \u0111ang b\u00fa s\u1eefa m\u1eb9, n\u00ean ng\u01b0ng d\u00f9ng thu\u1ed1c ho\u1eb7c ng\u01b0ng cho con b\u00fa, c\u00e2n nh\u1eafc t\u1ea7m quan tr\u1ecdng c\u1ee7a thu\u1ed1c \u0111\u1ed1i v\u1edbi ng\u01b0\u1eddi m\u1eb9. N\u1ebfu ng\u01b0ng d\u00f9ng repaglinide v\u00e0 ch\u1ebf \u0111\u1ed9 \u0103n ki\u00eang kh\u00f4ng \u0111\u1ee7 \u0111\u1ec3 ki\u1ec3m so\u00e1t glucose huy\u1ebft th\u00ec d\u00f9ng insulin thay th\u1ebf.<\/p>\n<p><strong>4.6 T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n (ADR):<\/strong><\/p>\n<p><em>Th\u01b0\u1eddng g\u1eb7p (1\/100 \u2264 ADR &lt; 1\/10)<\/em><\/p>\n<p>Chuy\u1ec3n h\u00f3a: H\u1ea1 glucose huy\u1ebft.<\/p>\n<p>H\u00f4 h\u1ea5p: Nhi\u1ec5m tr\u00f9ng \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p tr\u00ean, vi\u00eam xoang, vi\u00eam m\u0169i, vi\u00eam ph\u1ebf qu\u1ea3n.<\/p>\n<p>Ti\u00eau h\u00f3a: Bu\u1ed3n n\u00f4n, ti\u00eau ch\u1ea3y.<\/p>\n<p>C\u01a1 x\u01b0\u01a1ng: \u0110au kh\u1edbp, \u0111au l\u01b0ng.<\/p>\n<p>Th\u1ea7n kinh: \u0110au \u0111\u1ea7u.<\/p>\n<p><em>\u00cdt g\u1eb7p (1\/1.000 \u2264 ADR &lt; 1\/100)<\/em><\/p>\n<p>Ti\u00eau h\u00f3a: T\u00e1o b\u00f3n, n\u00f4n, kh\u00f3 ti\u00eau.<\/p>\n<p>Kh\u00e1c: D\u1ecb c\u1ea3m, \u0111au ng\u1ef1c, nhi\u1ec5m tr\u00f9ng \u0111\u01b0\u1eddng ti\u1ebft ni\u1ec7u, d\u1ecb \u1ee9ng.<\/p>\n<p><em>Th\u00f4ng b\u00e1o cho B\u00e1c s\u0129 nh\u1eefng t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n g\u1eb7p ph\u1ea3i khi s\u1eed d\u1ee5ng thu\u1ed1c.<\/em><\/p>\n<p><strong>4.7 H\u01b0\u1edbng d\u1eabn c\u00e1ch x\u1eed tr\u00ed ADR:<\/strong><\/p>\n<p>C\u00e1c tai bi\u1ebfn tr\u00ean (tr\u1eeb t\u1ee5t \u0111\u01b0\u1eddng huy\u1ebft) th\u01b0\u1eddng x\u1ea3y ra trong giai \u0111o\u1ea1n \u0111\u1ea7u khi th\u0103m d\u00f2 li\u1ec1u v\u00e0 th\u01b0\u1eddng gi\u1ea3m, r\u1ed3i m\u1ea5t \u0111i trong qu\u00e1 tr\u00ecnh \u0111i\u1ec1u tr\u1ecb. Tr\u01b0\u1eddng h\u1ee3p n\u1eb7ng, ph\u1ea3i ng\u1eebng thu\u1ed1c.<\/p>\n<p><strong>4.8 T\u01b0\u01a1ng t\u00e1c v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1c:<\/strong><\/p>\n<p><em>Nh\u1eefng thu\u1ed1c \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn enzym gan<\/em><\/p>\n<p>Ph\u1ed1i h\u1ee3p repaglinide v\u1edbi c\u00e1c thu\u1ed1c c\u1ea3m \u1ee9ng isoenzym CYP3A4 hay CYP2C8 nh\u01b0 troglitazon, rifampin, barbiturat, carmabazepin v\u1ec1 l\u00fd thuy\u1ebft c\u00f3 th\u1ec3 l\u00e0m t\u0103ng chuy\u1ec3n h\u00f3a repaglinide.<\/p>\n<p>Ph\u1ed1i h\u1ee3p repaglinide v\u1edbi c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf isoenzym CYP2C8, nh\u01b0 gemfibrozil, trimethoprim ho\u1eb7c montelukast, c\u00f3 th\u1ec3 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 repaglinide trong huy\u1ebft t\u01b0\u01a1ng.