{"id":28656,"date":"2021-01-31T19:21:31","date_gmt":"2021-01-31T12:21:31","guid":{"rendered":"https:\/\/pharmog.com\/wp\/?p=28656"},"modified":"2025-01-08T11:52:25","modified_gmt":"2025-01-08T04:52:25","slug":"omeprazole-helinzole","status":"publish","type":"post","link":"https:\/\/pharmog.com\/wp\/omeprazole-helinzole\/","title":{"rendered":"Omeprazole &#8211; Helinzole"},"content":{"rendered":"<p><em>Thu\u1ed1c Helinzole l\u00e0 thu\u1ed1c g\u00ec ? D\u01b0\u1edbi \u0111\u00e2y l\u00e0 n\u1ed9i dung t\u1edd h\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng g\u1ed1c c\u1ee7a Thu\u1ed1c Helinzole (Th\u00f4ng tin bao g\u1ed3m li\u1ec1u d\u00f9ng, c\u00e1ch d\u00f9ng, ch\u1ec9 \u0111\u1ecbnh, ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh, th\u1eadn tr\u1ecdng, d\u01b0\u1ee3c l\u00fd&#8230;)<\/em><\/p>\n<p><strong>1. T\u00ean ho\u1ea1t ch\u1ea5t v\u00e0 bi\u1ec7t d\u01b0\u1ee3c: <\/strong><\/p>\n<p><strong><em>Ho\u1ea1t ch\u1ea5t :<\/em> <\/strong><a href=\"https:\/\/pharmog.com\/wp\/omeprazole\/\"><strong>Omeprazole<\/strong><\/a><\/p>\n<p><strong><em>Ph\u00e2n lo\u1ea1i: <\/em><\/strong><em>Thu\u00f4\u0301c \u01b0\u0301c ch\u00ea\u0301 b\u01a1m Proton. Thu\u1ed1c gi\u1ea3m ti\u1ebft acid d\u1ea1 d\u00e0y<\/em><\/p>\n<p><strong><em>Nh\u00f3m<\/em><\/strong> <strong><em>ph\u00e1p l\u00fd: <\/em><\/strong><em>Thu\u1ed1c k\u00ea \u0111\u01a1n ETC \u2013 (Ethical drugs, prescription drugs, Prescription only medicine)<\/em><\/p>\n<p><strong><em>M\u00e3 ATC<\/em><\/strong> (Anatomical Therapeutic Chemical): A02BC01.<\/p>\n<p><strong><em>Bi\u1ec7t d\u01b0\u1ee3c g\u1ed1c: <\/em><\/strong><a href=\"https:\/\/pharmog.com\/wp\/omeprazole-sodium-losec\/\">Losec<\/a><\/p>\n<p><strong><em>Bi\u1ec7t d\u01b0\u1ee3c:<\/em><\/strong> Helinzole<\/p>\n<p><strong><em>H\u00e3ng s\u1ea3n xu\u1ea5t <\/em><\/strong>: C\u00f4ng ty c\u1ed5 ph\u1ea7n SPM<\/p>\n<p><script src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-5528370293090692\" async=\"\" crossorigin=\"anonymous\"><\/script><ins class=\"adsbygoogle\" style=\"display: block; text-align: center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-5528370293090692\" data-ad-slot=\"8909623906\"><\/ins><script> (adsbygoogle = window.adsbygoogle || []).push({}); <\/script><\/p>\n<p><strong>2. D\u1ea1ng b\u00e0o ch\u1ebf &#8211; H\u00e0m l\u01b0\u1ee3ng: <\/strong><\/p>\n<p><strong><em>D\u1ea1ng thu\u1ed1c v\u00e0 h\u00e0m l\u01b0\u1ee3ng<\/em><\/strong><\/p>\n<p>Vi\u00ean nang 20 mg.<\/p>\n<p><strong><em>Thu\u1ed1c tham kh\u1ea3o:<\/em><\/strong><\/p>\n<table>\n<tbody>\n<tr>\n<td colspan=\"2\"><strong><em>HELINZOLE 20mg<\/em><\/strong><\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td colspan=\"3\"><em>M\u1ed7i vi\u00ean nang c\u1ee9ng c\u00f3 ch\u1ee9a:<\/em><\/td>\n<\/tr>\n<tr>\n<td>Omeprazole<\/td>\n<td>&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.<\/td>\n<td>20 mg<\/td>\n<\/tr>\n<tr>\n<td>T\u00e1 d\u01b0\u1ee3c<\/td>\n<td>&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.