{"id":22807,"date":"2020-09-17T16:31:25","date_gmt":"2020-09-17T09:31:25","guid":{"rendered":"https:\/\/pharmog.com\/wp\/?p=22807"},"modified":"2025-01-08T20:50:54","modified_gmt":"2025-01-08T13:50:54","slug":"esomeprazole-esovex","status":"publish","type":"post","link":"https:\/\/pharmog.com\/wp\/esomeprazole-esovex\/","title":{"rendered":"Esomeprazole &#8211; Esovex"},"content":{"rendered":"<p><strong>1. T\u00ean ho\u1ea1t ch\u1ea5t v\u00e0 bi\u1ec7t d\u01b0\u1ee3c: <\/strong><\/p>\n<p><strong><em>Ho\u1ea1t ch\u1ea5t :<\/em> <\/strong><a href=\"https:\/\/pharmog.com\/wp\/esomeprazole\/\"><strong>Esomeprazole<\/strong><\/a><\/p>\n<p><strong><em>Ph\u00e2n lo\u1ea1i: <\/em><\/strong><em>Thu\u00f4\u0301c \u01b0\u0301c ch\u00ea\u0301 b\u01a1m Proton.<\/em><\/p>\n<p><strong><em>Nh\u00f3m<\/em><\/strong> <strong><em>ph\u00e1p l\u00fd: <\/em><\/strong><em>Thu\u1ed1c k\u00ea \u0111\u01a1n ETC \u2013 (Ethical drugs, prescription drugs, Prescription only medicine)<\/em><\/p>\n<p><strong><em>M\u00e3 ATC<\/em><\/strong> (Anatomical Therapeutic Chemical): A02BC05.<\/p>\n<p><strong><em>Bi\u1ec7t d\u01b0\u1ee3c g\u1ed1c:<\/em><\/strong> <a href=\"https:\/\/pharmog.com\/wp\/esomeprazole-nexium-inj\/\">Nexium injection<\/a>, <a href=\"https:\/\/pharmog.com\/wp\/esomeprazole-nexium-mups\/\">Nexium Mups<\/a> , <a href=\"https:\/\/pharmog.com\/wp\/esomeprazole-nexium-sachet\/\">Nexium Sachet<\/a><\/p>\n<p><strong><em>Bi\u1ec7t d\u01b0\u1ee3c:<\/em><\/strong> Esovex<\/p>\n<p><strong><em>H\u00e3ng s\u1ea3n xu\u1ea5t <\/em><\/strong>: Naprod Life Sciences Pvt. Ltd.<\/p>\n<p><script src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-5528370293090692\" async=\"\" crossorigin=\"anonymous\"><\/script><ins class=\"adsbygoogle\" style=\"display: block; text-align: center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-5528370293090692\" data-ad-slot=\"8909623906\"><\/ins><script> (adsbygoogle = window.adsbygoogle || []).push({}); <\/script><\/p>\n<p><strong>2. D\u1ea1ng b\u00e0o ch\u1ebf &#8211; H\u00e0m l\u01b0\u1ee3ng: <\/strong><\/p>\n<p><strong><em>D\u1ea1ng thu\u1ed1c v\u00e0 h\u00e0m l\u01b0\u1ee3ng<\/em><\/strong><\/p>\n<p>B\u1ed9t \u0111\u00f4ng kh\u00f4 pha ti\u00eam 40mg.<\/p>\n<p><strong><em>Thu\u1ed1c tham kh\u1ea3o:<\/em><\/strong><\/p>\n<table>\n<tbody>\n<tr>\n<td colspan=\"2\"><strong><em>ESOVEX 40<\/em><\/strong><\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\"><em>M\u1ed7i l\u1ecd b\u1ed9t c\u00f3 ch\u1ee9a:<\/em><\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td>Esomeprazole<\/td>\n<td>&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.<\/td>\n<td>40 mg<\/td>\n<\/tr>\n<tr>\n<td>T\u00e1 d\u01b0\u1ee3c<\/td>\n<td>&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.<\/td>\n<td>v\u1eeba \u0111\u1ee7 (Xem m\u1ee5c 6.1)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><img loading=\"lazy\" decoding=\"async\" width=\"343\" height=\"397\" class=\"wp-image-22808\" src=\"https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2020\/09\/word-image-267.png\" srcset=\"https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2020\/09\/word-image-267.png 343w, https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2020\/09\/word-image-267-259x300.png 259w, https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2020\/09\/word-image-267-138x160.png 