<\/p>\n<p><em>Nh\u1eefng thu\u1ed1c g\u1eafn k\u1ebft protein<\/em><\/p>\n<p>Salicylat ho\u1eb7c c\u00e1c thu\u1ed1c kh\u00e1ng vi\u00eam kh\u00f4ng steroid kh\u00e1c, sulfonamid, probenecid, cloramphenicol, thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng m\u00e1u d\u1ea1ng u\u1ed1ng (nh\u01b0 warfarin), thu\u1ed1c \u1ee9c ch\u1ebf monoamin oxidase, thu\u1ed1c \u1ee9c ch\u1ebf HMG-CoA reductase, thu\u1ed1c ch\u1eb9n beta-adrenergic. Khi b\u1eaft \u0111\u1ea7u hay ng\u1eebng s\u1eed d\u1ee5ng nh\u1eefng thu\u1ed1c n\u00e0y trong khi b\u1ec7nh nh\u00e2n \u0111ang d\u00f9ng repaglinide, b\u1ec7nh nh\u00e2n c\u1ea7n theo d\u00f5i nh\u1eefng bi\u1ec3u hi\u1ec7n h\u1ea1 glucose huy\u1ebft hay m\u1ea5t ki\u1ec3m so\u00e1t glucose huy\u1ebft.<\/p>\n<p><em>Thu\u1ed1c kh\u00e1c<\/em><\/p>\n<p>Nh\u1eefng thu\u1ed1c g\u00e2y t\u0103ng glucose huy\u1ebft v\u00e0 c\u00f3 th\u1ec3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn vi\u1ec7c ki\u1ec3m so\u00e1t glucose huy\u1ebft \u1edf b\u1ec7nh nh\u00e2n \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng bao g\u1ed3m: Corticosteroid, niacin, thu\u1ed1c l\u1ee3i ti\u1ec3u thiazid v\u00e0 c\u00e1c thu\u1ed1c l\u1ee3i ti\u1ec3u kh\u00e1c, thu\u1ed1c ng\u1eeba thai d\u1ea1ng u\u1ed1ng, thu\u1ed1c c\u01b0\u1eddng giao c\u1ea3m, thu\u1ed1c c\u01b0\u1eddng gi\u00e1p, estrogen, phenytoin, phenothiazin, thu\u1ed1c ch\u1eb9n k\u00eanh calci v\u00e0 isoniazid.<\/p>\n<p><script src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-5528370293090692\" async=\"\" crossorigin=\"anonymous\"><\/script><ins class=\"adsbygoogle\" style=\"display: block; text-align: center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-5528370293090692\" data-ad-slot=\"8909623906\"><\/ins><script> (adsbygoogle = window.adsbygoogle || []).push({}); <\/script><\/p>\n<p><strong>4.9 Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed:<\/strong><\/p>\n<p>Bi\u1ec3u hi\u1ec7n qu\u00e1 li\u1ec1u c\u1ea5p t\u00ednh repaglinide ch\u1ee7 y\u1ebfu l\u00e0 h\u1ea1 glucose huy\u1ebft.<\/p>\n<p>C\u00e1c tri\u1ec7u ch\u1ee9ng h\u1ea1 glucose huy\u1ebft m\u00e0 kh\u00f4ng m\u1ea5t \u00fd th\u1ee9c hay \u0111\u1ed9c th\u1ea7n kinh: U\u1ed1ng ngay glucose v\u00e0 \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u d\u00f9ng thu\u1ed1c v\u00e0\/ho\u1eb7c ch\u1ebf \u0111\u1ed9 \u0103n. B\u1ec7nh nh\u00e2n n\u00ean \u0111\u01b0\u1ee3c theo d\u00f5i ch\u1eb7t ch\u1ebd \u00edt nh\u1ea5t 24 \u0111\u1ebfn 48 gi\u1edd, v\u00ec h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft c\u00f3 th\u1ec3 t\u00e1i ph\u00e1t sau khi \u0111\u00e3 h\u1ed3i ph\u1ee5c l\u00e2m s\u00e0ng r\u00f5 r\u00e0ng. Ch\u01b0a c\u00f3 b\u1eb1ng ch\u1ee9ng r\u1eb1ng repaglinide \u0111\u01b0\u1ee3c lo\u1ea1i b\u1ecf b\u1eb1ng ph\u01b0\u01a1ng ph\u00e1p th\u1ea9m t\u00e1ch m\u00e1u.