{"id":17318,"date":"2020-03-30T09:47:53","date_gmt":"2020-03-30T02:47:53","guid":{"rendered":"https:\/\/pharmog.com\/wp\/?p=17318"},"modified":"2025-01-08T21:20:13","modified_gmt":"2025-01-08T14:20:13","slug":"cetirizine-vincezin","status":"publish","type":"post","link":"https:\/\/pharmog.com\/wp\/cetirizine-vincezin\/","title":{"rendered":"Cetirizine &#8211; Vincezin"},"content":{"rendered":"<p><strong>1. T\u00ean ho\u1ea1t ch\u1ea5t v\u00e0 bi\u1ec7t d\u01b0\u1ee3c: <\/strong><\/p>\n<p><strong><em>Ho\u1ea1t ch\u1ea5t :<\/em> <a href=\"https:\/\/pharmog.com\/wp\/cetirizine\/\">Cetirizine<\/a><\/strong><\/p>\n<p><strong><em>Ph\u00e2n lo\u1ea1i: <\/em><\/strong><em>Thu\u1ed1c \u0111\u1ed1i kh\u00e1ng th\u1ee5 th\u1ec3 histamine H1..<\/em><\/p>\n<p><strong><em>Nh\u00f3m<\/em><\/strong> <strong><em>ph\u00e1p l\u00fd: <\/em><\/strong><em>Thu\u1ed1c kh\u00f4ng k\u00ea \u0111\u01a1n OTC \u2013 (Over the counter)<\/em><\/p>\n<p><strong><em>M\u00e3 ATC<\/em><\/strong> (Anatomical Therapeutic Chemical): R06AE07.<\/p>\n<p><strong><em>Bi\u1ec7t d\u01b0\u1ee3c g\u1ed1c:<\/em> <a href=\"https:\/\/pharmog.com\/wp\/cetirizine-zyrtec\/\">ZYRTEC<\/a><\/strong><\/p>\n<p><strong><em>Bi\u1ec7t d\u01b0\u1ee3c:<\/em><\/strong> Vincezin<\/p>\n<p><strong><em>H\u00e3ng s\u1ea3n xu\u1ea5t <\/em><\/strong>: C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m V\u0129nh Ph\u00fac<\/p>\n<p><script src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-5528370293090692\" async=\"\" crossorigin=\"anonymous\"><\/script><ins class=\"adsbygoogle\" style=\"display: block; text-align: center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-5528370293090692\" data-ad-slot=\"8909623906\"><\/ins><script> (adsbygoogle = window.adsbygoogle || []).push({}); <\/script><\/p>\n<p><strong>2. D\u1ea1ng b\u00e0o ch\u1ebf &#8211; H\u00e0m l\u01b0\u1ee3ng: <\/strong><\/p>\n<p><strong><em>D\u1ea1ng thu\u1ed1c v\u00e0 h\u00e0m l\u01b0\u1ee3ng<\/em><\/strong><\/p>\n<p>Vi\u00ean n\u00e9n: 10 mg.<\/p>\n<p><strong><em>Thu\u1ed1c tham kh\u1ea3o:<\/em><\/strong><\/p>\n<table>\n<tbody>\n<tr>\n<td colspan=\"2\"><strong><em>VINCEZIN<\/em><\/strong><\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\"><em>M\u1ed7i vi\u00ean n\u00e9n ch\u1ee9a<\/em><\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td>Cetirizine<\/td>\n<td>&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.<\/td>\n<td>10 mg<\/td>\n<\/tr>\n<tr>\n<td>T\u00e1 d\u01b0\u1ee3c<\/td>\n<td>&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.