138w\" sizes=\"auto, (max-width: 343px) 100vw, 343px\" \/><\/p>\n<p><strong>3. Video by Pharmog:<\/strong><\/p>\n<p><strong>[VIDEO D\u01af\u1ee2C L\u00dd]<\/strong><\/p>\n<div class=\"ast-oembed-container \" style=\"height: 100%;\"><iframe loading=\"lazy\" title=\"[Pharmog SS1 - T\u1eadp 15] - D\u01b0\u1ee3c l\u00fd c\u00e1c thu\u1ed1c \u0111i\u1ec1u tr\u1ecb vi\u00eam lo\u00e9t d\u1ea1 d\u00e0y t\u00e1 tr\u00e0ng\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/wgt47Xu6X-4?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe><\/div>\n<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<\/p>\n<p>\u25ba K\u1ecbch B\u1ea3n: PharmogTeam<\/p>\n<p>\u25ba Youtube: https:\/\/www.youtube.com\/c\/pharmog<\/p>\n<p>\u25ba Facebook: https:\/\/www.facebook.com\/pharmog\/<\/p>\n<p>\u25ba Group : H\u1ed9i nh\u1eefng ng\u01b0\u1eddi m\u00ea d\u01b0\u1ee3c l\u00fd<\/p>\n<p>\u25ba Instagram : https:\/\/www.instagram.com\/pharmogvn\/<\/p>\n<p>\u25ba Website: pharmog.com<\/p>\n<p><strong>4. \u1ee8ng d\u1ee5ng l\u00e2m s\u00e0ng: <\/strong><\/p>\n<p><strong>4.1. Ch\u1ec9 \u0111\u1ecbnh:<\/strong><\/p>\n<p>Lo\u00e9t d\u1ea1 d\u00e0y &#8211; t\u00e1 tr\u00e0ng l\u00e0nh t\u00ednh.<\/p>\n<p>H\u1ed9i ch\u1ee9ng Zollinger-Ellison<\/p>\n<p>B\u1ec7nh tr\u00e0o ng\u01b0\u1ee3c d\u1ea1 d\u00e0y \u2013 th\u1ef1c qu\u1ea3n n\u1eb7ng (vi\u00eam th\u1ef1c qu\u1ea3n tr\u1ee3t x\u01b0\u1edbc, lo\u00e9t ho\u1eb7c th\u1eaft h\u1eb9p \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh b\u1eb1ng n\u1ed9i soi).<\/p>\n<p><strong>4.2. Li\u1ec1u d\u00f9ng &#8211; C\u00e1ch d\u00f9ng:<\/strong><\/p>\n<p><strong><em>C\u00e1ch d\u00f9ng<\/em><\/strong> :<\/p>\n<p>D\u00f9ng \u0111\u01b0\u1eddng ti\u00eam<\/p>\n<p>Ti\u00eam t\u0129nh m\u1ea1ch ch\u1eadm \u00edt nh\u1ea5t trong 3 ph\u00fat. Dung d\u1ecbch ti\u00eam \u0111\u01b0\u1ee3c pha ch\u1ebf b\u1eb1ng c\u00e1ch th\u00eam 5ml dung d\u1ecbch natri clorid 0,9%, d\u00f9ng \u0111\u01b0\u1eddng t\u0129nh m\u1ea1ch v\u00e0o l\u1ecd thu\u1ed1c ti\u00eam ch\u1ee9a esomeprazol. Dung d\u1ecbch ti\u00eam sau khi pha trong su\u1ed1t v\u00e0 kh\u00f4ng m\u00e0u ho\u1eb7c c\u00f3 m\u00e0u v\u00e0ng nh\u1ea1t<\/p>\n<p>C\u00f3 th\u1ec3 truy\u1ec1n t\u0129nh m\u1ea1ch trong 10 &#8211; 30 ph\u00fat. Pha mg b\u1ed9t esomeprazol v\u1edbi 5 ml natri clorid 0,9%, sau \u0111\u00f3 pha lo\u00e3ng t\u1edbi 100 ml \u0111\u1ec3 truy\u1ec1n). Dung d\u1ecbch \u0111\u00e3 pha kh\u00f4ng n\u00ean pha tr\u1ed9n ho\u1eb7c d\u00f9ng chung b\u1ed9 d\u00e2y truy\u1ec1n v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1c.<\/p>\n<p>L\u01b0u \u00fd:<\/p>\n<p>Dung d\u1ecbch \u0111\u00e3 pha n\u00ean \u0111\u01b0\u1ee3c ki\u1ec3m tra b\u1eb1ng m\u1eaft th\u01b0\u1eddng \u0111\u1ec3 ph\u00e1t hi\u1ec7n c\u00e1c ph\u00e2n t\u1eed l\u1ea1 v\u00e0 s\u1ef1 bi\u1ebfn m\u00e0u tr\u01b0\u1edbc khi d\u00f9ng. Ch\u1ec9 s\u1eed d\u1ee5ng dung d\u1ecbch trong su\u1ed1t . Ch\u1ec9 d\u00f9ng m\u1ed9t l\u1ea7n duy nh\u1ea5t. d\u00f9ng n\u1eeda th\u1ec3 t\u00edch pha n\u1ebfu ch\u1ec9 c\u1ea7n d\u00f9ng 20 mg esomeprazol, n\u00ean b\u1ecf ph\u1ea7n dung d\u1ecbch kh\u00f4ng s\u1eed d\u1ee5ng.