<\/td>\n<td>v\u1eeba \u0111\u1ee7 (Xem m\u1ee5c 6.1)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><img loading=\"lazy\" decoding=\"async\" width=\"725\" height=\"383\" class=\"wp-image-28662\" src=\"https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2021\/01\/word-image-550.png\" srcset=\"https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2021\/01\/word-image-550.png 725w, https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2021\/01\/word-image-550-300x158.png 300w\" sizes=\"auto, (max-width: 725px) 100vw, 725px\" \/><\/p>\n<p><strong>3. Video by Pharmog:<\/strong><\/p>\n<p><strong>[VIDEO D\u01af\u1ee2C L\u00dd]<\/strong><\/p>\n<div class=\"ast-oembed-container \" style=\"height: 100%;\"><iframe loading=\"lazy\" title=\"[Pharmog SS1 - T\u1eadp 15] - D\u01b0\u1ee3c l\u00fd c\u00e1c thu\u1ed1c \u0111i\u1ec1u tr\u1ecb vi\u00eam lo\u00e9t d\u1ea1 d\u00e0y t\u00e1 tr\u00e0ng\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/wgt47Xu6X-4?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe><\/div>\n<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<\/p>\n<p>\u25ba K\u1ecbch B\u1ea3n: PharmogTeam<\/p>\n<p>\u25ba Youtube: https:\/\/www.youtube.com\/c\/pharmog<\/p>\n<p>\u25ba Facebook: https:\/\/www.facebook.com\/pharmog\/<\/p>\n<p>\u25ba Group : H\u1ed9i nh\u1eefng ng\u01b0\u1eddi m\u00ea d\u01b0\u1ee3c l\u00fd<\/p>\n<p>\u25ba Instagram : https:\/\/www.instagram.com\/pharmogvn\/<\/p>\n<p>\u25ba Website: pharmog.com<\/p>\n<p><strong>4. \u1ee8ng d\u1ee5ng l\u00e2m s\u00e0ng: <\/strong><\/p>\n<p><strong>4.1. Ch\u1ec9 \u0111\u1ecbnh:<\/strong><\/p>\n<p>\u0110i\u1ec1u tr\u1ecb vi\u00eam lo\u00e9t d\u1ea1 d\u00e0y, t\u00e1 tr\u00e0ng, vi\u00eam th\u1ef1c qu\u1ea3n do tr\u00e0o ng\u01b0\u1ee3c, h\u1ed9i ch\u1ee9ng t\u0103ng ti\u1ebft acid d\u1ecbch v\u1ecb (Zollinger &#8211; Ellinson).<\/p>\n<p><strong>4.2. Li\u1ec1u d\u00f9ng &#8211; C\u00e1ch d\u00f9ng:<\/strong><\/p>\n<p><strong><em>C\u00e1ch d\u00f9ng<\/em><\/strong> :<\/p>\n<p>D\u00f9ng u\u1ed1ng tr\u01b0\u1edbc b\u1eefa \u0103n s\u00e1ng ho\u1eb7c bu\u1ed5i t\u1ed1i, nu\u1ed1t nguy\u00ean vi\u00ean thu\u1ed1c, kh\u00f4ng d\u1eebng thu\u1ed1c \u0111\u1ed9t ng\u1ed9t.<\/p>\n<p><strong><em>Li\u1ec1u d\u00f9ng:<\/em><\/strong><\/p>\n<p><em>B\u1ec7nh nh\u00e2n vi\u00eam lo\u00e9t d\u1ea1 d\u00e0y, t\u00e1 tr\u00e0ng, v\u00e0 vi\u00eam th\u1ef1c qu\u1ea3n do tr\u00e0o ng\u01b0\u1ee3c:<\/em>\u00a0u\u1ed1ng l\u1ea7n 1 vi\u00ean (20mg), ng\u00e0y 1 l\u1ea7n.<\/p>\n<p>\u1ede b\u1ec7nh nh\u00e2n vi\u00eam lo\u00e9t t\u00e1 tr\u00e0ng: u\u1ed1ng li\u00ean t\u1ee5c trong th\u1eddi gian 2 tu\u1ea7n. N\u1ebfu ch\u01b0a kh\u1ecfi h\u1eb3n, u\u1ed1ng th\u00eam 2 tu\u1ea7n n\u1eefa.<\/p>\n<p>\u1ede b\u1ec7nh nh\u00e2n vi\u00eam lo\u00e9t d\u1ea1 d\u00e0y v\u00e0 vi\u00eam th\u1ef1c qu\u1ea3n do tr\u00e0o ng\u01b0\u1ee3c: u\u1ed1ng li\u00ean t\u1ee5c trong th\u1eddi gian 4 tu\u1ea7n. N\u1ebfu ch\u01b0a kh\u1ecfi h\u1eb3n, u\u1ed1ng th\u00eam 4 tu\u1ea7n n\u1eefa. V\u1edbi nh\u1eefng b\u1ec7nh nh\u00e2n vi\u00eam lo\u00e9t d\u1ea1 d\u00e0y, t\u00e1 tr\u00e0ng, vi\u00eam th\u1ef1c qu\u1ea3n do tr\u00e0o ng\u01b0\u1ee3c tr\u1ea7m tr\u1ecdng v\u00e0 \u0111\u1ec1 kh\u00e1ng v\u1edbi nh\u1eefng thu\u1ed1c kh\u00e1c: u\u1ed1ng 2 vi\u00ean 1 l\u1ea7n (40mg), ng\u00e0y u\u1ed1ng 1 l\u1ea7n. U\u1ed1ng li\u00ean t\u1ee5c trong 4 &#8211; 8 tu\u1ea7n.