<\/td>\n<td>v\u1eeba \u0111\u1ee7 (Xem m\u1ee5c 6.1)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><img loading=\"lazy\" decoding=\"async\" width=\"685\" height=\"421\" class=\"wp-image-17319\" src=\"https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2020\/03\/word-image-152.png\" srcset=\"https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2020\/03\/word-image-152.png 685w, https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2020\/03\/word-image-152-300x184.png 300w, https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2020\/03\/word-image-152-600x369.png 600w, https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2020\/03\/word-image-152-260x160.png 260w\" sizes=\"auto, (max-width: 685px) 100vw, 685px\" \/><\/p>\n<p><strong>3. Video by Pharmog:<\/strong><\/p>\n<p><strong>[VIDEO D\u01af\u1ee2C L\u00dd]<\/strong><\/p>\n<div class=\"ast-oembed-container \" style=\"height: 100%;\"><iframe loading=\"lazy\" title=\"[Pharmog SS1 - T\u1eadp 06] - D\u01b0\u1ee3c l\u00fd v\u1ec1 thu\u1ed1c kh\u00e1ng Histamin H1\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/fAp4TM3XUKA?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe><\/div>\n<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<\/p>\n<p>\u25ba K\u1ecbch B\u1ea3n: PharmogTeam<\/p>\n<p>\u25ba Youtube: https:\/\/www.youtube.com\/c\/pharmog<\/p>\n<p>\u25ba Facebook: https:\/\/www.facebook.com\/pharmog\/<\/p>\n<p>\u25ba Group : H\u1ed9i nh\u1eefng ng\u01b0\u1eddi m\u00ea d\u01b0\u1ee3c l\u00fd<\/p>\n<p>\u25ba Instagram : https:\/\/www.instagram.com\/pharmogvn\/<\/p>\n<p>\u25ba Website: pharmog.com<\/p>\n<p><strong>4. \u1ee8ng d\u1ee5ng l\u00e2m s\u00e0ng: <\/strong><\/p>\n<p><strong>4.1. Ch\u1ec9 \u0111\u1ecbnh:<\/strong><\/p>\n<p>Vincezin \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng vi\u00eam m\u0169i d\u1ecb \u1ee9ng dai d\u1eb3ng, vi\u00eam m\u0169i d\u1ecb \u1ee9ng theo m\u00f9a, m\u00e0y \u0111ay m\u1ea1n t\u00ednh v\u00f4 c\u0103n \u1edf ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em tr\u00ean 12 tu\u1ed5i v\u00e0 vi\u00eam m\u0169i d\u1ecb \u1ee9ng theo m\u00f9a \u1edf tr\u1ebb em tr\u00ean 12 tu\u1ed5i; vi\u00eam k\u1ebft m\u1ea1c d\u1ecb \u1ee9ng.<\/p>\n<p><strong>4.2. Li\u1ec1u d\u00f9ng &#8211; C\u00e1ch d\u00f9ng:<\/strong><\/p>\n<p><strong><em>C\u00e1ch d\u00f9ng<\/em><\/strong> :<\/p>\n<p>Thu\u1ed1c d\u00f9ng qua \u0111\u01b0\u1eddng u\u1ed1ng<\/p>\n<p><strong><em>Li\u1ec1u d\u00f9ng:<\/em><\/strong><\/p>\n<p>Ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em t\u1eeb 6 tu\u1ed5i tr\u1edf l\u00ean u\u1ed1ng 1 vi\u00ean 10 mg\/ng\u00e0y. Hi\u1ec7n nay, ch\u01b0a c\u00f3 s\u1ed1 li\u1ec7u n\u00e0o g\u1ee3i \u00fd c\u1ea7n ph\u1ea3i gi\u1ea3m li\u1ec1u \u1edf ng\u01b0\u1eddi cao tu\u1ed5i. Tuy v\u1eady, ph\u1ea3i gi\u1ea3m n\u1eeda li\u1ec1u \u1edf ng\u01b0\u1eddi suy th\u1eadn<\/p>\n<p><strong>4.3. Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh:<\/strong><\/p>\n<p>Nh\u1eefng ng\u01b0\u1eddi c\u00f3 ti\u1ec1n s\u1eed d\u1ecb \u1ee9ng v\u1edbi cetirizin, v\u1edbi hydroxyzin.<\/p>\n<p><strong>4.4 Th\u1eadn tr\u1ecdng:<\/strong><\/p>\n<p>C\u1ea7n ph\u1ea3i \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u \u1edf ng\u01b0\u1eddi suy th\u1eadn v\u1eeba ho\u1eb7c n\u1eb7ng v\u00e0 ng\u01b0\u1eddi \u0111ang th\u1ea9m ph\u00e2n th\u1eadn nh\u00e2n t\u1ea1o<\/p>\n<p>C\u1ea7n \u0111i\u1ec1u ch\u1ec9nh li\u1ec1u \u1edf ng\u01b0\u1eddi suy gan.<\/p>\n<p>Tr\u00e1nh d\u00f9ng \u0111\u1ed3ng th\u1eddi cetirizin v\u1edbi r\u01b0\u1ee3u v\u00e0 c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf th\u1ea7n kinh trung \u01b0\u01a1ng, v\u00ec l\u00e0m t\u0103ng th\u00eam t\u00e1c d\u1ee5ng c\u1ee7a c\u00e1c thu\u1ed1c n\u00e0y.<\/p>\n<p><strong>T\u00e1c \u0111\u1ed9ng c\u1ee7a thu\u1ed1c tr\u00ean ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/strong><\/p>\n<p>\u1ede m\u1ed9t s\u1ed1 ng\u01b0\u1eddi b\u1ec7nh s\u1eed d\u1ee5ng ceftirizin c\u00f3 hi\u1ec7n t\u01b0\u1ee3ng ng\u1ee7 g\u00e0, do v\u1eady n\u00ean th\u1eadn tr\u1ecdng khi l\u00e1i xe, ho\u1eb7c v\u1eadn h\u00e0nh m\u00e1y, v\u00ec d\u1ec5 g\u00e2y nguy hi\u1ec3m.<\/p>\n<p><strong>4.5 S\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa:<\/strong><\/p>\n<p><em>X\u1ebfp h\u1ea1ng c\u1ea3nh b\u00e1o<\/em><\/p>\n<p>AU TGA pregnancy category: B2<\/p>\n<p>US FDA pregnancy category: NA<\/p>\n<p><em>Th\u1eddi k\u1ef3 mang thai:<\/em><\/p>\n<p>Tuy cetirizin kh\u00f4ng g\u00e2y qu\u00e1i thai \u1edf \u0111\u1ed9ng v\u1eadt, nh\u01b0ng kh\u00f4ng c\u00f3 nh\u1eefng nghi\u00ean c\u1ee9u \u0111\u1ea7y \u0111\u1ee7 tr\u00ean ng\u01b0\u1eddi mang thai, cho n\u00ean kh\u00f4ng n\u00ean d\u00f9ng khi c\u00f3 thai.<\/p>\n<p><em>Th\u1eddi k\u1ef3 cho con b\u00fa:<\/em><\/p>\n<p>Cetirizin b\u00e0i ti\u1ebft qua s\u1eefa m\u1eb9, v\u00ec v\u1eady ng\u01b0\u1eddi cho con b\u00fa kh\u00f4ng n\u00ean d\u00f9ng thu\u1ed1c.<\/p>\n<p><script src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-5528370293090692\" async=\"\" crossorigin=\"anonymous\"><\/script><ins class=\"adsbygoogle\" style=\"display: block; text-align: center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-5528370293090692\" data-ad-slot=\"8909623906\"><\/ins><script> (adsbygoogle = window.adsbygoogle || []).push({}); <\/script><\/p>\n<p><strong>4.6 T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n (ADR):<\/strong><\/p>\n<p><em>Th\u01b0\u1eddng g\u1eb7p, ADR &gt; 1\/100:<\/em><\/p>\n<p>Hay g\u1eb7p nh\u1ea5t l\u00e0 hi\u1ec7n t\u01b0\u1ee3ng ng\u1ee7 g\u00e0. T\u1ec9 l\u1ec7 g\u00e2y n\u00ean ph\u1ee5 thu\u1ed9c v\u00e0o li\u1ec1u d\u00f9ng.