<\/p>\n<p>Thu\u1ed1c n\u00ean \u0111\u01b0\u1ee3c d\u00f9ng ngay sau khi pha, ho\u1eb7c trong v\u00f2ng 12 gi\u1edd sau khi pha. B\u1ea3o qu\u1ea3n \u1edf nhi\u1ec7t \u0111\u1ed9 kh\u00f4ng qu\u00e1 30 \u0111\u1ed9 C<\/p>\n<p><strong><em>Li\u1ec1u d\u00f9ng:<\/em><\/strong><\/p>\n<p><em>\u0110i\u1ec1u tr\u1ecb lo\u00e9t d\u1ea1 d\u00e0y &#8211; t\u00e1 tr\u00e0ng c\u00f3 Helicobacter pylori<\/em>: Esomeprazol l\u00e0 m\u1ed9t th\u00e0nh ph\u1ea7n trong ch\u1ebf \u0111\u1ed9 \u0111i\u1ec1u tr\u1ecb c\u00f9ng v\u1edbi kh\u00e1ng sinh, Li\u1ec1u m\u1ed7i l\u1ea7n 20 mg, ng\u00e0y 2 l\u1ea7n trong 7 ng\u00e0y, ho\u1eb7c 40 mg\/l\u1ea7n\/ng\u00e0y trong 10 ng\u00e0y k\u1ebft h\u1ee3p v\u1edbi kh\u00e1ng sinh theo ph\u00e1c \u0111\u1ed3.<\/p>\n<p><em>\u0110i\u1ec1u tr\u1ecb b\u1ec7nh tr\u00e0o ng\u01b0\u1ee3c d\u1ea1 d\u00e0y &#8211; th\u1ef1c qu\u1ea3n n\u1eb7ng: <\/em>M\u1ed7i ng\u00e0y m\u1ed9t l\u1ea7n 40mg.<\/p>\n<p>B\u1ec7nh tr\u00e0o ng\u01b0\u1ee3c tri\u1ec7u ch\u1ee9ng kh\u00f4ng c\u00f3 vi\u00eam th\u1ef1c qu\u1ea3n: m\u1ed7i ng\u00e0y m\u1ed9t l\u1ea7n 20 mg.<\/p>\n<p>\u0110i\u1ec1u tr\u1ecb lo\u00e9t d\u1ea1 d\u00e0y do d\u00f9ng thu\u1ed1c ch\u1ed1ng vi\u00eam kh\u00f4ng steroid: 20 mg\/l\u1ea7n\/ng\u00e0y trong 4 &#8211; 8 tu\u1ea7n.<\/p>\n<p>\u0110i\u1ec1u tr\u1ecb h\u1ed9i ch\u1ee9ng Zollinger &#8211; Ellison: Tu\u1ef3 theo c\u00e1 th\u1ec3 v\u00e0 m\u1ee9c \u0111\u1ed9 t\u0103ng ti\u1ebft acid c\u1ee7a d\u1ecbch d\u1ea1 d\u00e0y, li\u1ec1u d\u00f9ng m\u1ed7i ng\u00e0y cao h\u01a1n trong c\u00e1c tr\u01b0\u1eddng h\u1ee3p kh\u00e1c, d\u00f9ng m\u1ed9t l\u1ea7n ho\u1eb7c chia l\u00e0m 2 l\u1ea7n trong ng\u00e0y. Khi tri\u1ec7u ch\u1ee9ng \u0111\u00e3 ki\u1ec3m so\u00e1t \u0111\u01b0\u1ee3c, c\u00f3 th\u1ec3 d\u00f9ng ph\u1eabu thu\u1eadt \u0111\u1ec3 c\u1eaft u. N\u1ebfu kh\u00f4ng c\u1eaft b\u1ecf u \u0111\u01b0\u1ee3c ho\u00e0n to\u00e0n, ph\u1ea3i d\u00f9ng thu\u1ed1c l\u00e2u d\u00e0i.<\/p>\n<p>Ng\u1eebng d\u00f9ng \u0111\u01b0\u1eddng ti\u00eam, truy\u1ec1n khi ng\u01b0\u1eddi b\u1ec7nh c\u00f3 th\u1ec3 u\u1ed1ng \u0111\u01b0\u1ee3c.<\/p>\n<p>Ng\u01b0\u1eddi suy gan n\u1eb7ng kh\u00f4ng d\u00f9ng qu\u00e1 20 mg m\u1ed9t ng\u00e0y.<\/p>\n<p>Kh\u00f4ng c\u1ea7n ph\u1ea3i gi\u1ea3m li\u1ec1u \u1edf ng\u01b0\u1eddi suy gan nh\u1eb9 v\u00e0 trung b\u00ecnh, ng\u01b0\u1eddi suy th\u1eadn ho\u1eb7c ng\u01b0\u1eddi cao tu\u1ed5i.<\/p>\n<p>Kh\u00f4ng d\u00f9ng thu\u1ed1c cho tr\u1ebb em.<\/p>\n<p><strong>4.3. Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh:<\/strong><\/p>\n<p>Qu\u00e1 m\u1eabn v\u1edbi c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf b\u01a1m proton ho\u1eb7c qu\u00e1 m\u1eabn v\u1edbi b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/p>\n<p><strong>4.4 Th\u1eadn tr\u1ecdng:<\/strong><\/p>\n<p>Tr\u01b0\u1edbc khi d\u00f9ng ESOVEX, ph\u1ea3i lo\u1ea1i tr\u1eeb kh\u1ea3 n\u0103ng ung th\u01b0 d\u1ea1 d\u00e0y v\u00ec thu\u1ed1c c\u00f3 th\u1ec3 che l\u1ea5p tri\u1ec7u ch\u1ee9ng, l\u00e0m ch\u1eadm ch\u1ea9n \u0111o\u00e1n ung th\u01b0. Th\u1eadn tr\u1ecdng khi d\u00f9ng \u1edf ng\u01b0\u1eddi b\u1ecb b\u1ec7nh gan, ng\u01b0\u1eddi mang thai ho\u1eb7c cho con b\u00fa.<\/p>\n<p>Ph\u1ea3i th\u1eadn tr\u1ecdng khi d\u00f9ng esomeprazol k\u00e9o d\u00e0i v\u00ec c\u00f3 th\u1ec3 g\u00e2y vi\u00eam teo d\u1ea1 d\u00e0y.