<\/p>\n<p><em>H\u1ed9i ch\u1ee9ng t\u0103ng ti\u1ebft acid d\u1ecbch v\u1ecb (Zollinger &#8211; Ellison):<\/em><\/p>\n<p>Li\u1ec1u kh\u1edfi \u0111\u1ea7u 3 vi\u00ean Omeprazol (60mg), u\u1ed1ng 1 l\u1ea7n m\u1ed7i ng\u00e0y.<\/p>\n<p>\u1ede b\u1ec7nh nh\u00e2n tr\u1ea7m tr\u1ecdng v\u00e0 kh\u00f4ng \u0111\u00e1p \u1ee9ng \u0111\u1ea7y \u0111\u1ee7 v\u1edbi nh\u1eefng thu\u1ed1c kh\u00e1c: u\u1ed1ng li\u1ec1u duy tr\u00ec 1 &#8211; 3 vi\u00ean m\u1ed7i l\u1ea7n (20mg &#8211; 60mg). Ng\u00e0y u\u1ed1ng 1 &#8211; 2 l\u1ea7n.<\/p>\n<p>\u0110i\u1ec1u tr\u1ecb h\u1ed9i ch\u1ee9ng Zollinger &#8211; Ellison: n\u1ebfu d\u00f9ng li\u1ec1u tr\u00ean 80mg th\u00ec chia ra 2 l\u1ea7n\/ng\u00e0y.<\/p>\n<p><strong>4.3. Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh:<\/strong><\/p>\n<p>Qu\u00e1 m\u1eabn c\u1ea3m v\u1edbi b\u1ea5t c\u1ee9 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/p>\n<p>Kh\u00f4ng d\u00f9ng cho ph\u1ee5 n\u1eef c\u00f3 thai 3 th\u00e1ng \u0111\u1ea7u.<\/p>\n<p><strong>4.4 Th\u1eadn tr\u1ecdng:<\/strong><\/p>\n<p>Khi nghi ng\u1edd lo\u00e9t d\u1ea1 d\u00e0y, mu\u1ed1n d\u00f9ng Omeprazol, tr\u01b0\u1edbc h\u1ebft ph\u1ea3i lo\u1ea1i tr\u1eeb kh\u1ea3 n\u0103ng b\u1ec7nh \u00e1c t\u00ednh v\u00ec \u0111i\u1ec1u tr\u1ecb c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m tri\u1ec7u ch\u1ee9ng v\u00e0 g\u00e2y tr\u1edf ng\u1ea1i cho ch\u1ea9n \u0111o\u00e1n.<\/p>\n<p>Trong th\u1eddi k\u1ef3 mang thai v\u00e0 cho con b\u00fa, c\u1ea7n thi\u1ebft ph\u1ea3i c\u00f3 ch\u1ec9 \u0111\u1ecbnh c\u1ee7a th\u1ea7y thu\u1ed1c.<\/p>\n<p><strong>T\u00e1c \u0111\u1ed9ng c\u1ee7a thu\u1ed1c tr\u00ean ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/strong><\/p>\n<p>Kh\u00f4ng n\u00ean d\u00f9ng Omeprazol khi \u0111ang v\u1eadn h\u00e0nh m\u00e1y m\u00f3c, t\u00e0u xe v\u00ec thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y ch\u00f3ng m\u1eb7t, bu\u1ed3n ng\u1ee7.<\/p>\n<p><strong>4.5 S\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa:<\/strong><\/p>\n<p><em>X\u1ebfp h\u1ea1ng c\u1ea3nh b\u00e1o<\/em><\/p>\n<p>AU TGA pregnancy category: B3<\/p>\n<p>US FDA pregnancy category: NA<\/p>\n<p><em>Th\u1eddi k\u1ef3 mang thai:<\/em><\/p>\n<p>Tuy tr\u00ean th\u1ef1c nghi\u1ec7m kh\u00f4ng th\u1ea5y omeprazol c\u00f3 kh\u1ea3 n\u0103ng g\u00e2y d\u1ecb d\u1ea1ng v\u00e0 \u0111\u1ed9c v\u1edbi b\u00e0o thai, nh\u01b0ng kh\u00f4ng n\u00ean d\u00f9ng cho ng\u01b0\u1eddi mang thai, nh\u1ea5t l\u00e0 trong 3 th\u00e1ng \u0111\u1ea7u.<\/p>\n<p><em>Th\u1eddi k\u1ef3 cho con b\u00fa:<\/em><\/p>\n<p>Kh\u00f4ng n\u00ean d\u00f9ng omeprazol \u1edf ng\u01b0\u1eddi cho con b\u00fa. Cho \u0111\u1ebfn nay, ch\u01b0a t\u00e0i li\u1ec7u nghi\u00ean c\u1ee9u n\u00e0o c\u00f3 k\u1ebft lu\u1eadn c\u1ee5 th\u1ec3 v\u1ec1 v\u1ea5n \u0111\u1ec1 n\u00e0y.