<\/p>\n<p>Ngo\u00e0i ra thu\u1ed1c c\u00f2n g\u00e2y m\u1ec7t m\u1ecfi, kh\u00f4 mi\u1ec7ng, vi\u00eam h\u1ecdng, ch\u00f3ng m\u1eb7t, nh\u1ee9c \u0111\u1ea7u, bu\u1ed3n n\u00f4n.<\/p>\n<p><em>\u00cdt g\u1eb7p, 1\/1000 &lt; ADR &lt; 1\/100:<\/em><\/p>\n<p>Ch\u00e1n \u0103n ho\u1eb7c t\u0103ng th\u00e8m \u0103n, b\u00ed ti\u1ec3u, \u0111\u1ecf b\u1eebng, t\u0103ng ti\u1ebft n\u01b0\u1edbc b\u1ecdt.<\/p>\n<p><em>Hi\u1ebfm g\u1eb7p, ADR &lt; 1\/1000<\/em><\/p>\n<p>Thi\u1ebfu m\u00e1u, tan m\u00e1u, gi\u1ea3m ti\u1ec3u c\u1ea7u, h\u1ea1 huy\u1ebft \u00e1p n\u1eb7ng, cho\u00e1ng ph\u1ea3n v\u1ec7, vi\u00eam gan, \u1ee9 m\u1eadt, vi\u00eam c\u1ea7u th\u1eadn.<\/p>\n<p><em>Th\u00f4ng b\u00e1o cho B\u00e1c s\u0129 nh\u1eefng t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n g\u1eb7p ph\u1ea3i khi s\u1eed d\u1ee5ng thu\u1ed1c.<\/em><\/p>\n<p><strong>4.7 H\u01b0\u1edbng d\u1eabn c\u00e1ch x\u1eed tr\u00ed ADR:<\/strong><\/p>\n<p>Ng\u1eebng s\u1eed d\u1ee5ng thu\u1ed1c. V\u1edbi c\u00e1c ph\u1ea3n \u1ee9ng b\u1ea5t l\u1ee3i nh\u1eb9, th\u01b0\u1eddng ch\u1ec9 c\u1ea7n ng\u1eebng thu\u1ed1c. Tr\u01b0\u1eddng h\u1ee3p m\u1eabn c\u1ea3m n\u1eb7ng ho\u1eb7c ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng, c\u1ea7n ti\u1ebfn h\u00e0nh \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3 (gi\u1eef tho\u00e1ng kh\u00ed v\u00e0 d\u00f9ng epinephrin, th\u1edf oxygen, d\u00f9ng kh\u00e1ng histamin, corticoid&#8230;).<\/p>\n<p><strong>4.8 T\u01b0\u01a1ng t\u00e1c v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1c:<\/strong><\/p>\n<p>\u0110\u1ebfn nay ch\u01b0a th\u1ea5y t\u01b0\u01a1ng t\u00e1c \u0111\u00e1ng k\u1ec3 v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1c. \u0110\u1ed9 thanh th\u1ea3i cetirizin gi\u1ea3m nh\u1eb9 khi u\u1ed1ng c\u00f9ng 400 mg theophylin.<\/p>\n<p><strong>4.9 Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed:<\/strong><\/p>\n<p>Tri\u1ec7u ch\u1ee9ng c\u1ee7a qu\u00e1 li\u1ec1u l\u00e0: ng\u1ee7 g\u00e0 \u1edf ng\u01b0\u1eddi l\u1edbn; \u1edf tr\u1ebb em c\u00f3 th\u1ec3 b\u1ecb k\u00edch \u0111\u1ed9ng.<\/p>\n<p>Khi qu\u00e1 li\u1ec1u nghi\u00eam tr\u1ecdng c\u1ea7n g\u00e2y n\u00f4n v\u00e0 r\u1eeda d\u1ea1 d\u00e0y c\u00f9ng v\u1edbi c\u00e1c ph\u01b0\u01a1ng ph\u00e1p h\u1ed7 tr\u1ee3. \u0110\u1ebfn nay, ch\u01b0a c\u00f3 thu\u1ed1c gi\u1ea3i \u0111\u1ed9c \u0111\u1eb7c hi\u1ec7u.