<\/p>\n<p>Ph\u1ea3i th\u1eadn tr\u1ecdng khi d\u00f9ng cho tr\u1ebb em d\u01b0\u1edbi 18 tu\u1ed5i v\u00ec \u0111\u1ed9 an to\u00e0n v\u00e0 hi\u1ec7u qu\u1ea3 ch\u01b0a \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh. Thu\u1ed1c kh\u00f4ng \u0111\u01b0\u1ee3c khuy\u1ebfn c\u00e1o d\u00f9ng cho tr\u1ebb em.<\/p>\n<p><strong>T\u00e1c \u0111\u1ed9ng c\u1ee7a thu\u1ed1c tr\u00ean ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/strong><\/p>\n<p>Th\u1eadn tr\u1ecdng v\u00ec thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y \u0111au \u0111\u1ea7u, ch\u00f3ng m\u1eb7t<\/p>\n<p><script src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-5528370293090692\" async=\"\" crossorigin=\"anonymous\"><\/script><ins class=\"adsbygoogle\" style=\"display: block; text-align: center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-5528370293090692\" data-ad-slot=\"8909623906\"><\/ins><script> (adsbygoogle = window.adsbygoogle || []).push({}); <\/script><\/p>\n<p><strong>4.5 S\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa:<\/strong><\/p>\n<p><em>X\u1ebfp h\u1ea1ng c\u1ea3nh b\u00e1o<\/em><\/p>\n<p>AU TGA pregnancy category: B3<\/p>\n<p>US FDA pregnancy category: NA<\/p>\n<p><em>Th\u1eddi k\u1ef3 mang thai:<\/em><\/p>\n<p>Ch\u01b0a c\u00f3 nghi\u00ean c\u1ee9u \u0111\u1ea7y \u0111\u1ee7 khi d\u00f9ng esomeprazol \u1edf ng\u01b0\u1eddi mang thai. Tr\u00ean \u0111\u1ed9ng v\u1eadt, chu\u1ed9t c\u1ed1ng tr\u1eafng u\u1ed1ng esomeprazol li\u1ec1u 280 mg\/kg\/ng\u00e0y (g\u1ea5p 57 l\u1ea7n li\u1ec1u d\u00f9ng tr\u00ean ng\u01b0\u1eddi t\u00ednh theo di\u1ec7n t\u00edch b\u1ec1 m\u1eb7t c\u01a1 th\u1ec3) v\u00e0 th\u1ecf u\u1ed1ng li\u1ec1u 86 mg\/kg\/ng\u00e0y (g\u1ea5p 35 l\u1ea7n li\u1ec1u d\u00f9ng tr\u00ean ng\u01b0\u1eddi t\u00ednh theo di\u1ec7n t\u00edch b\u1ec1 m\u1eb7t c\u01a1 th\u1ec3) \u0111\u00e3 kh\u00f4ng th\u1ea5y b\u1eb1ng ch\u1ee9ng v\u1ec1 suy gi\u1ea3m kh\u1ea3 n\u0103ng sinh s\u1ea3n ho\u1eb7c \u0111\u1ed9c \u0111\u1ed1i v\u1edbi thai do esomeprazol. Tuy nhi\u00ean, ch\u1ec9 s\u1eed d\u1ee5ng esomeprazol khi th\u1eadt c\u1ea7n thi\u1ebft trong th\u1eddi k\u1ef3 mang thai.<\/p>\n<p><em>Th\u1eddi k\u1ef3 cho con b\u00fa:<\/em><\/p>\n<p>Ch\u01b0a bi\u1ebft esomeprazol c\u00f3 b\u00e0i ti\u1ebft v\u00e0o s\u1eefa ng\u01b0\u1eddi hay kh\u00f4ng. Tuy nhi\u00ean \u0111\u00e3 \u0111o \u0111\u01b0\u1ee3c n\u1ed3ng \u0111\u1ed9 c\u1ee7a omeprazol trong s\u1eefa c\u1ee7a ph\u1ee5 n\u1eef sau khi u\u1ed1ng 20 mg omeprazol. Esomeprazol c\u00f3 kh\u1ea3 n\u0103ng g\u00e2y ra c\u00e1c t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n nghi\u00eam tr\u1ecdng \u1edf tr\u1ebb b\u00fa m\u1eb9, v\u00ec v\u1eady ph\u1ea3i quy\u1ebft \u0111\u1ecbnh ng\u1eebng cho con b\u00fa ho\u1eb7c ng\u1eebng thu\u1ed1c, t\u00f9y theo t\u1ea7m quan tr\u1ecdng c\u1ee7a vi\u1ec7c d\u00f9ng thu\u1ed1c \u0111\u1ed1i v\u1edbi ng\u01b0\u1eddi m\u1eb9.<\/p>\n<p><strong>4.6 T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n (ADR):<\/strong><\/p>\n<p>Nh\u00ecn chung, esomeprazol dung n\u1ea1p t\u1ed1t c\u1ea3 khi s\u1eed d\u1ee5ng trong th\u1eddi gian ng\u1eafn ho\u1eb7c th\u1eddi gian d\u00e0i.<\/p>\n<p><em>Th\u01b0\u1eddng g\u1eb7p, ADR &gt; 1\/100<\/em><\/p>\n<p>To\u00e0n th\u00e2n: \u0110au \u0111\u1ea7u, ch\u00f3ng m\u1eb7t, ban ngo\u00e0i da.