<\/p>\n<p><strong>4.6 T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n (ADR):<\/strong><\/p>\n<p><em>Th\u01b0\u1eddng g\u1eb7p, ADR &gt; 1\/100.<\/em><\/p>\n<p>To\u00e0n th\u00e2n: Nh\u1ee9c \u0111\u1ea7u, bu\u1ed3n ng\u1ee7, ch\u00f3ng m\u1eb7t.<\/p>\n<p>Ti\u00eau h\u00f3a: \u1ec8a ch\u1ea3y, bu\u1ed3n n\u00f4n, n\u00f4n, \u0111au b\u1ee5ng, t\u00e1o b\u00f3n, tr\u01b0\u1edbng b\u1ee5ng.<\/p>\n<p><em>\u00cdt g\u1eb7p, 1\/1 000 &lt; ADR&lt;1\/100<\/em><\/p>\n<p>Th\u1ea7n kinh: M\u1ea5t ng\u1ee7, r\u1ed1i lo\u1ea1n c\u1ea3m gi\u00e1c, m\u1ec7t m\u1ecfi.<\/p>\n<p>Da: M\u00e0y \u0111ay, ng\u1ee9a. n\u1ed5i ban.<\/p>\n<p>Gan: T\u0103ng transaminase nh\u1ea5t th\u1eddi.<\/p>\n<p><em>Hi\u1ebfm g\u1eb7p, ADR &lt; 1\/1 000<\/em><\/p>\n<p>To\u00e0n th\u00e2n: \u0110\u1ed5 m\u1ed3 h\u00f4i, ph\u00f9 ngo\u1ea1i bi\u00ean, qu\u00e1 m\u1eabn bao g\u1ed3m ph\u00f9 m\u1ea1ch, s\u1ed1t ph\u1ea3n v\u1ec7.<\/p>\n<p>Huy\u1ebft h\u1ecdc: Gi\u1ea3m b\u1ea1ch c\u1ea7u, gi\u1ea3m ti\u1ebfu c\u1ea7u, gi\u1ea3m to\u00e0n b\u1ed9 c\u00e1c d\u00f2ng t\u1ebf b\u00e0o m\u00e1u, m\u1ea5t b\u1ea1ch c\u1ea7u h\u1ea1t, thi\u1ebfu m\u00e1u t\u00e1n huy\u1ebft t\u1ef1 mi\u1ec5n.<\/p>\n<p>Th\u1ea7n kinh: L\u00fa l\u1eabn c\u00f3 h\u1ed3i ph\u1ee5c, k\u00edch \u0111\u1ed9ng, tr\u1ea7m c\u1ea3m, \u1ea3o gi\u00e1c \u1edf ng\u01b0\u1eddi b\u1ec7nh cao tu\u1ed5i v\u00e0 \u0111\u1eb7c bi\u1ec7t \u1edf ng\u01b0\u1eddi b\u1ec7nh n\u1eb7ng, r\u1ed1i lo\u1ea1n th\u00ednh gi\u00e1c.<\/p>\n<p>N\u1ed9i ti\u1ebft: V\u00fa to \u1edf \u0111\u00e0n \u00f4ng.<\/p>\n<p>Ti\u00eau h\u00f3a: Vi\u00eam d\u1ea1 d\u00e0y, nhi\u1ec5m n\u1ea5m <em>Candida,<\/em> kh\u00f4 mi\u1ec7ng.<\/p>\n<p>Gan: Vi\u00eam gan k\u00e8m v\u00e0ng da ho\u1eb7c kh\u00f4ng v\u00e0ng da, b\u1ec7nh n\u00e3o &#8211; gan \u1edf ng\u01b0\u1eddi suy gan.<\/p>\n<p>H\u00f4 h\u1ea5p: Co th\u1eaft ph\u1ebf qu\u1ea3n.<\/p>\n<p>C\u01a1 &#8211; x\u01b0\u01a1ng: \u0110au kh\u1edbp, \u0111au c\u01a1.<\/p>\n<p>Ti\u1ebft ni\u1ec7u, sinh d\u1ee5c: Vi\u00eam th\u1eadn k\u1ebd.<\/p>\n<p><em>Th\u00f4ng b\u00e1o cho B\u00e1c s\u0129 nh\u1eefng t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n g\u1eb7p ph\u1ea3i khi s\u1eed d\u1ee5ng thu\u1ed1c.<\/em><\/p>\n<p><script src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-5528370293090692\" async=\"\" crossorigin=\"anonymous\"><\/script><ins class=\"adsbygoogle\" style=\"display: block; text-align: center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-5528370293090692\" data-ad-slot=\"8909623906\"><\/ins><script> (adsbygoogle = window.adsbygoogle || []).push({}); <\/script><\/p>\n<p><strong>4.7 H\u01b0\u1edbng d\u1eabn c\u00e1ch x\u1eed tr\u00ed ADR:<\/strong><\/p>\n<p>Ph\u1ea3i ng\u1eebng thu\u1ed1c khi c\u00f3 bi\u1ebfu hi\u1ec7n t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n n\u1eb7ng . V\u1edbi c\u00e1c ph\u1ea3n \u1ee9ng b\u1ea5t l\u1ee3i nh\u1eb9, th\u01b0\u1eddng ch\u1ec9 c\u1ea7n ng\u1eebng thu\u1ed1c. Tr\u01b0\u1eddng h\u1ee3p m\u1eabn c\u1ea3m n\u1eb7ng ho\u1eb7c ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng, c\u1ea7n ti\u1ebfn h\u00e0nh \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3 (gi\u1eef tho\u00e1ng kh\u00ed v\u00e0 d\u00f9ng epinephrin, th\u1edf oxygen, d\u00f9ng kh\u00e1ng histamin, corticoid&#8230;).