<\/p>\n<p><script src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-5528370293090692\" async=\"\" crossorigin=\"anonymous\"><\/script><ins class=\"adsbygoogle\" style=\"display: block; text-align: center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-5528370293090692\" data-ad-slot=\"8909623906\"><\/ins><script> (adsbygoogle = window.adsbygoogle || []).push({}); <\/script><\/p>\n<p><strong>5. C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c :<\/strong><\/p>\n<p><strong>5.1. D\u01b0\u1ee3c l\u1ef1c h\u1ecdc:<\/strong><\/p>\n<p>Cetirizin l\u00e0 thu\u1ed1c kh\u00e1ng histamin m\u1ea1nh c\u00f3 t\u00e1c d\u1ee5ng ch\u1ed1ng d\u1ecb \u1ee9ng, nh\u01b0ng kh\u00f4ng g\u00e2y bu\u1ed3n ng\u1ee7 \u1edf li\u1ec1u d\u01b0\u1ee3c l\u00fd. Cetirizin c\u00f3 t\u00e1c d\u1ee5ng \u0111\u1ed1i kh\u00e1ng ch\u1ecdn l\u1ecdc \u1edf th\u1ee5 th\u1ec3 H1, nh\u01b0ng h\u1ea7u nh\u01b0 kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng \u0111\u1ebfn c\u00e1c th\u1ee5 th\u1ec3 kh\u00e1c, do v\u1eady h\u1ea7u nh\u01b0 kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng \u0111\u1ed1i kh\u00e1ng acetylcholin v\u00e0 kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng \u0111\u1ed1i kh\u00e1ng serotonin.<\/p>\n<p>Cetirizin \u1ee9c ch\u1ebf giai \u0111o\u1ea1n s\u1edbm c\u1ee7a ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng qua trung gian histamin v\u00e0 c\u0169ng l\u00e0m gi\u1ea3m s\u1ef1 di d\u1eddi c\u1ee7a c\u00e1c t\u1ebf b\u00e0o vi\u00eam v\u00e0 gi\u1ea3m gi\u1ea3i ph\u00f3ng c\u00e1c ch\u1ea5t trung gian \u1edf giai \u0111o\u1ea1n mu\u1ed9n c\u1ee7a ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng.<\/p>\n<p><strong><em>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng: <\/em><\/strong><\/p>\n<p>Cetirizin, m\u1ed9t ch\u1ea5t chuy\u1ec3n h\u00f3a c\u1ee7a hydroxyzine tr\u00ean ng\u01b0\u1eddi, l\u00e0 ch\u1ea5t kh\u00e1ng th\u1ee5 th\u1ec3 H1 ngo\u1ea1i vi m\u1ea1nh v\u00e0 ch\u1ecdn l\u1ecdc. C\u00e1c nghi\u00ean c\u1ee9u v\u1ec1 g\u1eafn k\u1ebft v\u1edbi th\u1ee5 th\u1ec3 in vitro cho th\u1ea5y thu\u1ed1c kh\u00f4ng c\u00f3 \u00e1i l\u1ef1c \u0111o \u0111\u01b0\u1ee3c v\u1edbi th\u1ee5 th\u1ec3 n\u00e0o kh\u00e1c ngo\u00e0i th\u1ee5 th\u1ec3 H1.<\/p>\n<p>Th\u1ef1c nghi\u1ec7m ex vivo tr\u00ean chu\u1ed9t cho th\u1ea5y cetirizin d\u00f9ng \u0111\u01b0\u1eddng to\u00e0n th\u00e2n chi\u1ebfm gi\u1eef kh\u00f4ng \u0111\u00e1ng k\u1ec3 c\u00e1c th\u1ee5 th\u1ec3 H1 \u1edf n\u00e3o.<\/p>\n<p>Ngo\u00e0i t\u00e1c d\u1ee5ng kh\u00e1ng th\u1ee5 th\u1ec3 H1, cetirizin \u0111\u00e3 ch\u1ee9ng t\u1ecf c\u00f3 ho\u1ea1t t\u00ednh kh\u00e1ng d\u1ecb \u1ee9ng: v\u1edbi li\u1ec1u 10mg m\u1ed9t ho\u1eb7c hai l\u1ea7n m\u1ed7i ng\u00e0y, cetirizin \u1ee9c ch\u1ebf s\u1ef1 t\u1eadp k\u1ebft c\u00e1c t\u1ebf b\u00e0o vi\u00eam \u1edf giai \u0111o\u1ea1n mu\u1ed9n, \u0111\u1eb7c bi\u1ec7t l\u00e0 b\u1ea1ch c\u1ea7u \u00e1i toan, \u1edf da v\u00e0 k\u1ebft m\u1ea1c c\u1ee7a