<\/p>\n<p>Ti\u00eau h\u00f3a: Bu\u1ed3n n\u00f4n, n\u00f4n, \u0111au b\u1ee5ng, ti\u00eau ch\u1ea3y, t\u00e1o b\u00f3n, \u0111\u1ea7y h\u01a1i, kh\u00f4 mi\u1ec7ng.<\/p>\n<p><em>\u00cdt g\u1eb7p, 1\/1000 &lt; ADR &lt; 1\/100.<\/em><\/p>\n<p>To\u00e0n th\u00e2n: M\u1ec7t m\u1ecfi, m\u1ea5t ng\u1ee7, bu\u1ed3n ng\u1ee7, ph\u00e1t ban, ng\u1ee9a.<\/p>\n<p>R\u1ed1i lo\u1ea1n th\u1ecb gi\u00e1c.<\/p>\n<p><em>Hi\u1ebfm g\u1eb7p, ADR &lt; 1\/1000<\/em><\/p>\n<p>To\u00e0n th\u00e2n: S\u1ed1t, \u0111\u1ed5 m\u1ed3 h\u00f4i, ph\u00f9 ngo\u1ea1i bi\u00ean, m\u1eabn c\u1ea3m v\u1edbi \u00e1nh s\u00e1ng, ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn (bao g\u1ed3m m\u00e0y \u0111ay, ph\u00f9 m\u1ea1ch, co th\u1eaft ph\u1ebf qu\u1ea3n, s\u1ed1c ph\u1ea3n v\u1ec7).<\/p>\n<p>Th\u1ea7n kinh trung \u01b0\u01a1ng: K\u00edch \u0111\u1ed9ng, tr\u1ea7m c\u1ea3m, l\u00fa l\u1eabn c\u00f3 h\u1ed3i ph\u1ee5c, \u1ea3o gi\u00e1c \u1edf ng\u01b0\u1eddi b\u1ec7nh n\u1eb7ng.<\/p>\n<p>Huy\u1ebft h\u1ecdc: Ch\u1ee9ng m\u1ea5t b\u1ea1ch c\u1ea7u h\u1ea1t, gi\u1ea3m b\u1ea1ch c\u1ea7u, gi\u1ea3m ti\u1ec3u c\u1ea7u.<\/p>\n<p>Gan: T\u0103ng enzym gan, vi\u00eam gan, v\u00e0ng da, suy ch\u1ee9c n\u0103ng gan.<\/p>\n<p>Ti\u00eau h\u00f3a: R\u1ed1i lo\u1ea1n v\u1ecb gi\u00e1c.<\/p>\n<p>C\u01a1 x\u01b0\u01a1ng: \u0110au kh\u1edbp, \u0111au c\u01a1.<\/p>\n<p>Ti\u1ebft ni\u1ec7u: Vi\u00eam th\u1eadn k\u1ebd.<\/p>\n<p>Da: Ban b\u1ecdng n\u01b0\u1edbc, h\u1ed9i ch\u1ee9ng Stevens &#8211; Johnson, ho\u1ea1i t\u1eed bi\u1ec3u b\u00ec nhi\u1ec5m \u0111\u1ed9c, vi\u00eam da.<\/p>\n<p>Do l\u00e0m gi\u1ea3m \u0111\u1ed9 acid c\u1ee7a d\u1ea1 d\u00e0y, c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf b\u01a1m proton c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 nhi\u1ec5m khu\u1ea9n \u1edf \u0111\u01b0\u1eddng ti\u00eau h\u00f3a.<\/p>\n<p><em>Th\u00f4ng b\u00e1o cho B\u00e1c s\u0129 nh\u1eefng t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n g\u1eb7p ph\u1ea3i khi s\u1eed d\u1ee5ng thu\u1ed1c.<\/em><\/p>\n<p><strong>4.7 H\u01b0\u1edbng d\u1eabn c\u00e1ch x\u1eed tr\u00ed ADR:<\/strong><\/p>\n<p>Ng\u1eebng s\u1eed d\u1ee5ng thu\u1ed1c. V\u1edbi c\u00e1c ph\u1ea3n \u1ee9ng b\u1ea5t l\u1ee3i nh\u1eb9, th\u01b0\u1eddng ch\u1ec9 c\u1ea7n ng\u1eebng thu\u1ed1c. Tr\u01b0\u1eddng h\u1ee3p m\u1eabn c\u1ea3m n\u1eb7ng ho\u1eb7c ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng, c\u1ea7n ti\u1ebfn h\u00e0nh \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3 (gi\u1eef tho\u00e1ng kh\u00ed v\u00e0 d\u00f9ng epinephrin, th\u1edf oxygen, d\u00f9ng kh\u00e1ng histamin, corticoid&#8230;).<\/p>\n<p><strong>4.8 T\u01b0\u01a1ng t\u00e1c v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1c:<\/strong><\/p>\n<p>Do \u1ee9c ch\u1ebf b\u00e0i ti\u1ebft acid, esomeprazol l\u00e0m t\u0103ng pH d\u1ea1 d\u00e0y, \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn sinh kh\u1ea3 d\u1ee5ng c\u1ee7a c\u00e1c thu\u1ed1c h\u1ea5p thu ph\u1ee5 thu\u1ed9c pH: ketoconazol, mu\u1ed1i s\u1eaft, digoxin.<\/p>\n<p>D\u00f9ng \u0111\u1ed3ng th\u1eddi esomeprazol, clarithromycin v\u00e0 amoxicilin l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 esomeprazol v\u00e0 14-hydroxyclarithromycin trong m\u00e1u.