{"id":1788,"date":"2018-11-15T11:50:05","date_gmt":"2018-11-15T04:50:05","guid":{"rendered":"https:\/\/pharmog.com\/wp\/?p=1788"},"modified":"2025-01-08T22:06:48","modified_gmt":"2025-01-08T15:06:48","slug":"fluvoxamine","status":"publish","type":"post","link":"https:\/\/pharmog.com\/wp\/fluvoxamine\/","title":{"rendered":"Fluvoxamine"},"content":{"rendered":"<p><strong>1. T\u00ean ho\u1ea1t ch\u1ea5t v\u00e0 bi\u1ec7t d\u01b0\u1ee3c: <\/strong><\/p>\n<p><strong><em>Ho\u1ea1t ch\u1ea5t :<\/em> Fluvoxamine maleate<\/strong><\/p>\n<p><strong><em>Ph\u00e2n lo\u1ea1i: <\/em><\/strong><em>Thu\u00f4\u0301c \u1ee9c ch\u1ebf t\u00e1i h\u1ea5p thu serotonin ch\u1ecdn l\u1ecdc (SSRIs)<\/em><\/p>\n<p><strong><em>Nh\u00f3m<\/em><\/strong> <strong><em>ph\u00e1p l\u00fd: <\/em><\/strong><em>Thu\u1ed1c k\u00ea \u0111\u01a1n ETC \u2013 (Ethical drugs, prescription drugs, Prescription only medicine)<\/em><\/p>\n<p><strong><em>M\u00e3 ATC<\/em><\/strong> (Anatomical Therapeutic Chemical): N06AB08.<\/p>\n<p><strong><em>Brand name:<\/em><\/strong> <a href=\"https:\/\/pharmog.com\/wp\/fluvoxamine-luvox\/\">Luvox<\/a><\/p>\n<p><strong><em>Generic <\/em><\/strong>: Fluvoxamine ,\u00a0Fanzini<\/p>\n<p><script src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-5528370293090692\" async=\"\" crossorigin=\"anonymous\"><\/script><ins class=\"adsbygoogle\" style=\"display: block; text-align: center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-5528370293090692\" data-ad-slot=\"8909623906\"><\/ins><script> (adsbygoogle = window.adsbygoogle || []).push({}); <\/script><\/p>\n<p><strong>2. D\u1ea1ng b\u00e0o ch\u1ebf &#8211; H\u00e0m l\u01b0\u1ee3ng: <\/strong><\/p>\n<p><strong><em>D\u1ea1ng thu\u1ed1c v\u00e0 h\u00e0m l\u01b0\u1ee3ng<\/em><\/strong><\/p>\n<p>Vi\u00ean n\u00e9n bao phim 50 mg, 100 mg.<\/p>\n<p>Vi\u00ean nang gi\u1ea3i ph\u00f3ng ch\u1eadm 150mg<\/p>\n<p><strong><em>Thu\u1ed1c tham kh\u1ea3o:<\/em><\/strong><\/p>\n<table>\n<tbody>\n<tr>\n<td colspan=\"2\"><strong><em>FANZINI<\/em><\/strong><\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\"><em>M\u1ed7i vi\u00ean nang c\u00f3 ch\u1ee9a:<\/em><\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td>Fluvoxamine maleate<\/td>\n<td>&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.<\/td>\n<td>100 mg<\/td>\n<\/tr>\n<tr>\n<td>T\u00e1 d\u01b0\u1ee3c<\/td>\n<td>&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.<\/td>\n<td>v\u1eeba \u0111\u1ee7 (Xem m\u1ee5c 6.1)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-23536\" src=\"https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2018\/11\/Fanzini.png\" alt=\"\" width=\"558\" height=\"229\" srcset=\"https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2018\/11\/Fanzini.png 558w, https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2018\/11\/Fanzini-300x123.png 300w, https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2018\/11\/Fanzini-280x115.png 280w\" sizes=\"auto, (max-width: 558px) 100vw, 558px\" \/><\/p>\n<p><strong>3. Video by Pharmog:<\/strong><\/p>\n<p><strong>[VIDEO D\u01af\u1ee2C L\u00dd]<\/strong><\/p>\n<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<\/p>\n<p>\u25ba K\u1ecbch B\u1ea3n: PharmogTeam<\/p>\n<p>\u25ba Youtube: https:\/\/www.youtube.com\/c\/pharmog<\/p>\n<p>\u25ba Facebook: https:\/\/www.facebook.com\/pharmog\/<\/p>\n<p>\u25ba Group : H\u1ed9i nh\u1eefng ng\u01b0\u1eddi m\u00ea d\u01b0\u1ee3c l\u00fd<\/p>\n<p>\u25ba Instagram : https:\/\/www.instagram.com\/pharmogvn\/<\/p>\n<p>\u25ba Website: pharmog.com<\/p>\n<p><strong>4. \u1ee8ng d\u1ee5ng l\u00e2m s\u00e0ng: <\/strong><\/p>\n<p><strong>4.1. Ch\u1ec9 \u0111\u1ecbnh:<\/strong><\/p>\n<p>\u0110i\u1ec1u tr\u1ecb b\u1ec7nh tr\u1ea7m c\u1ea3m v\u00e0 c\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a r\u1ed1i lo\u1ea1n tr\u1ea7m c\u1ea3m.<\/p>\n<p>\u0110i\u1ec1u tr\u1ecb c\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a r\u1ed1i lo\u1ea1n xung l\u1ef1c c\u01b0\u1ee1ng b\u1ee9c \u00e1m \u1ea3nh (OCD).<\/p>\n<p><strong>4.2. Li\u1ec1u d\u00f9ng &#8211; C\u00e1ch d\u00f9ng:<\/strong><\/p>\n<p><strong><em>C\u00e1ch d\u00f9ng<\/em><\/strong> :<\/p>\n<p>Nu\u1ed1t vi\u00ean c\u00f9ng v\u1edbi n\u01b0\u1edbc v\u00e0 kh\u00f4ng \u0111\u01b0\u1ee3c nhai.