<\/p>\n<p><strong>4.8 T\u01b0\u01a1ng t\u00e1c v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1c:<\/strong><\/p>\n<p>Omeprazol kh\u00f4ng c\u00f3 t\u01b0\u01a1ng t\u00e1c quan tr\u1ecdng tr\u00ean l\u00e2m s\u00e0ng khi \u0111\u01b0\u1ee3c d\u00f9ng c\u00f9ng th\u1ee9c \u0103n, r\u01b0\u1ee3u, amoxycilin, bacampicilin, cafein, lidocain, quinidin hay theophylin. Thu\u1ed1c c\u0169ng kh\u00f4ng b\u1ecb \u1ea3nh h\u01b0\u1edfng do d\u00f9ng \u0111\u1ed3ng th\u1eddi Maalox hay metoclopramid.<\/p>\n<p>Omeprazol c\u00f3 th\u1ec3 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 ciclosporin trong m\u00e1u.<\/p>\n<p>Omeprazol l\u00e0m t\u0103ng t\u00e1c d\u1ee5ng c\u1ee7a kh\u00e1ng sinh di\u1ec7t tr\u1eeb H. pylori.<\/p>\n<p>Kh\u00f4ng c\u00f3 t\u01b0\u01a1ng t\u00e1c n\u00e0o ghi nh\u1eadn v\u1edbi propranolon ho\u1eb7c theophylin.<\/p>\n<p>Omeprazol \u1ee9c ch\u1ebf chuy\u1ec3n h\u00f3a c\u1ee7a c\u00e1c thu\u1ed1c b\u1ecb chuy\u1ec3n h\u00f3a b\u1edfi h\u1ec7 enzym trong cytocrom P450 c\u1ee7a gan v\u00e0 c\u00f3 th\u1ec3 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 diazepam, phenytoin v\u00e0 warfarin trong m\u00e1u. S\u1ef1 gi\u1ea3m chuy\u1ec3n h\u00f3a c\u1ee7a diazepam l\u00e0m cho t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c k\u00e9o d\u00e0i h\u01a1n. V\u1edbi li\u1ec1u 40mg\/ng\u00e0y omeprazol \u1ee9c ch\u1ebf chuy\u1ec3n h\u00f3a phenytoin v\u00e0 l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 c\u1ee7a phenytoin trong m\u00e1u, nh\u01b0ng li\u1ec1u omeprazol 20mg\/ng\u00e0y l\u1ea1i c\u00f3 t\u01b0\u01a1ng t\u00e1c y\u1ebfu h\u01a1n nhi\u1ec1u. Omeprazol \u1ee9c ch\u1ebf chuy\u1ec3n h\u00f3a warfarin, nh\u01b0ng l\u1ea1i \u00edt l\u00e0m thay \u0111\u1ed5i th\u1eddi gian ch\u1ea3y m\u00e1u.<\/p>\n<p>Omeprazol l\u00e0m t\u0103ng t\u00e1c d\u1ee5ng ch\u1ed1ng \u0111\u00f4ng m\u00e1u c\u1ee7a dicoumarol.<\/p>\n<p>Omeprazol l\u00e0m gi\u1ea3m chuy\u1ec3n h\u00f3a nifedipin \u00edt nh\u1ea5t l\u00e0 20% v\u00e0 c\u00f3 th\u1ec3 l\u00e0m t\u0103ng t\u00e1c d\u1ee5ng c\u1ee7a nifedipin.<\/p>\n<p>Clarithromycin \u1ee9c ch\u1ebf chuy\u1ec3n h\u00f3a omeprazol v\u00e0 l\u00e0m cho n\u1ed3ng \u0111\u1ed9 omeprazol t\u0103ng cao g\u1ea5p \u0111\u00f4i.<\/p>\n<p><strong>4.9 Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed:<\/strong><\/p>\n<p>Li\u1ec1u u\u1ed1ng m\u1ed9t l\u1ea7n t\u1edbi 160mg, li\u1ec1u ti\u00eam t\u0129nh m\u1ea1ch m\u1ed9t l\u1ea7n t\u1edbi 80mg, li\u1ec1u ti\u00eam t\u0129nh m\u1ea1ch m\u1ed9t ng\u00e0y t\u1edbi 200mg v\u00e0 li\u1ec1u 520mg ti\u00eam t\u0129nh m\u1ea1ch trong th\u1eddi gian 3 ng\u00e0y v\u1eabn \u0111\u01b0\u1ee3c dung n\u1ea1p t\u1ed1t.