<\/p>\n<p>Esomeprazol t\u01b0\u01a1ng t\u00e1c d\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc v\u1edbi c\u00e1c thu\u1ed1c chuy\u1ec3n h\u00f3a b\u1edfi h\u1ec7 enzym cytochrom P450, isoenzym CYP2C19 \u1edf gan. D\u00f9ng \u0111\u1ed3ng th\u1eddi 30 mg esomeprazol v\u00e0 diazepam l\u00e0m gi\u1ea3m 45% \u0111\u1ed9 thanh th\u1ea3i c\u1ee7a diazepam.<\/p>\n<p><strong>4.9 Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed:<\/strong><\/p>\n<p>Ch\u01b0a c\u00f3 b\u00e1o c\u00e1o v\u1ec1 qu\u00e1 li\u1ec1u esomeprazol \u1edf ng\u01b0\u1eddi.<\/p>\n<p>Kh\u00f4ng c\u00f3 thu\u1ed1c gi\u1ea3i \u0111\u1ed9c \u0111\u1eb7c hi\u1ec7u cho esomeprazol. Ch\u1ee7 y\u1ebfu \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng v\u00e0 h\u1ed7 tr\u1ee3. Th\u1ea9m t\u00e1ch m\u00e1u kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng t\u0103ng th\u1ea3i tr\u1eeb thu\u1ed1c v\u00ec thu\u1ed1c g\u1eafn nhi\u1ec1u v\u00e0o protein.<\/p>\n<p><script src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-5528370293090692\" async=\"\" crossorigin=\"anonymous\"><\/script><ins class=\"adsbygoogle\" style=\"display: block; text-align: center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-5528370293090692\" data-ad-slot=\"8909623906\"><\/ins><script> (adsbygoogle = window.adsbygoogle || []).push({}); <\/script><\/p>\n<p><strong>5. C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c :<\/strong><\/p>\n<p><strong>5.1. D\u01b0\u1ee3c l\u1ef1c h\u1ecdc:<\/strong><\/p>\n<p>Esomeprazol l\u00e0 d\u1ea1ng \u0111\u1ed3ng ph\u00e2n S c\u1ee7a omeprazol, \u0111\u01b0\u1ee3c d\u00f9ng t\u01b0\u01a1ng t\u1ef1 nh\u01b0 omeprazol trong \u0111i\u1ec1u tr\u1ecb lo\u00e9t d\u1ea1 d\u00e0y &#8211; t\u00e1 tr\u00e0ng v\u00e0 b\u1ec7nh tr\u00e0o ng\u01b0\u1ee3c d\u1ea1 d\u00e0y &#8211; th\u1ef1c qu\u1ea3n.<\/p>\n<p>Esomeprazol g\u1eafn v\u1edbi H+\/K+ &#8211; ATPase (c\u00f2n g\u1ecdi l\u00e0 b\u01a1m proton) \u1edf t\u1ebf b\u00e0o th\u00e0nh c\u1ee7a d\u1ea1 d\u00e0y, \u1ee9c ch\u1ebf \u0111\u1eb7c hi\u1ec7u h\u1ec7 th\u1ed1ng enzym n\u00e0y, ng\u0103n c\u1ea3n b\u01b0\u1edbc cu\u1ed1i c\u00f9ng c\u1ee7a s\u1ef1 b\u00e0i ti\u1ebft acid v\u00e0o l\u00f2ng d\u1ea1 d\u00e0y. V\u00ec v\u1eady esomeprazol c\u00f3 t\u00e1c d\u1ee5ng \u1ee9c ch\u1ebf d\u1ea1 d\u00e0y ti\u1ebft acid c\u01a1 b\u1ea3n v\u00e0 c\u1ea3 khi b\u1ecb k\u00edch th\u00edch do b\u1ea5t k\u1ef3 t\u00e1c nh\u00e2n n\u00e0o.<\/p>\n<p><strong><em>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng: <\/em><\/strong><\/p>\n<p>Esomeprazol l\u00e0 thu\u1ed1c \u1ee9c ch\u1ebf b\u01a1m proton l\u00e0m gi\u1ea3m ti\u1ebft acid d\u1ea1 d\u00e0y b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf chuy\u00ean bi\u1ec7t enzym H<sup>+<\/sup>\/K<sup>+<\/sup>\u00a0&#8211; ATPase t\u1ea1i t\u1ebf b\u00e0o th\u00e0nh c\u1ee7a d\u1ea1 d\u00e0y.<\/p>\n<p>Esomeprazol l\u00e0 \u0111\u1ed3ng ph\u00e2n S c\u1ee7a omeprazol, \u0111\u01b0\u1ee3c proton h\u00f3a v\u00e0 bi\u1ebfn \u0111\u1ed5i trong khoang c\u00f3 t\u00ednh acid c\u1ee7a t\u1ebf b\u00e0o th\u00e0nh t\u1ea1o th\u00e0nh ch\u1ea5t \u1ee9c ch\u1ebf c\u00f3 ho\u1ea1t t\u00ednh, d\u1ea1ng sulphenamid kh\u00f4ng \u0111\u1ed1i quang. Do t\u00e1c \u0111\u1ed9ng chuy\u00ean bi\u1ec7t tr\u00ean b\u01a1m proton, esomeprazol ng\u0103n ch\u1eb7n b\u01b0\u1edbc cu\u1ed1i c\u00f9ng trong qu\u00e1 tr\u00ecnh s\u1ea3n xu\u1ea5t acid, qua \u0111\u00f3 l\u00e0m gi\u1ea3m \u0111\u1ed9 acid d\u1ea1 d\u00e0y. T\u00e1c d\u1ee5ng n\u00e0y ph\u1ee5 thu\u1ed9c v\u00e0o li\u1ec1u d\u00f9ng m\u1ed7i ng\u00e0y t\u1eeb 20 &#8211; 40mg v\u00e0 \u0111\u01b0a \u0111\u1ebfn \u1ee9c ch\u1ebf ti\u1ebft acid d\u1ea1 d\u00e0y.