<\/p>\n<p><strong><em>Li\u1ec1u d\u00f9ng:<\/em><\/strong><\/p>\n<p><em>Tr\u1ea7m c\u1ea3m:<\/em><\/p>\n<p>Li\u1ec1u kh\u1edfi \u0111\u1ea7u khuy\u1ebfn c\u00e1o l\u00e0 50 mg ho\u1eb7c 100 mg, d\u00f9ng li\u1ec1u \u0111\u01a1n v\u00e0o bu\u1ed5i t\u1ed1i. T\u0103ng li\u1ec1u d\u1ea7n d\u1ea7n cho \u0111\u1ebfn khi \u0111\u1ea1t \u0111\u01b0\u1ee3c li\u1ec1u c\u00f3 hi\u1ec7u l\u1ef1c. Li\u1ec1u c\u00f3 hi\u1ec7u l\u1ef1c th\u00f4ng th\u01b0\u1eddng l\u00e0 100 mg\/ng\u00e0y v\u00e0 n\u00ean \u0111\u01b0\u1ee3c \u0111i\u1ec1u ch\u1ec9nh theo \u0111\u00e1p \u1ee9ng c\u1ee7a t\u1eebng b\u1ec7nh nh\u00e2n. Li\u1ec1u l\u00ean \u0111\u1ebfn 300 mg\/ng\u00e0y \u0111\u00e3 \u0111\u01b0\u1ee3c d\u00f9ng. Li\u1ec1u tr\u00ean 150 mg n\u00ean \u0111\u01b0\u1ee3c chia th\u00e0nh nhi\u1ec1u l\u1ea7n u\u1ed1ng.<\/p>\n<p>Theo b\u00e1o c\u00e1o c\u1ee7a T\u1ed5 ch\u1ee9c Y t\u1ebf th\u1ebf gi\u1edbi, thu\u1ed1c ch\u1ed1ng tr\u1ea7m c\u1ea3m ph\u1ea3i \u0111\u01b0\u1ee3c d\u00f9ng ti\u1ebfp t\u1ee5c trong \u00edt nh\u1ea5t l\u00e0 6 th\u00e1ng sau khi kh\u1ecfi giai \u0111o\u1ea1n tr\u1ea7m c\u1ea3m.<\/p>\n<p>Fluvoxamine \u1edf li\u1ec1u \u0111\u01a1n c\u1ed1 \u0111\u1ecbnh h\u00e0ng ng\u00e0y 100 mg l\u00e0 li\u1ec1u khuy\u1ebfn c\u00e1o \u0111\u1ec3 d\u1ef1 ph\u00f2ng tr\u1ea7m c\u1ea3m t\u00e1i ph\u00e1t.<\/p>\n<p><em>R\u1ed1i lo\u1ea1n xung l\u1ef1c c\u01b0\u1ee1ng b\u1ee9c \u00e1m \u1ea3nh:<\/em><\/p>\n<p>Li\u1ec1u kh\u1edfi \u0111\u1ea7u khuy\u1ebfn c\u00e1o l\u00e0 50 mg\/ng\u00e0y d\u00f9ng trong 3-4 ng\u00e0y. Li\u1ec1u c\u00f3 hi\u1ec7u l\u1ef1c th\u01b0\u1eddng t\u1eeb 100 mg \u0111\u1ebfn 300 mg\/ng\u00e0y. T\u0103ng li\u1ec1u d\u1ea7n d\u1ea7n cho \u0111\u1ebfn khi \u0111\u1ea1t \u0111\u01b0\u1ee3c li\u1ec1u c\u00f3 hi\u1ec7u l\u1ef1c, t\u1ed1i \u0111a l\u00e0 300 mg\/ng\u00e0y \u0111\u1ed1i v\u1edbi ng\u01b0\u1eddi l\u1edbn v\u00e0 200 mg\/ng\u00e0y \u0111\u1ed1i v\u1edbi thi\u1ebfu ni\u00ean v\u00e0 tr\u1ebb em t\u1eeb 8 tu\u1ed5i tr\u1edf l\u00ean. Li\u1ec1u l\u00ean \u0111\u1ebfn 150 mg\/ng\u00e0y c\u00f3 th\u1ec3 d\u00f9ng nh\u01b0 l\u00e0 li\u1ec1u \u0111\u01a1n, t\u1ed1t nh\u1ea5t l\u00e0 u\u1ed1ng v\u00e0o bu\u1ed5i t\u1ed1i. T\u1ed5ng li\u1ec1u h\u00e0ng ng\u00e0y tr\u00ean 150 mg n\u00ean \u0111\u01b0\u1ee3c chia th\u00e0nh 2 ho\u1eb7c 3 l\u1ea7n u\u1ed1ng.<\/p>\n<p>N\u1ebfu \u0111\u00e3 \u0111\u1ea1t \u0111\u01b0\u1ee3c \u0111\u00e1p \u1ee9ng t\u1ed1t th\u00ec c\u00f3 th\u1ec3 ti\u1ebfp t\u1ee5c \u0111i\u1ec1u tr\u1ecb v\u1edbi li\u1ec1u d\u00f9ng \u0111\u01b0\u1ee3c \u0111i\u1ec1u ch\u1ec9nh theo t\u1eebng b\u1ec7nh nh\u00e2n. N\u1ebfu kh\u00f4ng c\u00f3 c\u1ea3i thi\u1ec7n g\u00ec trong v\u00f2ng 10 tu\u1ea7n, vi\u1ec7c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Fluvoxamine n\u00ean \u0111\u01b0\u1ee3c xem x\u00e9t l\u1ea1i. Trong khi ch\u01b0a c\u00f3 c\u00e1c nghi\u00ean c\u1ee9u c\u00f3 h\u1ec7 th\u1ed1ng \u0111\u1ec3 tr\u1ea3 l\u1eddi c\u00e2u h\u1ecfi n\u00ean ti\u1ebfp t\u1ee5c \u0111i\u1ec1u tr\u1ecb Fluvoxamine trong bao l\u00e2u, r\u1ed1i lo\u1ea1n xung l\u1ef1c c\u01b0\u1ee1ng b\u1ee9c \u00e1m \u1ea3nh (OCD) l\u00e0 m\u1ed9t t\u00ecnh tr\u1ea1ng m\u00e3n t\u00ednh v\u00e0 n\u00ean c\u00e2n nh\u1eafc ti\u1ebfp t\u1ee5c \u0111i\u1ec1u tr\u1ecb tr\u00ean 10 tu\u1ea7n cho nh\u1eefng b\u1ec7nh nh\u00e2n \u0111\u00e1p \u1ee9ng. Vi\u1ec7c \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u n\u00ean th\u1eadn tr\u1ecdng t\u00f9y theo t\u1eebng b\u1ec7nh nh\u00e2n \u0111\u1ec3 duy tr\u00ec cho b\u1ec7nh nh\u00e2n d\u00f9ng li\u1ec1u th\u1ea5p nh\u1ea5t c\u00f3 hi\u1ec7u qu\u1ea3. N\u00ean \u0111\u00e1nh gi\u00e1 l\u1ea1i nhu c\u1ea7u \u0111i\u1ec1u tr\u1ecb theo \u0111\u1ecbnh k\u1ef3. M\u1ed9t s\u1ed1 b\u00e1c s\u0129 t\u00e1n th\u00e0nh vi\u1ec7c k\u1ebft h\u1ee3p \u0111\u1ed3ng th\u1eddi t\u00e2m l\u00fd tr\u1ecb li\u1ec7u h\u00e0nh vi \u0111\u1ed1i v\u1edbi nh\u1eefng b\u1ec7nh nh\u00e2n \u0111\u00e3 c\u00f3 k\u1ebft qu\u1ea3 t\u1ed1t khi d\u00f9ng thu\u1ed1c.<\/p>\n<p>B\u1ec7nh nh\u00e2n b\u1ecb suy gan ho\u1eb7c suy th\u1eadn ph\u1ea3i kh\u1edfi \u0111\u1ea7u v\u1edbi li\u1ec1u th\u1ea5p v\u00e0 ph\u1ea3i \u0111\u01b0\u1ee3c theo d\u00f5i c\u1ea9n th\u1eadn.<\/p>\n<p><strong>4.3. Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh:<\/strong><\/p>\n<p>Qu\u00e1 m\u1eabn c\u1ea3m v\u1edbi b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/p>\n<p>Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh d\u00f9ng k\u1ebft h\u1ee3p vi\u00ean Fluvoxamine v\u1edbi c\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf monoamine oxidase (MAOI).<\/p>\n<p>Vi\u1ec7c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Fluvoxamine c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c b\u1eaft \u0111\u1ea7u:<\/p>\n<p>&#8211; 2 tu\u1ea7n sau khi ng\u01b0ng d\u00f9ng ch\u1ea5t \u1ee9c ch\u1ebf MAO kh\u00f4ng thu\u1eadn ngh\u1ecbch, ho\u1eb7c<\/p>\n<p>&#8211; v\u00e0o ng\u00e0y ti\u1ebfp theo sau khi ng\u01b0ng d\u00f9ng ch\u1ea5t \u1ee9c ch\u1ebf MAO thu\u1eadn ngh\u1ecbch (v\u00ed d\u1ee5 moclobemide).<\/p>\n<p>Ph\u1ea3i c\u00e1ch \u00edt nh\u1ea5t m\u1ed9t tu\u1ea7n gi\u1eefa th\u1eddi \u0111i\u1ec3m ng\u01b0ng d\u00f9ng Fluvoxamine v\u00e0 th\u1eddi \u0111i\u1ec3m kh\u1edfi \u0111\u1ea7u d\u00f9ng b\u1ea5t k\u1ef3 ch\u1ea5t \u1ee9c ch\u1ebf MAO n\u00e0o.<\/p>\n<p><strong>4.4 Th\u1eadn tr\u1ecdng:<\/strong><\/p>\n<p>B\u1ec7nh nh\u00e2n tr\u1ea7m c\u1ea3m v\u1ed1n c\u00f3 khuynh h\u01b0\u1edbng d\u1ec5 t\u1ef1 t\u1eed, \u0111i\u1ec1u n\u00e0y c\u00f3 th\u1ec3 k\u00e9o d\u00e0i cho \u0111\u1ebfn khi c\u00f3 s\u1ef1 thuy\u00ean gi\u1ea3m b\u1ec7nh \u0111\u00e1ng k\u1ec3.<\/p>\n<p>B\u1ec7nh nh\u00e2n b\u1ecb suy gan ho\u1eb7c suy th\u1eadn ph\u1ea3i kh\u1edfi \u0111\u1ea7u v\u1edbi li\u1ec1u th\u1ea5p v\u00e0 ph\u1ea3i \u0111\u01b0\u1ee3c theo d\u00f5i c\u1ea9n th\u1eadn. Hi\u1ebfm khi, \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Fluvoxamine c\u00f3 li\u00ean quan v\u1edbi t\u0103ng enzyme gan, ph\u1ea7n l\u1edbn k\u00e8m theo c\u00e1c tri\u1ec7u ch\u1ee9ng l\u00e2m s\u00e0ng. Trong nh\u1eefng tr\u01b0\u1eddng h\u1ee3p n\u00e0y ph\u1ea3i ng\u01b0ng \u0111i\u1ec1u tr\u1ecb.<\/p>\n<p>M\u1eb7c d\u00f9 Fluvoxamine kh\u00f4ng c\u00f3 \u0111\u1eb7c t\u00ednh g\u00e2y co gi\u1eadt trong c\u00e1c nghi\u00ean c\u1ee9u \u1edf \u0111\u1ed9ng v\u1eadt th\u00ed nghi\u1ec7m, c\u1ea7n th\u1eadn tr\u1ecdng khi d\u00f9ng thu\u1ed1c n\u00e0y cho nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed b\u1ecb co gi\u1eadt. N\u1ebfu c\u00f3 c\u00e1c c\u01a1n \u0111\u1ed9ng kinh x\u1ea3y ra th\u00ec ph\u1ea3i ng\u01b0ng \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Fluvoxamine.<\/p>\n<p>\u0110\u00e3 c\u00f3 b\u00e1o c\u00e1o trong m\u1ed9t s\u1ed1 r\u1ea5t \u00edt tr\u01b0\u1eddng h\u1ee3p, s\u1ef1 ph\u00e1t tri\u1ec3n h\u1ed9i ch\u1ee9ng serotonin li\u00ean quan v\u1edbi vi\u1ec7c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Fluvoxamine, \u0111\u1eb7c bi\u1ec7t l\u00e0 khi d\u00f9ng k\u1ebft h\u1ee3p v\u1edbi c\u00e1c thu\u1ed1c g\u00e2y ti\u1ebft serotonin kh\u00e1c v\u00e0 h\u1ed9i ch\u1ee9ng n\u00e0y bi\u1ebfn m\u1ea5t t\u00f9y theo s\u1ef1 ng\u01b0ng thu\u1ed1c v\u00e0\/ho\u1eb7c \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng.<\/p>\n<p>C\u00e1c d\u1eef li\u1ec7u nghi\u00ean c\u1ee9u tr\u00ean ng\u01b0\u1eddi cao tu\u1ed5i kh\u00f4ng cho th\u1ea5y s\u1ef1 kh\u00e1c bi\u1ec7t c\u00f3 \u00fd ngh\u0129a v\u1ec1 l\u00e2m s\u00e0ng so v\u1edbi ng\u01b0\u1eddi tr\u1ebb khi d\u00f9ng li\u1ec1u th\u00f4ng th\u01b0\u1eddng h\u00e0ng ng\u00e0y. Tuy nhi\u00ean, \u1edf ng\u01b0\u1eddi cao tu\u1ed5i vi\u1ec7c t\u0103ng li\u1ec1u n\u00ean ch\u1eadm h\u01a1n v\u00e0 ph\u1ea3i lu\u00f4n lu\u00f4n th\u1eadn tr\u1ecdng khi chu\u1ea9n li\u1ec1u.<\/p>\n<p>Fluvoxamine c\u00f3 th\u1ec3 l\u00e0m ch\u1eadm nh\u1ecbp tim kh\u00f4ng \u0111\u00e1ng k\u1ec3 (2-6 nh\u1ecbp\/ph\u00fat).<\/p>\n<p>Do c\u00f2n thi\u1ebfu c\u00e1c d\u1eef li\u1ec7u l\u00e2m s\u00e0ng n\u00ean kh\u00f4ng khuy\u1ebfn c\u00e1o d\u00f9ng Fluvoxamine \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb tr\u1ea7m c\u1ea3m cho tr\u1ebb em.