c\u00e1c \u0111\u1ed1i t\u01b0\u1ee3ng d\u1ecb \u1ee9ng c\u00f3 ti\u1ebfp x\u00fac v\u1edbi kh\u00e1ng nguy\u00ean, v\u00e0 v\u1edbi li\u1ec1u 30mg\/ng\u00e0y \u1ee9c ch\u1ebf s\u1ef1 di chuy\u1ec3n c\u1ee7a b\u1ea1ch c\u1ea7u \u00e1i toan trong d\u1ecbch r\u1eeda ph\u1ebf qu\u1ea3n &#8211; ph\u1ebf nang trong giai \u0111o\u1ea1n mu\u1ed9n c\u1ee7a co th\u1eaft ph\u1ebf qu\u1ea3n do ng\u01b0\u1eddi m\u1eafc b\u1ec7nh hen h\u00edt ph\u1ea3i d\u1ecb \u1ee9ng nguy\u00ean. Ngo\u00e0i ra, cetirizin c\u00f2n \u1ee9c ch\u1ebf ph\u1ea3n \u1ee9ng vi\u00eam giai \u0111o\u1ea1n mu\u1ed9n tr\u00ean b\u1ec7nh nh\u00e2n m\u1eafc m\u00e0y \u0111ay m\u1ea1n t\u00ednh khi ti\u00eam kallikrein trong da. Thu\u1ed1c \u0111\u1ed3ng th\u1eddi c\u0169ng c\u00f3 t\u00e1c d\u1ee5ng l\u00e0m gi\u1ea3m s\u1ef1 xu\u1ea5t hi\u1ec7n c\u1ee7a c\u00e1c ph\u1ea7n t\u1eed g\u1eafn k\u1ebft nh\u01b0 ICAM-1 v\u00e0 VCAM-1 &#8211; l\u00e0 nh\u1eefng d\u1ea5u ch\u1ec9 \u0111i\u1ec3m c\u1ee7a ph\u1ea3n \u1ee9ng vi\u00eam d\u1ecb \u1ee9ng.<\/p>\n<p>Nghi\u00ean c\u1ee9u tr\u00ean ng\u01b0\u1eddi t\u00ecnh nguy\u1ec7n kh\u1ecfe m\u1ea1nh cho th\u1ea5y cetirizin li\u1ec1u 5mg v\u00e0 10mg \u1ee9c ch\u1ebf m\u1ea1nh ph\u1ea3n \u1ee9ng m\u00e0y \u0111ay v\u00e0 ban \u0111\u1ecf do n\u1ed3ng \u0111\u1ed9 r\u1ea5t cao c\u1ee7a histamine trong da g\u00e2y n\u00ean. Sau khi u\u1ed1ng li\u1ec1u \u0111\u01a1n 10mg, thu\u1ed1c b\u1eaft \u0111\u1ea7u c\u00f3 t\u00e1c d\u1ee5ng trong v\u00f2ng 20 ph\u00fat tr\u00ean 50% \u0111\u1ed1i t\u01b0\u1ee3ng th\u1eed nghi\u1ec7m v\u00e0 trong v\u00f2ng 1 gi\u1edd tr\u00ean 95% \u0111\u1ed1i t\u01b0\u1ee3ng. T\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c duy tr\u00ec \u00edt nh\u1ea5t 24 gi\u1edd sau khi u\u1ed1ng m\u1ed9t li\u1ec1u \u0111\u01a1n. Trong m\u1ed9t nghi\u00ean c\u1ee9u k\u00e9o d\u00e0i 35 ng\u00e0y tr\u00ean tr\u1ebb em t\u1eeb 5 \u0111\u1ebfn 12 tu\u1ed5i, ng\u01b0\u1eddi ta kh\u00f4ng th\u1ea5y c\u00f3 s\u1ef1 dung n\u1ea1p \u0111\u1ed1i v\u1edbi t\u00e1c d\u1ee5ng kh\u00e1ng histamine (ch\u1ed1ng m\u00e0y \u0111ay v\u00e0 ban \u0111\u1ecf) c\u1ee7a cetirizin. Sau khi d\u00f9ng nhi\u1ec1u l\u1ea7n cetirizin, khi ng\u01b0ng \u0111i\u1ec1u tr\u1ecb, da ph\u1ee5c h\u1ed3i l\u1ea1i ph\u1ea3n \u1ee9ng b\u00ecnh th\u01b0\u1eddng v\u1edbi histamine trong v\u00f2ng 3 ng\u00e0y<\/p>\n<p><a href=\"https:\/\/www.youtube.com\/watch?v=fAp4TM3XUKA\"><strong>[XEM T\u1ea0I \u0110\u00c2Y]<\/strong><\/a><\/p>\n<p><strong>5.2. D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc:<\/strong><\/p>\n<p>N\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong m\u00e1u \u1edf mirc 0,3 pg\/ml sau 30 \u0111\u1ebfn 60 ph\u00fat khi u\u1ed1ng 1 li\u1ec1u 10 mg.