<\/p>\n<p><a href=\"https:\/\/www.youtube.com\/watch?v=wgt47Xu6X-4\"><strong>[XEM T\u1ea0I \u0110\u00c2Y]<\/strong><\/a><\/p>\n<p><strong>5.2. D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc:<\/strong><\/p>\n<p>Kho\u1ea3ng 97% esomeprazol g\u1eafn v\u00e0o protein huy\u1ebft t\u01b0\u01a1ng. Th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 khi n\u1ed3ng \u0111\u1ed9 thu\u1ed1c \u1ed5n \u0111\u1ecbnh \u1edf ng\u01b0\u1eddi t\u00ecnh nguy\u1ec7n kh\u1ecfe m\u1ea1nh l\u00e0 16 l\u00edt.<\/p>\n<p>Thu\u1ed1c chuy\u1ec3n h\u00f3a ch\u1ee7 y\u1ebfu \u1edf gan nh\u1edd isoenzym CYP2C19, h\u1ec7 enzym cytochrom P450, th\u00e0nh c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a hydroxy v\u00e0 desmethyl kh\u00f4ng c\u00f2n ho\u1ea1t t\u00ednh. Ph\u1ea7n c\u00f2n l\u1ea1i \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a qua isoenzym CYP3A4 th\u00e0nh esomeprazol sulfon. Khi d\u00f9ng nh\u1eafc l\u1ea1i, chuy\u1ec3n h\u00f3a b\u01b0\u1edbc \u0111\u1ea7u qua gan v\u00e0 \u0111\u1ed9 thanh th\u1ea3i c\u1ee7a thu\u1ed1c gi\u1ea3m, c\u00f3 th\u1ec3 do isoenzym CYP2C19 b\u1ecb \u1ee9c ch\u1ebf. Tuy nhi\u00ean, kh\u00f4ng c\u00f3 hi\u1ec7n t\u01b0\u1ee3ng t\u00edch l\u0169y thu\u1ed1c khi d\u00f9ng m\u1ed7i ng\u00e0y 1 l\u1ea7n. \u1ede m\u1ed9t s\u1ed1 ng\u01b0\u1eddi v\u00ec thi\u1ebfu CYP2C19 do di truy\u1ec1n (15 &#8211; 20% ng\u01b0\u1eddi ch\u00e2u \u00c1), n\u00ean l\u00e0m ch\u1eadm chuy\u1ec3n h\u00f3a esomeprazol, d\u1eabn \u0111\u1ebfn gi\u00e1 tr\u1ecb AUC t\u0103ng cao kho\u1ea3ng 2 l\u1ea7n so v\u1edbi ng\u01b0\u1eddi c\u00f3 \u0111\u1ee7 enzym. N\u1eeda \u0111\u1eddi th\u1ea3i tr\u1eeb trong huy\u1ebft t\u01b0\u01a1ng 1 &#8211; 1,5 gi\u1edd. Kho\u1ea3ng 80% li\u1ec1u u\u1ed1ng \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb d\u01b0\u1edbi d\u1ea1ng c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a kh\u00f4ng c\u00f3 ho\u1ea1t t\u00ednh trong n\u01b0\u1edbc ti\u1ec3u, ph\u1ea7n c\u00f2n l\u1ea1i \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb trong ph\u00e2n. D\u01b0\u1edbi 1% ch\u1ea5t m\u1eb9 \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb trong n\u01b0\u1edbc ti\u1ec3u. \u1ede ng\u01b0\u1eddi suy gan n\u1eb7ng, li\u1ec1u d\u00f9ng kh\u00f4ng qu\u00e1 20 mg m\u1ed9t ng\u00e0y.<\/p>\n<p>D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc c\u1ee7a esomeprazol \u1edf ng\u01b0\u1eddi d\u01b0\u1edbi 18 tu\u1ed5i ch\u01b0a \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u.<\/p>\n<p><strong>5.3 Gi\u1ea3i th\u00edch: <\/strong><\/p>\n<p>Ch\u01b0a c\u00f3 th\u00f4ng tin. \u0110ang c\u1eadp nh\u1eadt.<\/p>\n<p><strong>5.4 Thay th\u1ebf thu\u1ed1c : <\/strong><\/p>\n<p>Ch\u01b0a c\u00f3 th\u00f4ng tin. \u0110ang c\u1eadp nh\u1eadt.