<\/p>\n<p>H\u1ea1 glucose huy\u1ebft tr\u1ea7m tr\u1ecdng k\u00e8m h\u00f4n m\u00ea, co gi\u1eadt ho\u1eb7c suy nh\u01b0\u1ee3c th\u1ea7n kinh \u00edt khi x\u1ea3y ra, c\u1ea7n ph\u1ea3i c\u1ea5p c\u1ee9u v\u00e0 \u0111\u01b0a ngay v\u00e0o b\u1ec7nh vi\u1ec7n. N\u1ebfu b\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n hay nghi ng\u1edd b\u1ecb h\u00f4n m\u00ea do h\u1ea1 glucose huy\u1ebft, ti\u00eam t\u0129nh m\u1ea1ch nhanh dung d\u1ecbch glucose (n\u1ed3ng \u0111\u1ed9 50%). Sau \u0111\u00f3 ti\u1ebfp t\u1ee5c truy\u1ec1n dung d\u1ecbch glucose lo\u00e3ng h\u01a1n (n\u1ed3ng \u0111\u1ed9 10%) v\u1edbi t\u1ed1c \u0111\u1ed9 c\u00f3 th\u1ec3 duy tr\u00ec n\u1ed3ng \u0111\u1ed9 glucose huy\u1ebft \u1edf m\u1ee9c tr\u00ean 100mg\/dL.<\/p>\n<p><strong>5. C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c :<\/strong><\/p>\n<p><strong>5.1. D\u01b0\u1ee3c l\u1ef1c h\u1ecdc:<\/strong><\/p>\n<p>Nh\u00f3m d\u01b0\u1ee3c l\u00fd: Thu\u1ed1c ch\u1ed1ng \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng; c\u00e1c thu\u1ed1c gi\u1ea3m glucose huy\u1ebft kh\u00e1c, tr\u1eeb insulin.<\/p>\n<p>M\u00e3 ATC: A10BX02<\/p>\n<p>Repaglinide l\u00e0m gi\u1ea3m m\u1ee9c glucose huy\u1ebft b\u1eb1ng c\u00e1ch k\u00edch th\u00edch ti\u1ebft insulin t\u1eeb tuy\u1ebfn t\u1ee5y. T\u00e1c d\u1ee5ng n\u00e0y ph\u1ee5 thu\u1ed9c v\u00e0o ch\u1ee9c n\u0103ng c\u1ee7a t\u1ebf b\u00e0o beta c\u1ee7a \u0111\u1ea3o t\u1ee5y.<\/p>\n<p>S\u1ef1 ph\u00f3ng th\u00edch insulin ph\u1ee5 thu\u1ed9c v\u00e0o glucose v\u00e0 gi\u1ea3m khi n\u1ed3ng \u0111\u1ed9 glucose \u1edf m\u1ee9c th\u1ea5p.<\/p>\n<p>Repaglinide \u0111\u00f3ng c\u00e1c k\u00eanh kali ph\u1ee5 thu\u1ed9c ATP \u1edf m\u00e0ng t\u1ebf b\u00e0o beta b\u1eb1ng c\u00e1ch g\u1eafn k\u1ebft t\u1ea1i c\u00e1c v\u1ecb tr\u00ed chuy\u00ean bi\u1ec7t. S\u1ef1 \u0111\u00f3ng k\u00eanh kali g\u00e2y kh\u1eed c\u1ef1c t\u1ebf b\u00e0o beta, d\u1eabn \u0111\u1ebfn m\u1edf c\u00e1c k\u00eanh calci. K\u1ebft qu\u1ea3 c\u1ee7a s\u1ef1 t\u0103ng d\u00f2ng canxi g\u00e2y ti\u1ebft insulin. C\u01a1 ch\u1ebf k\u00eanh ion c\u00f3 t\u00ednh ch\u1ecdn l\u1ecdc m\u00f4 cao v\u1edbi \u00e1i l\u1ef1c th\u1ea5p \u1edf c\u01a1 tim v\u00e0 c\u01a1 x\u01b0\u01a1ng.<\/p>\n<p><strong><em>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng: <\/em><\/strong><\/p>\n<p>Repaglinid l\u00e0m gi\u1ea3m m\u1ee9c glucose huy\u1ebft c\u1ea5p th\u1eddi b\u1eb1ng c\u00e1ch k\u00edch th\u00edch s\u1ef1 ph\u00f3ng th\u00edch insulin t\u1eeb t\u1ee5y, hi\u1ec7u qu\u1ea3 n\u00e0y ph\u1ee5 thu\u1ed9c v\u00e0o ho\u1ea1t \u0111\u1ed9ng c\u1ee7a t\u1ebf b\u00e0o \u03b2 trong ti\u1ec3u \u0111\u1ea3o t\u1ee5y.<\/p>\n<p>Repaglinid l\u00e0m \u0111\u00f3ng c\u00e1c k\u00eanh kali ph\u1ee5 thu\u1ed9c ATP tr\u00ean m\u00e0ng t\u1ebf b\u00e0o \u03b2 th\u00f4ng qua 1 lo\u1ea1i protein \u0111\u00edch kh\u00e1c v\u1edbi c\u00e1c t\u00e1c nh\u00e2n k\u00edch th\u00edch ti\u1ebft insulin kh\u00e1c.<\/p>\n<p>T\u00e1c \u0111\u1ed9ng n\u00e0y l\u00e0m kh\u1eed c\u1ef1c t\u1ebf b\u00e0o \u03b2 v\u00e0 d\u1eabn \u0111\u1ebfn vi\u1ec7c m\u1edf k\u00eanh calcium, k\u1ebft qu\u1ea3 l\u00e0m t\u0103ng d\u00f2ng calcium v\u00e0o t\u1ebf b\u00e0o. \u0110i\u1ec1u n\u00e0y g\u00e2y ra s\u1ef1 ti\u1ebft insulin t\u1eeb t\u1ebf b\u00e0o \u03b2.