<\/p>\n<p>\u0110\u00e3 c\u00f3 c\u00e1c b\u00e1o c\u00e1o v\u1ec1 ch\u1ea3y m\u00e1u d\u01b0\u1edbi da b\u1ea5t th\u01b0\u1eddng nh\u01b0 b\u1ea7m m\u00e1u v\u00e0 ban xu\u1ea5t huy\u1ebft do c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf t\u00e1i thu nh\u1eadn serotonin ch\u1ecdn l\u1ecdc (SSRI). C\u1ea7n th\u1eadn tr\u1ecdng \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n \u0111ang d\u00f9ng c\u00e1c thu\u1ed1c SSRI, \u0111\u1eb7c bi\u1ec7t l\u00e0 khi d\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi nh\u1eefng thu\u1ed1c \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn ch\u1ee9c n\u0103ng ti\u1ec3u c\u1ea7u (v\u00ed d\u1ee5 c\u00e1c thu\u1ed1c ch\u1ed1ng lo\u1ea1n th\u1ea7n kh\u00f4ng \u0111i\u1ec3n h\u00ecnh, phenothiazine, ph\u1ea7n l\u1edbn c\u00e1c thu\u1ed1c ch\u1ed1ng tr\u1ea7m c\u1ea3m 3 v\u00f2ng (TCA), aspirin, c\u00e1c thu\u1ed1c kh\u00e1ng vi\u00eam kh\u00f4ng steroid (NSAID) c\u0169ng nh\u01b0 \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 ti\u1ec1n s\u1eed r\u1ed1i lo\u1ea1n ch\u1ea3y m\u00e1u.<\/p>\n<p><strong>T\u00e1c \u0111\u1ed9ng c\u1ee7a thu\u1ed1c tr\u00ean ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/strong><\/p>\n<p>Fluvoxamine v\u1edbi li\u1ec1u \u0111\u1ebfn 150 mg cho th\u1ea5y kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng l\u00ean k\u1ef9 n\u0103ng t\u00e2m th\u1ea7n v\u1eadn \u0111\u1ed9ng li\u00ean quan v\u1edbi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c \u1edf nh\u1eefng ng\u01b0\u1eddi t\u00ecnh nguy\u1ec7n kh\u1ecfe m\u1ea1nh. Tuy nhi\u00ean bu\u1ed3n ng\u1ee7 \u0111\u00e3 \u0111\u01b0\u1ee3c ghi nh\u1eadn trong khi \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Fluvoxamine. V\u00ec v\u1eady c\u1ea7n th\u1eadn tr\u1ecdng cho \u0111\u1ebfn khi x\u00e1c \u0111\u1ecbnh \u0111\u01b0\u1ee3c \u0111\u00e1p \u1ee9ng c\u1ee7a t\u1eebng c\u00e1 nh\u00e2n \u0111\u1ed1i v\u1edbi thu\u1ed1c.<\/p>\n<p><script src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-5528370293090692\" async=\"\" crossorigin=\"anonymous\"><\/script><ins class=\"adsbygoogle\" style=\"display: block; text-align: center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-5528370293090692\" data-ad-slot=\"8909623906\"><\/ins><script> (adsbygoogle = window.adsbygoogle || []).push({}); <\/script><\/p>\n<p><strong>4.5 S\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa:<\/strong><\/p>\n<p><em>X\u1ebfp h\u1ea1ng c\u1ea3nh b\u00e1o<\/em><\/p>\n<p>AU TGA pregnancy category: C<\/p>\n<p>US FDA pregnancy category: C<\/p>\n<p><em>Th\u1eddi k\u1ef3 mang thai:<\/em><\/p>\n<p>C\u00e1c nghi\u00ean c\u1ee9u v\u1ec1 sinh s\u1ea3n \u1edf \u0111\u1ed9ng v\u1eadt th\u00ed nghi\u1ec7m v\u1edbi li\u1ec1u cao cho th\u1ea5y kh\u00f4ng c\u00f3 b\u1eb1ng ch\u1ee9ng v\u1ec1 suy gi\u1ea3m kh\u1ea3 n\u0103ng sinh s\u1ea3n ho\u1eb7c sinh qu\u00e1i thai \u1edf con. Tuy nhi\u00ean, ph\u1ea3i th\u1eadn tr\u1ecdng khi d\u00f9ng b\u1ea5t k\u1ef3 thu\u1ed1c n\u00e0o trong khi c\u00f3 thai.<\/p>\n<p><em>Th\u1eddi k\u1ef3 cho con b\u00fa:<\/em><\/p>\n<p>M\u1ed9t s\u1ed1 l\u01b0\u1ee3ng nh\u1ecf Fluvoxamine \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft qua s\u1eefa m\u1eb9. V\u00ec v\u1eady kh\u00f4ng \u0111\u01b0\u1ee3c d\u00f9ng thu\u1ed1c n\u00e0y \u1edf ph\u1ee5 n\u1eef \u0111ang cho con b\u00fa.<\/p>\n<p><strong>4.6 T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n (ADR):<\/strong><\/p>\n<p>Bu\u1ed3n n\u00f4n, \u0111\u00f4i khi k\u00e8m theo n\u00f4n, l\u00e0 tri\u1ec7u ch\u1ee9ng th\u01b0\u1eddng g\u1eb7p nh\u1ea5t khi \u0111i\u1ec1u tr\u1ecb b\u1eb1ng Fluvoxamine. T\u00e1c d\u1ee5ng ph\u1ee5 n\u00e0y th\u01b0\u1eddng gi\u1ea3m trong hai tu\u1ea7n \u0111\u1ea7u d\u00f9ng thu\u1ed1c. Nh\u1eefng t\u00e1c d\u1ee5ng ph\u1ee5 kh\u00e1c \u0111\u01b0\u1ee3c ghi nh\u1ead\u00ean trong c\u00e1c nghi\u00ean c\u1ee9u l\u00e2m s\u00e0ng \u1edf nh\u1eefng t\u1ea7n su\u1ea5t \u0111\u01b0\u1ee3c li\u1ec7t k\u00ea d\u01b0\u1edbi \u0111\u00e2y, th\u01b0\u1eddng c\u00f3 li\u00ean quan \u0111\u1ebfn b\u1ec7nh tr\u1ea7m c\u1ea3m v\u00e0 kh\u00f4ng nh\u1ea5t thi\u1ebft li\u00ean quan \u0111\u1ebfn vi\u1ec7c \u0111i\u1ec1u tr\u1ecb.<\/p>\n<p><em>Th\u01b0\u1eddng g\u1eb7p (t\u1ea7n su\u1ea5t 1-5%):<\/em><\/p>\n<p>C\u01a1 th\u1ec3: Suy nh\u01b0\u1ee3c, nh\u1ee9c \u0111\u1ea7u, kh\u00f3 \u1edf.<\/p>\n<p>Tim m\u1ea1ch: \u0110\u00e1nh tr\u1ed1ng ng\u1ef1c\/Nh\u1ecbp tim nhanh.<\/p>\n<p>H\u1ec7 ti\u00eau h\u00f3a: \u0110au b\u1ee5ng, ch\u00e1n \u0103n, t\u00e1o b\u00f3n, ti\u00eau ch\u1ea3y, kh\u00f4 mi\u1ec7ng, kh\u00f3 ti\u00eau.<\/p>\n<p>H\u1ec7 th\u1ea7n kinh: K\u00edch \u0111\u1ed9ng, lo \u00e2u, cho\u00e1ng v\u00e1ng, m\u1ea5t ng\u1ee7, c\u0103ng th\u1eb3ng, bu\u1ed3n ng\u1ee7, run.<\/p>\n<p>Da: Ra m\u1ed3 h\u00f4i.