<\/p>\n<p>Khi u\u1ed1ng qu\u00e1 li\u1ec1u, ph\u1ea3i \u0111i\u1ec1u tr\u1ecb theo tri\u1ec7u ch\u1ee9ng, kh\u00f4ng c\u00f3 thu\u1ed1c \u0111i\u1ec1u tr\u1ecb \u0111\u1eb7c hi\u1ec7u.<\/p>\n<p>Th\u00f4ng b\u00e1o ngay cho b\u00e1c s\u1ef9 nh\u1eefng t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n g\u1eb7p ph\u1ea3i khi s\u1eed d\u1ee5ng thu\u1ed1c qu\u00e1 li\u1ec1u.<\/p>\n<p><strong>5. C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c :<\/strong><\/p>\n<p><strong>5.1. D\u01b0\u1ee3c l\u1ef1c h\u1ecdc:<\/strong><\/p>\n<p>Omeprazol thu\u1ed9c nh\u00f3m c\u00e1c h\u1ee3p ch\u1ea5t ch\u1ed1ng ti\u1ebft th\u1ebf h\u1ec7 m\u1edbi, c\u00f3 t\u00e1c d\u1ee5ng ng\u0103n ch\u1eb7n ti\u1ebft acid d\u1ea1 d\u00e0y b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf \u0111\u1eb7c hi\u1ec7u h\u1ec7 th\u1ed1ng enzyme H+\/K+ ATPase t\u1ea1i m\u1eb7t ti\u1ebft c\u1ee7a t\u1ebf b\u00e0o th\u00e0nh d\u1ea1 d\u00e0y.<\/p>\n<p>Omeprazol \u0111\u01b0\u1ee3c m\u00f4 t\u1ea3 nh\u01b0 m\u1ed9t ch\u1ea5t \u1ee9c ch\u1ebf b\u01a1m acid d\u1ea1 d\u00e0y, phong t\u1ecfa giai \u0111o\u1ea1n cu\u1ed1i c\u00f9ng c\u1ee7a s\u1ef1 s\u1ea3n xu\u1ea5t acid. T\u00e1c d\u1ee5ng n\u00e0y c\u00f3 li\u00ean quan \u0111\u1ebfn li\u1ec1u d\u00f9ng, d\u1eabn \u0111\u1ebfn \u1ee9c ch\u1ebf c\u1ea3 s\u1ef1 ti\u1ebft acid c\u01a1 b\u1ea3n l\u1eabn s\u1ef1 ti\u1ebft acid k\u00edch th\u00edch b\u1ea5t k\u1ec3 do t\u00e1c nh\u00e2n k\u00edch th\u00edch n\u00e0o.<\/p>\n<p><strong><em>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng: <\/em><\/strong><\/p>\n<p>Omeprazol thu\u1ed9c nh\u00f3m h\u1ee3p ch\u1ea5t \u1ee9c ch\u1ebf s\u1ef1 b\u00e0i ti\u1ebft th\u1ebf h\u1ec7 m\u1edbi, d\u1eabn xu\u1ea5t c\u1ee7a benzimidazol, thu\u1ed1c kh\u00f4ng c\u00f3 ho\u1ea1t t\u00ednh kh\u00e1ng cholinergic hay kh\u00e1ng th\u1ee5 th\u1ec3 H2\u00a0c\u1ee7a histamin, m\u00e0 \u1ee9c ch\u1ebf s\u1ef1 b\u00e0i ti\u1ebft acid d\u1ea1 d\u00e0y b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf chuy\u00ean bi\u1ec7t h\u1ec7 th\u1ed1ng enzym H+\/ K+ ATPase t\u1ea1i b\u1ec1 m\u1eb7t b\u00e0i ti\u1ebft c\u1ee7a t\u1ebf b\u00e0o th\u00e0nh d\u1ea1 d\u00e0y. V\u00ec h\u1ec7 th\u1ed1ng enzym n\u00e0y \u0111\u01b0\u1ee3c xem nh\u01b0 l\u00e0 b\u01a1m acid (proton) \u1edf ni\u00eam m\u1ea1c d\u1ea1 d\u00e0y, omeprazol \u0111\u01b0\u1ee3c xem nh\u01b0 m\u1ed9t ch\u1ea5t \u1ee9c ch\u1ebf b\u01a1m acid c\u1ee7a d\u1ea1 d\u00e0y, ng\u0103n ch\u1eb7n b\u01b0\u1edbc cu\u1ed1i c\u00f9ng c\u1ee7a s\u1ef1 s\u1ea3n sinh acid. T\u00e1c d\u1ee5ng n\u00e0y li\u00ean quan \u0111\u1ebfn li\u1ec1u d\u00f9ng v\u00e0 d\u1eabn \u0111\u1ebfn \u1ee9c ch\u1ebf c\u1ea3 c\u01a1 ch\u1ebf ti\u1ebft acid c\u01a1 b\u1ea3n v\u00e0 ti\u1ebft acid khi b\u1ecb k\u00edch th\u00edch do b\u1ea5t k\u1ef3 t\u00e1c nh\u00e2n k\u00edch th\u00edch n\u00e0o.