<\/p>\n<p><strong>[XEM T\u1ea0I \u0110\u00c2Y]<\/strong><\/p>\n<p><strong>5.2. D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc:<\/strong><\/p>\n<p>Repaglinide \u0111\u01b0\u1ee3c h\u1ea5p thu nhanh qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a, n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng \u0111\u1ea1t \u0111\u01b0\u1ee3c trong v\u00f2ng 1 gi\u1edd. Sinh kh\u1ea3 d\u1ee5ng trung b\u00ecnh kho\u1ea3ng 60%.<\/p>\n<p>Repaglinide li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng cao v\u00e0 th\u1eddi gian b\u00e1n th\u1ea3i trong huy\u1ebft t\u01b0\u01a1ng kho\u1ea3ng 1 gi\u1edd. Repaglinide chuy\u1ec3n h\u00f3a h\u1ea7u nh\u01b0 ho\u00e0n to\u00e0n \u1edf gan th\u00f4ng qua h\u1ec7 th\u1ed1ng cytochrom P450 isoenzym CYP2C8 v\u00e0 CYP3A4. C\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a kh\u00f4ng c\u00f3 ho\u1ea1t t\u00ednh \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb qua m\u1eadt. \u1ede b\u1ec7nh nh\u00e2n b\u1ecb suy th\u1eadn (\u0111\u1ed9 thanh th\u1ea3i creatinin \u00edt h\u01a1n 40ml\/ph\u00fat) ho\u1eb7c m\u1eafc b\u1ec7nh gan m\u00e3n t\u00ednh, n\u1ed3ng \u0111\u1ed9 repaglinide trong huy\u1ebft t\u01b0\u01a1ng cao h\u01a1n v\u00e0 th\u1eddi gian b\u00e1n th\u1ea3i d\u00e0i h\u01a1n.<\/p>\n<p><strong>5.3 Gi\u1ea3i th\u00edch: <\/strong><\/p>\n<p>Ch\u01b0a c\u00f3 th\u00f4ng tin. \u0110ang c\u1eadp nh\u1eadt.<\/p>\n<p><strong>5.4 Thay th\u1ebf thu\u1ed1c : <\/strong><\/p>\n<p>Ch\u01b0a c\u00f3 th\u00f4ng tin. \u0110ang c\u1eadp nh\u1eadt.<\/p>\n<p><strong><em>*L\u01b0u \u00fd:<\/em><\/strong><\/p>\n<p><strong><em>C\u00e1c th\u00f4ng tin v\u1ec1 thu\u1ed1c tr\u00ean Pharmog.com ch\u1ec9 mang t\u00ednh ch\u1ea5t tham kh\u1ea3o &#8211; Khi d\u00f9ng thu\u1ed1c c\u1ea7n tuy\u1ec7t \u0111\u1ed1i tu\u00e2n theo theo h\u01b0\u1edbng d\u1eabn c\u1ee7a B\u00e1c s\u0129 <\/em><\/strong><\/p>\n<p><strong><em>Ch\u00fang t\u00f4i kh\u00f4ng ch\u1ecbu tr\u00e1ch nhi\u1ec7m v\u1ec1 b\u1ea5t c\u1ee9 h\u1eadu qu\u1ea3 n\u00e0o x\u1ea3y ra do t\u1ef1 \u00fd d\u00f9ng thu\u1ed1c d\u1ef1a theo c\u00e1c th\u00f4ng tin tr\u00ean Pharmog.com<\/em><\/strong><\/p>\n<p><script src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-5528370293090692\" async=\"\" crossorigin=\"anonymous\"><\/script><ins class=\"adsbygoogle\" style=\"display: block; text-align: center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-5528370293090692\" data-ad-slot=\"8909623906\"><\/ins><script> (adsbygoogle = window.adsbygoogle || []).push({}); <\/script><\/p>\n<p><strong>6. Ph\u1ea7n th\u00f4ng tin k\u00e8m theo c\u1ee7a thu\u1ed1c:<\/strong><\/p>\n<p><strong>6.1. Danh m\u1ee5c t\u00e1 d\u01b0\u1ee3c:<\/strong><\/p>\n<p>Microcrystalline cellulose (E460), Calcium hydrogen phosphate, anhydrous, Maize starch, Polacrilin potassium, Povidone (polyvidone), Glycerol 85%, Magnesium stearate, Meglumine, Poloxamer, Iron oxide, yellow (1 mg tablets only) (E172).