<\/p>\n<p><em>\u00cdt g\u1eb7p (t\u1ea7n su\u1ea5t &lt; 1%):<\/em><\/p>\n<p>Tim m\u1ea1ch: H\u1ea1 huy\u1ebft \u00e1p (t\u01b0 th\u1ebf \u0111\u1ee9ng).<\/p>\n<p>C\u01a1 x\u01b0\u01a1ng: \u0110au kh\u1edbp, \u0111au c\u01a1.<\/p>\n<p>H\u1ec7 th\u1ea7n kinh: M\u1ea5t \u0111i\u1ec1u h\u00f2a, l\u00fa l\u1eabn, c\u00e1c tri\u1ec7u ch\u1ee9ng ngo\u1ea1i th\u00e1p, \u1ea3o gi\u00e1c.<\/p>\n<p>Ni\u1ec7u sinh d\u1ee5c: Xu\u1ea5t tinh b\u1ea5t th\u01b0\u1eddng (ch\u1eadm).<\/p>\n<p>Da: Ban, ng\u1ee9a.<\/p>\n<p><em>Hi\u1ebfm g\u1eb7p (t\u1ea7n su\u1ea5t &lt; 0,1%):<\/em><\/p>\n<p>H\u1ec7 ti\u00eau h\u00f3a: Ch\u1ee9c n\u0103ng gan b\u1ea5t th\u01b0\u1eddng.<\/p>\n<p>H\u1ec7 th\u1ea7n kinh: Co gi\u1eadt, c\u01a1n h\u01b0ng c\u1ea3m.<\/p>\n<p>Ni\u1ec7u sinh d\u1ee5c: Ti\u1ebft nhi\u1ec1u s\u1eefa.<\/p>\n<p>Da: Nh\u1ea1y c\u1ea3m v\u1edbi \u00e1nh s\u00e1ng.<\/p>\n<p>C\u0169ng nh\u01b0 c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf t\u00e1i thu nh\u1eadn serotonin ch\u1ecdn l\u1ecdc kh\u00e1c, hi\u1ebfm g\u1eb7p h\u1ea1 natri m\u00e1u v\u00e0 th\u01b0\u1eddng h\u1ed3i ph\u1ee5c sau khi ng\u1eebng Fluvoxamine. M\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p c\u00f3 th\u1ec3 l\u00e0 do h\u1ed9i ch\u1ee9ng ti\u1ebft hormone kh\u00e1ng l\u1ee3i ni\u1ec7u kh\u00f4ng ph\u00f9 h\u1ee3p. \u0110a s\u1ed1 b\u00e1o c\u00e1o li\u00ean quan \u0111\u1ebfn nh\u1eefng b\u1ec7nh nh\u00e2n cao tu\u1ed5i.<\/p>\n<p>Xu\u1ea5t huy\u1ebft: xem ph\u1ea7n Ch\u00fa y\u1ebf \u0111\u1ec1 ph\u00f2ng v\u00e0 Th\u1eadn tr\u1ecdng l\u00fac d\u00f9ng.<\/p>\n<p>\u0110\u00f4i khi l\u00ean c\u00e2n ho\u1eb7c gi\u1ea3m c\u00e2n c\u0169ng \u0111\u00e3 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o.<\/p>\n<p>C\u00e1c ph\u1ea3n \u1ee9ng do ng\u1eebng thu\u1ed1c bao g\u1ed3m d\u1ecb c\u1ea3m, nh\u1ee9c \u0111\u1ea7u, bu\u1ed3n n\u00f4n, cho\u00e1ng v\u00e1ng, lo \u00e2u l\u00e0 nh\u1eefng tr\u01b0\u1eddng h\u1ee3p hi\u1ebfm \u0111\u00e3 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o sau khi \u0111\u1ed9t ng\u1ed9t ng\u1eebng d\u00f9ng Fluvoxamine. Nh\u1eefng ph\u1ea3n \u1ee9ng n\u00e0y th\u01b0\u1eddng nh\u1eb9, t\u1ef1 gi\u1edbi h\u1ea1n, v\u00e0 kh\u00f4ng nh\u1ea5t thi\u1ebft c\u00f3 ngh\u0129a l\u00e0 ph\u1ee5 thu\u1ed9c thu\u1ed1c. N\u00ean gi\u1ea3m li\u1ec1u d\u1ea7n d\u1ea7n tr\u01b0\u1edbc khi ng\u1eebng \u0111i\u1ec1u tr\u1ecb.<\/p>\n<p>M\u1ed9t s\u1ed1 bi\u1ec3u hi\u1ec7n n\u00f3i tr\u00ean c\u00f3 th\u1ec3 l\u00e0 tri\u1ec7u ch\u1ee9ng c\u1ee7a b\u1ec7nh tr\u1ea7m c\u1ea3m v\u00e0 kh\u00f4ng nh\u1ea5t thi\u1ebft l\u00e0 do thu\u1ed1c g\u00e2y ra.<\/p>\n<p><em>Th\u00f4ng b\u00e1o cho B\u00e1c s\u0129 nh\u1eefng t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n g\u1eb7p ph\u1ea3i khi s\u1eed d\u1ee5ng thu\u1ed1c.<\/em><\/p>\n<p><strong>4.7 H\u01b0\u1edbng d\u1eabn c\u00e1ch x\u1eed tr\u00ed ADR:<\/strong><\/p>\n<p>Ng\u1eebng s\u1eed d\u1ee5ng thu\u1ed1c. V\u1edbi c\u00e1c ph\u1ea3n \u1ee9ng b\u1ea5t l\u1ee3i nh\u1eb9, th\u01b0\u1eddng ch\u1ec9 c\u1ea7n ng\u1eebng thu\u1ed1c. Tr\u01b0\u1eddng h\u1ee3p m\u1eabn c\u1ea3m n\u1eb7ng ho\u1eb7c ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng, c\u1ea7n ti\u1ebfn h\u00e0nh \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3 (gi\u1eef tho\u00e1ng kh\u00ed v\u00e0 d\u00f9ng epinephrin, th\u1edf oxygen, d\u00f9ng kh\u00e1ng histamin, corticoid&#8230;).<\/p>\n<p><strong>4.8 T\u01b0\u01a1ng t\u00e1c v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1c:<\/strong><\/p>\n<p>Kh\u00f4ng \u0111\u01b0\u1ee3c d\u00f9ng ph\u1ed1i h\u1ee3p Fluvoxamine v\u1edbi c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf MAO (MAOI).<\/p>\n<p>Fluvoxamine c\u00f3 th\u1ec3 k\u00e9o d\u00e0i s\u1ef1 th\u1ea3i tr\u1eeb c\u00e1c thu\u1ed1c \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a qua s\u1ef1 oxy h\u00f3a \u1edf gan. T\u01b0\u01a1ng t\u00e1c c\u00f3 \u00fd ngh\u0129a l\u00e2m s\u00e0ng c\u00f3 th\u1ec3 x\u1ea3y ra khi ph\u1ed1i h\u1ee3p v\u1edbi nh\u1eefng thu\u1ed1c c\u00f3 ch\u1ec9 s\u1ed1 \u0111i\u1ec1u tr\u1ecb h\u1eb9p (v\u00ed d\u1ee5 warfarin, phenytoin, theophylline, cyclosporin, tacrine, methadone, clozapine v\u00e0 carbamazepin).<\/p>\n<p>N\u1ed3ng \u0111\u1ed9 trong huy\u1ebft t\u01b0\u01a1ng c\u1ee7a benzodiazepine \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a qua oxy h\u00f3a \u1edf gan c\u00f3 th\u1ec3 t\u0103ng l\u00ean khi d\u00f9ng ph\u1ed1i h\u1ee3p v\u1edbi Fluvoxamine.