<\/p>\n<p><strong><em>*L\u01b0u \u00fd:<\/em><\/strong><\/p>\n<p><strong><em>C\u00e1c th\u00f4ng tin v\u1ec1 thu\u1ed1c tr\u00ean Pharmog.com ch\u1ec9 mang t\u00ednh ch\u1ea5t tham kh\u1ea3o &#8211; Khi d\u00f9ng thu\u1ed1c c\u1ea7n tuy\u1ec7t \u0111\u1ed1i tu\u00e2n theo theo h\u01b0\u1edbng d\u1eabn c\u1ee7a B\u00e1c s\u0129 <\/em><\/strong><\/p>\n<p><strong><em>Ch\u00fang t\u00f4i kh\u00f4ng c<\/em><\/strong><strong><em>h\u1ecbu tr\u00e1ch nhi\u1ec7m v\u1ec1 b\u1ea5t c\u1ee9 h\u1eadu qu\u1ea3 n\u00e0o x\u1ea3y ra do t\u1ef1 \u00fd d\u00f9ng thu\u1ed1c d\u1ef1a theo c\u00e1c th\u00f4ng tin tr\u00ean Pharmog.com<\/em><\/strong><\/p>\n<p><script src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-5528370293090692\" async=\"\" crossorigin=\"anonymous\"><\/script><ins class=\"adsbygoogle\" style=\"display: block; text-align: center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-5528370293090692\" data-ad-slot=\"8909623906\"><\/ins><script> (adsbygoogle = window.adsbygoogle || []).push({}); <\/script><\/p>\n<p><strong>6. Ph\u1ea7n th\u00f4ng tin k\u00e8m theo c\u1ee7a thu\u1ed1c:<\/strong><\/p>\n<p><strong>6.1. Danh m\u1ee5c t\u00e1 d\u01b0\u1ee3c:<\/strong><\/p>\n<p>&#8230;<\/p>\n<p><strong>6.2. T\u01b0\u01a1ng k\u1ef5 :<\/strong><\/p>\n<p>Dung d\u1ecbch \u0111\u00e3 pha kh\u00f4ng n\u00ean pha tr\u1ed9n ho\u1eb7c d\u00f9ng chung b\u1ed9 d\u00e2y truy\u1ec1n v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1c.<\/p>\n<p><strong>6.3. B\u1ea3o qu\u1ea3n: <\/strong><\/p>\n<p>N\u01a1i kh\u00f4, kh\u00f4ng qu\u00e1 30\u00b0C, tr\u00e1nh \u00e1nh s\u00e1ng.<\/p>\n<p>Thu\u1ed1c n\u00ean \u0111\u01b0\u1ee3c d\u00f9ng ngay sau khi pha, ho\u1eb7c trong v\u00f2ng 12 gi\u1edd sau khi pha.<\/p>\n<p><strong>6.4. Th\u00f4ng tin kh\u00e1c :<\/strong><\/p>\n<p>Kh\u00f4ng c\u00f3.<\/p>\n<p><strong>6.5 T\u00e0i li\u1ec7u tham kh\u1ea3o:<\/strong><\/p>\n<p>D\u01b0\u1ee3c Th\u01b0 Qu\u1ed1c Gia Vi\u1ec7t Nam<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>1. T\u00ean ho\u1ea1t ch\u1ea5t v\u00e0 bi\u1ec7t d\u01b0\u1ee3c: Ho\u1ea1t ch\u1ea5t : Esomeprazole Ph\u00e2n lo\u1ea1i: Thu\u00f4\u0301c \u01b0\u0301c ch\u00ea\u0301 b\u01a1m Proton. Nh\u00f3m ph\u00e1p l\u00fd: Thu\u1ed1c k\u00ea \u0111\u01a1n ETC \u2013 (Ethical drugs, prescription drugs, Prescription only medicine) M\u00e3 ATC (Anatomical Therapeutic Chemical): A02BC05. Bi\u1ec7t d\u01b0\u1ee3c g\u1ed1c: Nexium injection, Nexium Mups , Nexium Sachet Bi\u1ec7t d\u01b0\u1ee3c: Esovex H\u00e3ng s\u1ea3n xu\u1ea5t [&hellip;]<\/p>\n","protected":false},"author":8612,"featured_media":22808,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[419],"tags":[785],"class_list":["post-22807","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-biet-duoc","tag-esomeprazole"],"_links":{"self":[{"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/posts\/22807","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/users\/8612"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/comments?post=22807"}],"version-history":[{"count":3,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/posts\/22807\/revisions"}],"predecessor-version":[{"id":48473,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/posts\/22807\/revisions\/48473"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/media\/22808"}],"wp:attachment":[{"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/media?parent=22807"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/categories?post=22807"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/tags?post=22807"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}