<\/p>\n<p><strong>6.2. T\u01b0\u01a1ng k\u1ef5 :<\/strong><\/p>\n<p>Kh\u00f4ng \u00e1p d\u1ee5ng.<\/p>\n<p><strong>6.3. B\u1ea3o qu\u1ea3n: <\/strong><\/p>\n<p>N\u01a1i kh\u00f4, tr\u00e1nh \u00e1nh s\u00e1ng, nhi\u1ec7t \u0111\u1ed9 d\u01b0\u1edbi 30\u00b0C.<\/p>\n<p><strong>6.4. Th\u00f4ng tin kh\u00e1c :<\/strong><\/p>\n<p>Kh\u00f4ng c\u00f3.<\/p>\n<p><strong>6.5 T\u00e0i li\u1ec7u tham kh\u1ea3o:<\/strong><\/p>\n<p>D\u01b0\u1ee3c Th\u01b0 Qu\u1ed1c Gia Vi\u1ec7t Nam<\/p>\n<p>Ho\u1eb7c HDSD Thu\u1ed1c.<\/p>\n<p><strong>7. Ng\u01b0\u1eddi \u0111\u0103ng t\u1ea3i \/T\u00e1c gi\u1ea3:<\/strong><\/p>\n<p>B\u00e0i vi\u1ebft \u0111\u01b0\u1ee3c s\u01b0u t\u1ea7m ho\u1eb7c vi\u1ebft b\u1edfi: <a href=\"https:\/\/pharmog.com\/wp\/thong-tin-tac-gia-bac-sy-do-my-linh\/\">B\u00e1c s\u0129 nhi khoa &#8211; \u0110\u1ed7 M\u1ef9 Linh.<\/a><\/p>\n<p>Ki\u1ec3m duy\u1ec7t , hi\u1ec7u \u0111\u00ednh v\u00e0 \u0111\u0103ng t\u1ea3i: <a href=\"https:\/\/pharmog.com\/wp\/thong-tin-ve-pharmog-team\/\">PHARMOG TEAM<\/a><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Pranstad l\u00e0 thu\u1ed1c g\u00ec ? D\u01b0\u1edbi \u0111\u00e2y l\u00e0 n\u1ed9i dung t\u1edd h\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng g\u1ed1c c\u1ee7a Thu\u1ed1c Pranstad (Th\u00f4ng tin bao g\u1ed3m li\u1ec1u d\u00f9ng, c\u00e1ch d\u00f9ng, ch\u1ec9 \u0111\u1ecbnh, ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh, th\u1eadn tr\u1ecdng, d\u01b0\u1ee3c l\u00fd&#8230;) 1. T\u00ean ho\u1ea1t ch\u1ea5t v\u00e0 bi\u1ec7t d\u01b0\u1ee3c: Ho\u1ea1t ch\u1ea5t : Repaglinide Ph\u00e2n lo\u1ea1i: Thu\u00f4\u0301c \u0111i\u00ea\u0300u tri\u0323 ti\u00ea\u0309u \u0111\u01b0\u01a1\u0300ng. [&hellip;]<\/p>\n","protected":false},"author":8612,"featured_media":29408,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[419],"tags":[1133],"class_list":["post-29407","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-biet-duoc","tag-repaglinide"],"_links":{"self":[{"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/posts\/29407","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/users\/8612"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/comments?post=29407"}],"version-history":[{"count":3,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/posts\/29407\/revisions"}],"predecessor-version":[{"id":46328,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/posts\/29407\/revisions\/46328"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/media\/29408"}],"wp:attachment":[{"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/media?parent=29407"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/categories?post=29407"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/tags?post=29407"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}