<\/p>\n<p>\u0110\u00e3 c\u00f3 b\u00e1o c\u00e1o v\u1ec1 s\u1ef1 gia t\u0103ng n\u1ed3ng \u0111\u1ed9 trong huy\u1ebft t\u01b0\u01a1ng tr\u01b0\u1edbc \u0111\u00e2y \u1ed5n \u0111\u1ecbnh c\u1ee7a c\u00e1c thu\u1ed1c ch\u1ed1ng tr\u1ea7m c\u1ea3m 3 v\u00f2ng v\u00e0 c\u00e1c thu\u1ed1c an th\u1ea7n &#8211; nh\u1eefng ch\u1ea5t \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a ph\u1ea7n l\u1edbn qua cytochrome P450 1A2, khi d\u00f9ng c\u00f9ng v\u1edbi Fluvoxamine. Kh\u00f4ng khuy\u1ebfn c\u00e1o d\u00f9ng ph\u1ed1i h\u1ee3p nh\u1eefng thu\u1ed1c n\u00e0y v\u1edbi Fluvoxamine.<\/p>\n<p>M\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p ri\u00eang l\u1ebb nhi\u1ec5m \u0111\u1ed9c tim \u0111\u00e3 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o khi d\u00f9ng k\u1ebft h\u1ee3p Fluvoxamine v\u1edbi thioridazine.<\/p>\n<p>Trong c\u00e1c nghi\u00ean c\u1ee9u v\u1ec1 t\u01b0\u01a1ng t\u00e1c thu\u1ed1c, nh\u1eadn th\u1ea5y n\u1ed3ng \u0111\u1ed9 propranolol trong huy\u1ebft t\u01b0\u01a1ng t\u0103ng l\u00ean khi d\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi Fluvoxamine. V\u00ec v\u1eady n\u00ean gi\u1ea3m li\u1ec1u propranolol khi k\u00ea \u0111\u01a1n c\u00f9ng Fluvoxamine.<\/p>\n<p>Khi d\u00f9ng Fluvoxamine \u0111\u1ed3ng th\u1eddi v\u1edbi warfarin trong hai tu\u1ea7n, n\u1ed3ng \u0111\u1ed9 warfarin trong huy\u1ebft t\u01b0\u01a1ng t\u0103ng l\u00ean \u0111\u00e1ng k\u1ec3 v\u00e0 th\u1eddi gian prothrombin k\u00e9o d\u00e0i. Do \u0111\u00f3 b\u1ec7nh nh\u00e2n d\u00f9ng thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng m\u00e1u c\u00f9ng v\u1edbi Fluvoxamine ph\u1ea3i \u0111\u01b0\u1ee3c theo d\u00f5i th\u1eddi gian prothrombin v\u00e0 \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng cho ph\u00f9 h\u1ee3p.<\/p>\n<p>Kh\u00f4ng c\u00f3 t\u01b0\u01a1ng t\u00e1c n\u00e0o \u0111\u01b0\u1ee3c ghi nh\u1eadn gi\u1eefa Fluvoxamine v\u1edbi digoxin v\u00e0 atenolol. Fluvoxamine \u0111\u01b0\u1ee3c d\u00f9ng k\u1ebft h\u1ee3p v\u1edbi lithium \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh n\u1eb7ng v\u00e0 c\u00e1c b\u1ec7nh nh\u00e2n kh\u00e1ng thu\u1ed1c. Tuy nhi\u00ean, lithium (v\u00e0 c\u00f3 th\u1ec3 c\u1ea3 tryptophan) l\u00e0m t\u0103ng t\u00e1c d\u1ee5ng g\u00e2y ti\u1ebft serotonin c\u1ee7a Fluvoxamine, v\u00ec v\u1eady c\u1ea7n th\u1eadn tr\u1ecdng khi d\u00f9ng ph\u1ed1i h\u1ee3p lithium v\u1edbi Fluvoxamine. C\u00e1c t\u00e1c d\u1ee5ng g\u00e2y ti\u1ebft serotonin c\u0169ng c\u00f3 th\u1ec3 t\u0103ng l\u00ean khi Fluvoxamine \u0111\u01b0\u1ee3c d\u00f9ng ph\u1ed1i h\u1ee3p v\u1edbi c\u00e1c thu\u1ed1c g\u00e2y ti\u1ebft serotonin kh\u00e1c (k\u1ec3 c\u1ea3 sumatriptan v\u00e0 c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf t\u00e1i thu nh\u1eadn serotonin ch\u1ecdn l\u1ecdc-SSRI). Trong m\u1ed9t s\u1ed1 r\u1ea5t \u00edt tr\u01b0\u1eddng h\u1ee3p \u0111i\u1ec1u n\u00e0y c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn h\u1ed9i ch\u1ee9ng serotonin.<\/p>\n<p>C\u0169ng nh\u01b0 v\u1edbi c\u00e1c thu\u1ed1c t\u00e2m th\u1ea7n kh\u00e1c, b\u1ec7nh nh\u00e2n n\u00ean tr\u00e1nh u\u1ed1ng r\u01b0\u1ee3u trong khi d\u00f9ng Fluvoxamine.<\/p>\n<p><script src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-5528370293090692\" async=\"\" crossorigin=\"anonymous\"><\/script><ins class=\"adsbygoogle\" style=\"display: block; text-align: center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-5528370293090692\" data-ad-slot=\"8909623906\"><\/ins><script> (adsbygoogle = window.adsbygoogle || []).push({}); <\/script><\/p>\n<p><strong>4.9 Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed:<\/strong><\/p>\n<p><em>Tri\u1ec7u ch\u1ee9ng:<\/em><\/p>\n<p>C\u00e1c tri\u1ec7u ch\u1ee9ng bao g\u1ed3m r\u1ed1i lo\u1ea1n d\u1ea1 d\u00e0y-ru\u1ed9t (bu\u1ed3n n\u00f4n, n\u00f4n v\u00e0 ti\u00eau ch\u1ea3y), bu\u1ed3n ng\u1ee7, cho\u00e1ng v\u00e1ng. C\u00e1c hi\u1ec7n t\u01b0\u1ee3ng tim m\u1ea1ch (tim \u0111\u1eadp nhanh, tim \u0111\u1eadp ch\u1eadm, h\u1ea1 huy\u1ebft \u00e1p), r\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng gan, co gi\u1eadt v\u00e0 h\u00f4n m\u00ea c\u0169ng \u0111\u00e3 \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o. Fluvoxamine