<\/p>\n<p><a href=\"https:\/\/www.youtube.com\/watch?v=wgt47Xu6X-4\"><strong>[XEM T\u1ea0I \u0110\u00c2Y]<\/strong><\/a><\/p>\n<p><strong>5.2. D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc:<\/strong><\/p>\n<p>Ho\u1ea1t t\u00ednh ch\u1ed1ng ti\u1ebft: sau khi u\u1ed1ng thu\u1ed1c, t\u00e1c d\u1ee5ng ch\u1ed1ng ti\u1ebft b\u1eaft \u0111\u1ea7u xu\u1ea5t hi\u1ec7n trong v\u00f2ng 1 gi\u1edd, hi\u1ec7u qu\u1ea3 t\u1ed1i \u0111a \u0111\u1ea1t \u0111\u01b0\u1ee3c sau 2 gi\u1edd. S\u1ef1 \u1ee9c ch\u1ebf ti\u1ebft c\u00f2n kho\u1ea3ng 50% sau 24 gi\u1edd v\u00e0 th\u1eddi gian \u1ee9c ch\u1ebf k\u00e9o d\u00e0i \u0111\u1ebfn 72 gi\u1edd. Do \u0111\u00f3 t\u00e1c d\u1ee5ng ch\u1ed1ng ti\u1ebft t\u1ed3n t\u1ea1i l\u00e2u h\u01a1n, d\u00f9 th\u1eddi gian b\u00e1n h\u1ee7y ng\u1eafn. Hi\u1ec7u qu\u1ea3 \u1ee9c ch\u1ebf ti\u1ebft acid c\u1ee7a Omeprazol gia t\u0103ng sau khi d\u00f9ng li\u00ean t\u1ee5c li\u1ec1u duy nh\u1ea5t m\u1ed7i ng\u00e0y, li\u1ec1u d\u00f9ng th\u00f4ng th\u01b0\u1eddng \u0111\u1ea1t hi\u1ec7u qu\u1ea3 sau 6 ng\u00e0y.<\/p>\n<p>Helinzole ch\u1ee9a Omeprazol \u0111\u01b0\u1ee3c b\u00e0o ch\u1ebf d\u01b0\u1edbi d\u1ea1ng vi h\u1ea1t tan trong ru\u1ed9t (v\u00ec Omeprazol b\u1ecb ph\u00e2n h\u1ee7y trong m\u00f4i tr\u01b0\u1eddng acid). Thu\u1ed1c \u0111\u01b0\u1ee3c h\u1ea5p thu nhanh, \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng \u0111\u1ea1t \u0111\u01b0\u1ee3c trong v\u00f2ng t\u1eeb 0.5 \u0111\u1ebfn 3.5 gi\u1edd. Sinh kh\u1ea3 d\u1ee5ng tuy\u1ec7t \u0111\u1ed1i kho\u1ea3ng 30 \u2013 40% \u1edf li\u1ec1u 20 \u2013 40mg ch\u1ee7 y\u1ebfu do c\u01a1 ch\u1ebf chuy\u1ec3n ho\u00e1 ti\u1ec1n h\u1ec7 th\u1ed1ng.<\/p>\n<p>Th\u1eddi gian b\u00e1n h\u1ee7y trong huy\u1ebft t\u01b0\u01a1ng kho\u1ea3ng t\u1eeb 0.5 \u0111\u1ebfn 1 gi\u1edd v\u00e0 kho\u1ea3ng 90% li\u00ean k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng. Ph\u1ea7n l\u1edbn li\u1ec1u d\u00f9ng (kho\u1ea3ng 77%) \u0111\u01b0\u1ee3c \u0111\u00e0o th\u1ea3i qua n\u01b0\u1edbc ti\u1ec3u d\u01b0\u1edbi d\u1ea1ng \u00edt nh\u1ea5t 6 ch\u1ea5t chuy\u1ec3n ho\u00e1.<\/p>\n<p><strong>5.3 Gi\u1ea3i th\u00edch: <\/strong><\/p>\n<p>Ch\u01b0a c\u00f3 th\u00f4ng tin. \u0110ang c\u1eadp nh\u1eadt.<\/p>\n<p><strong>5.4 Thay th\u1ebf thu\u1ed1c : <\/strong><\/p>\n<p>Ch\u01b0a c\u00f3 th\u00f4ng tin. \u0110ang c\u1eadp nh\u1eadt.<\/p>\n<p><strong><em>*L\u01b0u \u00fd:<\/em><\/strong><\/p>\n<p><strong><em>C\u00e1c th\u00f4ng tin v\u1ec1 thu\u1ed1c tr\u00ean Pharmog.com ch\u1ec9 mang t\u00ednh ch\u1ea5t tham kh\u1ea3o &#8211; Khi d\u00f9ng thu\u1ed1c c\u1ea7n tuy\u1ec7t \u0111\u1ed1i tu\u00e2n theo theo h\u01b0\u1edbng d\u1eabn c\u1ee7a B\u00e1c s\u0129 <\/em><\/strong><\/p>\n<p><strong><em>Ch\u00fang t\u00f4i kh\u00f4ng ch\u1ecbu tr\u00e1ch nhi\u1ec7m v\u1ec1 b\u1ea5t c\u1ee9 h\u1eadu qu\u1ea3 n\u00e0o x\u1ea3y ra do t\u1ef1 \u00fd d\u00f9ng thu\u1ed1c d\u1ef1a theo c\u00e1c th\u00f4ng tin tr\u00ean Pharmog.com<\/em><\/strong><\/p>\n<p><script src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-5528370293090692\" async=\"\" crossorigin=\"anonymous\"><\/script><ins class=\"adsbygoogle\" style=\"display: block; text-align: center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-5528370293090692\" data-ad-slot=\"8909623906\"><\/ins><script> (adsbygoogle = window.adsbygoogle || []).push({}); <\/script><\/p>\n<p><strong>6. Ph\u1ea7n th\u00f4ng tin k\u00e8m theo c\u1ee7a thu\u1ed1c:<\/strong><\/p>\n<p><strong>6.1. Danh m\u1ee5c t\u00e1 d\u01b0\u1ee3c:<\/strong><\/p>\n<p><strong>6.2. T\u01b0\u01a1ng k\u1ef5 :<\/strong><\/p>\n<p>Kh\u00f4ng c\u00f3.