c\u00f3 gi\u1edbi h\u1ea1n an to\u00e0n r\u1ed9ng trong qu\u00e1 li\u1ec1u. K\u1ec3 t\u1eeb khi Fluvoxamine \u0111\u01b0\u1ee3c l\u01b0u h\u00e0nh tr\u00ean th\u1ecb tr\u01b0\u1eddng, r\u1ea5t hi\u1ebfm g\u1eb7p b\u00e1o c\u00e1o t\u1eed vong do d\u00f9ng Fluvoxamine qu\u00e1 li\u1ec1u. Li\u1ec1u Fluvoxamine cao nh\u1ea5t m\u00e0 b\u1ec7nh nh\u00e2n \u0111\u00e3 u\u1ed1ng l\u00e0 12 g. B\u1ec7nh nh\u00e2n n\u00e0y \u0111\u00e3 h\u1ed3i ph\u1ee5c ho\u00e0n to\u00e0n. \u0110\u00f4i khi, c\u00e1c bi\u1ebfn ch\u1ee9ng nghi\u00eam tr\u1ecdng h\u01a1n \u0111\u00e3 \u0111\u01b0\u1ee3c ghi nh\u1eadn trong tr\u01b0\u1eddng h\u1ee3p c\u1ed1 \u00fd d\u00f9ng qu\u00e1 li\u1ec1u Fluvoxamine k\u1ebft h\u1ee3p v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1c.<\/p>\n<p><em>\u0110i\u1ec1u tr\u1ecb:<\/em><\/p>\n<p>Kh\u00f4ng c\u00f3 thu\u1ed1c gi\u1ea3i \u0111\u1ed9c \u0111\u1eb7c hi\u1ec7u \u0111\u1ed1i v\u1edbi Fluvoxamine. Trong tr\u01b0\u1eddng h\u1ee3p qu\u00e1 li\u1ec1u ph\u1ea3i r\u1eeda d\u1ea1 d\u00e0y c\u00e0ng s\u1edbm c\u00e0ng t\u1ed1t sau khi u\u1ed1ng v\u00e0 ph\u1ea3i \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng. S\u1eed d\u1ee5ng than ho\u1ea1t nhi\u1ec1u l\u1ea7n c\u0169ng \u0111\u01b0\u1ee3c khuy\u1ebfn c\u00e1o. L\u1ee3i ni\u1ec7u hay th\u1ea9m t\u00e1ch kh\u00f4ng ch\u1eafc mang l\u1ea1i k\u1ebft qu\u1ea3.<\/p>\n<p><strong>5. C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c :<\/strong><\/p>\n<p><strong>5.1. D\u01b0\u1ee3c l\u1ef1c h\u1ecdc:<\/strong><\/p>\n<p>Fluvoxamine \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb r\u1ed1i lo\u1ea1n \u00e1m \u1ea3nh c\u01b0\u1ee1ng ch\u1ebf (OCD). Thu\u1ed1c gi\u00fap gi\u1ea3m vi\u1ec7c suy ngh\u0129 li\u00ean t\u1ee5c\/nh\u1eefng suy ngh\u0129 kh\u00f4ng mong mu\u1ed1n (\u00e1m \u1ea3nh) v\u00e0 h\u00e0nh vi th\u1ef1c hi\u1ec7n c\u00e1c h\u00e0nh \u0111\u1ed9ng l\u1eb7p \u0111i l\u1eb7p l\u1ea1i (m\u1ed9t c\u00e1ch b\u1eaft bu\u1ed9c nh\u01b0 r\u1eeda tay, \u0111\u1ebfm, ki\u1ec3m tra) g\u00e2y r\u1ed1i lo\u1ea1n sinh ho\u1ea1t h\u00e0ng ng\u00e0y. Fluvoxamine \u0111\u01b0\u1ee3c bi\u1ebft \u0111\u1ebfn nh\u01b0 m\u1ed9t ch\u1ea5t \u1ee9c ch\u1ebf t\u00e1i h\u1ea5p thu serotonin c\u00f3 ch\u1ecdn l\u1ecdc (SSRI). Thu\u1ed1c ho\u1ea1t \u0111\u1ed9ng b\u1eb1ng c\u00e1ch gi\u00fap kh\u00f4i ph\u1ee5c l\u1ea1i s\u1ef1 c\u00e2n b\u1eb1ng cho ch\u1ea5t t\u1ef1 nhi\u00ean trong n\u00e3o (serotonin).<\/p>\n<p>Thu\u1ed1c c\u0169ng c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb tr\u1ea7m c\u1ea3m v\u00e0 c\u0103ng th\u1eb3ng r\u1ed1i lo\u1ea1n sau ch\u1ea5n th\u01b0\u01a1ng.<\/p>\n<p><strong><em>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng: <\/em><\/strong><\/p>\n<p>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng c\u1ee7a Fluvoxamine \u0111\u01b0\u1ee3c cho l\u00e0 li\u00ean quan \u0111\u1ebfn s\u1ef1 \u1ee9c ch\u1ebf t\u00e1i thu nh\u1eadn serotonin ch\u1ecdn l\u1ecdc \u1edf n\u01a1ron n\u00e3o. Fluvoxamine \u1ea3nh h\u01b0\u1edfng r\u1ea5t \u00edt \u0111\u1ebfn qu\u00e1 tr\u00ecnh ti\u1ebft noradrenaline. C\u00e1c nghi\u00ean c\u1ee9u v\u1ec1 s\u1ef1 g\u1eafn v\u00e0o th\u1ee5 th\u1ec3 \u0111\u00e3 ch\u1ee9ng minh r\u1eb1ng Fluvoxamine c\u00f3 kh\u1ea3 n\u0103ng g\u1eafn kh\u00f4ng \u0111\u00e1ng k\u1ec3 v\u00e0o c\u00e1c th\u1ee5 th\u1ec3 alpha-adrenaline, beta-adrenaline, histamin, muscarine cholin, dopamin ho\u1eb7c serotonin.<\/p>\n<p><strong>[XEM T\u1ea0I \u0110\u00c2Y]<\/strong><\/p>\n<p><strong>5.2. D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc:<\/strong><\/p>\n<p>Fluvoxamine \u0111\u01b0\u1ee3c h\u1ea5p thu ho\u00e0n to\u00e0n qua \u0111\u01b0\u1eddng u\u1ed1ng. N\u1ed3ng \u0111\u1ed9 t\u1ed1i \u0111a trong huy\u1ebft t\u01b0\u01a1ng \u0111\u1ea1t \u0111\u01b0\u1ee3c sau khi u\u1ed1ng 3-8 gi\u1edd. Th\u1eddi gian b\u00e1n h\u1ee7y trung b\u00ecnh trong huy\u1ebft t\u01b0\u01a1ng kho\u1ea3ng 13-15 gi\u1edd sau khi u\u1ed1ng li\u1ec1u \u0111\u01a1n v\u00e0 k\u00e9o d\u00e0i h\u01a1n m\u1ed9t ch\u00fat (17-22 gi\u1edd) khi d\u00f9ng c\u00e1c li\u1ec1u ti\u1ebfp t\u1ee5c, khi \u0111\u00f3 n\u1ed3ng \u0111\u1ed9 trong huy\u1ebft t\u01b0\u01a1ng \u1edf tr\u1ea1ng th\u00e1i \u1ed5n \u0111\u1ecbnh th\u01b0\u1eddng \u0111\u1ea1t \u0111\u01b0\u1ee3c trong v\u00f2ng 10-14 ng\u00e0y.