<\/p>\n<p><strong>6.3. B\u1ea3o qu\u1ea3n: <\/strong><\/p>\n<p>N\u01a1i kh\u00f4, tr\u00e1nh \u00e1nh s\u00e1ng, nhi\u1ec7t \u0111\u1ed9 d\u01b0\u1edbi 30\u00b0C.<\/p>\n<p><strong>6.4. Th\u00f4ng tin kh\u00e1c :<\/strong><\/p>\n<p>Kh\u00f4ng c\u00f3.<\/p>\n<p><strong>6.5 T\u00e0i li\u1ec7u tham kh\u1ea3o:<\/strong><\/p>\n<p>D\u01b0\u1ee3c Th\u01b0 Qu\u1ed1c Gia Vi\u1ec7t Nam<\/p>\n<p>Ho\u1eb7c HDSD Thu\u1ed1c.<\/p>\n<p><strong>7. Ng\u01b0\u1eddi \u0111\u0103ng t\u1ea3i \/T\u00e1c gi\u1ea3:<\/strong><\/p>\n<p>B\u00e0i vi\u1ebft \u0111\u01b0\u1ee3c s\u01b0u t\u1ea7m ho\u1eb7c vi\u1ebft b\u1edfi: <a href=\"https:\/\/pharmog.com\/wp\/thong-tin-tac-gia-bac-sy-do-my-linh\/\">B\u00e1c s\u0129 nhi khoa &#8211; \u0110\u1ed7 M\u1ef9 Linh.<\/a><\/p>\n<p>Ki\u1ec3m duy\u1ec7t , hi\u1ec7u \u0111\u00ednh v\u00e0 \u0111\u0103ng t\u1ea3i: <a href=\"https:\/\/pharmog.com\/wp\/thong-tin-ve-pharmog-team\/\">PHARMOG TEAM<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thu\u1ed1c Helinzole l\u00e0 thu\u1ed1c g\u00ec ? D\u01b0\u1edbi \u0111\u00e2y l\u00e0 n\u1ed9i dung t\u1edd h\u01b0\u1edbng d\u1eabn s\u1eed d\u1ee5ng g\u1ed1c c\u1ee7a Thu\u1ed1c Helinzole (Th\u00f4ng tin bao g\u1ed3m li\u1ec1u d\u00f9ng, c\u00e1ch d\u00f9ng, ch\u1ec9 \u0111\u1ecbnh, ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh, th\u1eadn tr\u1ecdng, d\u01b0\u1ee3c l\u00fd&#8230;) 1. T\u00ean ho\u1ea1t ch\u1ea5t v\u00e0 bi\u1ec7t d\u01b0\u1ee3c: Ho\u1ea1t ch\u1ea5t : Omeprazole Ph\u00e2n lo\u1ea1i: Thu\u00f4\u0301c \u01b0\u0301c ch\u00ea\u0301 b\u01a1m Proton. [&hellip;]<\/p>\n","protected":false},"author":8612,"featured_media":28662,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[419],"tags":[1107],"class_list":["post-28656","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-biet-duoc","tag-omeprazole"],"_links":{"self":[{"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/posts\/28656","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/users\/8612"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/comments?post=28656"}],"version-history":[{"count":3,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/posts\/28656\/revisions"}],"predecessor-version":[{"id":46552,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/posts\/28656\/revisions\/46552"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/media\/28662"}],"wp:attachment":[{"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/media?parent=28656"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/categories?post=28656"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/tags?post=28656"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}