<\/p>\n<p>Fluvoxamine chuy\u1ec3n h\u00f3a m\u1ea1nh qua gan ch\u1ee7 y\u1ebfu qua ph\u1ea3n \u1ee9ng oxy h\u00f3a kh\u1eed methyl th\u00e0nh \u00edt nh\u1ea5t 9 ch\u1ea5t chuy\u1ec3n h\u00f3a \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft qua th\u1eadn. Hai ch\u1ea5t chuy\u1ec3n h\u00f3a ch\u00ednh c\u00f3 ho\u1ea1t t\u00ednh d\u01b0\u1ee3c l\u00fd kh\u00f4ng \u0111\u00e1ng k\u1ec3. C\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a kh\u00e1c th\u00ec kh\u00f4ng c\u00f3 ho\u1ea1t t\u00ednh d\u01b0\u1ee3c l\u00fd. In vitro, Fluvoxamine g\u1eafn v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng ng\u01b0\u1eddi kho\u1ea3ng 80%.<\/p>\n<p><strong>5.3 Gi\u1ea3i th\u00edch: <\/strong><\/p>\n<p>Ch\u01b0a c\u00f3 th\u00f4ng tin. \u0110ang c\u1eadp nh\u1eadt.<\/p>\n<p><strong>5.4 Thay th\u1ebf thu\u1ed1c : <\/strong><\/p>\n<p>Ch\u01b0a c\u00f3 th\u00f4ng tin. \u0110ang c\u1eadp nh\u1eadt.<\/p>\n<p><strong><em>*L\u01b0u \u00fd:<\/em><\/strong><\/p>\n<p><strong><em>C\u00e1c th\u00f4ng tin v\u1ec1 thu\u1ed1c tr\u00ean Pharmog.com ch\u1ec9 mang t\u00ednh ch\u1ea5t tham kh\u1ea3o &#8211; Khi d\u00f9ng thu\u1ed1c c\u1ea7n tuy\u1ec7t \u0111\u1ed1i tu\u00e2n theo theo h\u01b0\u1edbng d\u1eabn c\u1ee7a B\u00e1c s\u0129 <\/em><\/strong><\/p>\n<p><strong><em>Ch\u00fang t\u00f4i kh\u00f4ng ch\u1ecbu tr\u00e1ch nhi\u1ec7m v\u1ec1 b\u1ea5t c\u1ee9 h\u1eadu qu\u1ea3 n\u00e0o x\u1ea3y ra do t\u1ef1 \u00fd d\u00f9ng thu\u1ed1c d\u1ef1a theo c\u00e1c th\u00f4ng tin tr\u00ean Pharmog.com<\/em><\/strong><\/p>\n<p><script src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-5528370293090692\" async=\"\" crossorigin=\"anonymous\"><\/script><ins class=\"adsbygoogle\" style=\"display: block; text-align: center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-5528370293090692\" data-ad-slot=\"8909623906\"><\/ins><script> (adsbygoogle = window.adsbygoogle || []).push({}); <\/script><\/p>\n<p><strong>6. Ph\u1ea7n th\u00f4ng tin k\u00e8m theo c\u1ee7a thu\u1ed1c:<\/strong><\/p>\n<p><strong>6.1. Danh m\u1ee5c t\u00e1 d\u01b0\u1ee3c:<\/strong><\/p>\n<p>Talc, sugar spheres, ammonio methacrylate copolymer type B, dibutyl sebacate, red iron oxide, FD&amp;C Blue No. 2, titanium dioxide, gelatin , Opacode Grey..<\/p>\n<p><strong>6.2. T\u01b0\u01a1ng k\u1ef5 :<\/strong><\/p>\n<p>Kh\u00f4ng \u00e1p d\u1ee5ng.<\/p>\n<p><strong>6.3. B\u1ea3o qu\u1ea3n: <\/strong><\/p>\n<p>N\u01a1i kh\u00f4, tr\u00e1nh \u00e1nh s\u00e1ng, nhi\u1ec7t \u0111\u1ed9 d\u01b0\u1edbi 30\u00b0C.<\/p>\n<p><strong>6.4. Th\u00f4ng tin kh\u00e1c :<\/strong><\/p>\n<p>Kh\u00f4ng c\u00f3.<\/p>\n<p><strong>6.5 T\u00e0i li\u1ec7u tham kh\u1ea3o:<\/strong><\/p>\n<p>D\u01b0\u1ee3c Th\u01b0 Qu\u1ed1c Gia Vi\u1ec7t Nam<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>1. T\u00ean ho\u1ea1t ch\u1ea5t v\u00e0 bi\u1ec7t d\u01b0\u1ee3c: Ho\u1ea1t ch\u1ea5t : Fluvoxamine maleate Ph\u00e2n lo\u1ea1i: Thu\u00f4\u0301c \u1ee9c ch\u1ebf t\u00e1i h\u1ea5p thu serotonin ch\u1ecdn l\u1ecdc (SSRIs) Nh\u00f3m ph\u00e1p l\u00fd: Thu\u1ed1c k\u00ea \u0111\u01a1n ETC \u2013 (Ethical drugs, prescription drugs, Prescription only medicine) M\u00e3 ATC (Anatomical Therapeutic Chemical): N06AB08. Brand name: Luvox Generic : Fluvoxamine ,\u00a0Fanzini 2. D\u1ea1ng b\u00e0o [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":23537,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[2],"tags":[816],"class_list":["post-1788","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-thuoc-a-z","tag-fluvoxamine"],"_links":{"self":[{"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/posts\/1788","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/comments?post=1788"}],"version-history":[{"count":4,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/posts\/1788\/revisions"}],"predecessor-version":[{"id":52387,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/posts\/1788\/revisions\/52387"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/media\/23537"}],"wp:attachment":[{"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/media?parent=1788"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/categories?post=1788"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/tags?post=1788"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}