<\/p>\n<p>Th\u1eddi gian b\u00e1n th\u1ea3i x\u1ea5p x\u1ec9 11 gi\u1edd.<\/p>\n<p>H\u1ea5p thu thu\u1ed1c kh\u00f4ng thay \u0111\u1ed5i gi\u1eefa c\u00e1c c\u00e1 th\u1ec3.<\/p>\n<p>\u0110\u1ed9 thanh th\u1ea3i \u1edf th\u1eadn l\u00e0 30 ml\/ph\u00fat.<\/p>\n<p>Cetirizin li\u00ean k\u1ebft m\u1ea1nh v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng (kho\u1ea3ng 934).<\/p>\n<p><strong> 5.3 Gi\u1ea3i th\u00edch: <\/strong><\/p>\n<p>Ch\u01b0a c\u00f3 th\u00f4ng tin. \u0110ang c\u1eadp nh\u1eadt.<\/p>\n<p><strong>5.4 Thay th\u1ebf thu\u1ed1c : <\/strong><\/p>\n<p>Ch\u01b0a c\u00f3 th\u00f4ng tin. \u0110ang c\u1eadp nh\u1eadt.<\/p>\n<p><strong><em>*L\u01b0u \u00fd:<\/em><\/strong><\/p>\n<p><strong><em>C\u00e1c th\u00f4ng tin v\u1ec1 thu\u1ed1c tr\u00ean Pharmog.com ch\u1ec9 mang t\u00ednh ch\u1ea5t tham kh\u1ea3o &#8211; Khi d\u00f9ng thu\u1ed1c c\u1ea7n tuy\u1ec7t \u0111\u1ed1i tu\u00e2n theo theo h\u01b0\u1edbng d\u1eabn c\u1ee7a B\u00e1c s\u0129 <\/em><\/strong><\/p>\n<p><strong><em>Ch\u00fang t\u00f4i kh\u00f4ng ch\u1ecbu tr\u00e1ch nhi\u1ec7m v\u1ec1 b\u1ea5t c\u1ee9 h\u1eadu qu\u1ea3 n\u00e0o x\u1ea3y ra do t\u1ef1 \u00fd d\u00f9ng thu\u1ed1c d\u1ef1a theo c\u00e1c th\u00f4ng tin tr\u00ean Pharmog.com<\/em><\/strong><\/p>\n<p><script src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-5528370293090692\" async=\"\" crossorigin=\"anonymous\"><\/script><ins class=\"adsbygoogle\" style=\"display: block; text-align: center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-5528370293090692\" data-ad-slot=\"8909623906\"><\/ins><script> (adsbygoogle = window.adsbygoogle || []).push({}); <\/script><\/p>\n<p><strong>6. Ph\u1ea7n th\u00f4ng tin k\u00e8m theo c\u1ee7a thu\u1ed1c:<\/strong><\/p>\n<p><strong>6.1. Danh m\u1ee5c t\u00e1 d\u01b0\u1ee3c:<\/strong><\/p>\n<p>Amidon, lactose, magnesi stearat, aerosil, hypromellose, ethylcellulose, titan dioxyd, PEG 6000, b\u1ed9t talc, ethanol 96%, n\u01b0\u1edbc tinh khi\u1ebft v\u1eeba \u0111\u1ee7 1 vi\u00ean.<\/p>\n<p><strong>6.2. T\u01b0\u01a1ng k\u1ef5 :<\/strong><\/p>\n<p>Kh\u00f4ng \u00e1p d\u1ee5ng.<\/p>\n<p><strong>6.3. B\u1ea3o qu\u1ea3n: <\/strong><\/p>\n<p>N\u01a1i kh\u00f4, tr\u00e1nh \u00e1nh s\u00e1ng, nhi\u1ec7t \u0111\u1ed9 d\u01b0\u1edbi 30\u00b0C.<\/p>\n<p><strong>6.4. Th\u00f4ng tin kh\u00e1c :<\/strong><\/p>\n<p>D\u1eef li\u1ec7u ti\u1ec1n l\u00e2m s\u00e0ng kh\u00f4ng cho th\u1ea5y nguy hi\u1ec3m \u0111\u1eb7c bi\u1ec7t cho ng\u01b0\u1eddi d\u1ef1a tr\u00ean c\u00e1c nghi\u00ean c\u1ee9u quy \u01b0\u1edbc v\u1ec1 an to\u00e0n d\u01b0\u1ee3c l\u00fd h\u1ecdc, \u0111\u1ed9c t\u00ednh li\u1ec1u l\u1eb7p l\u1ea1i, \u0111\u1ed9t bi\u1ebfn gen, nguy c\u01a1 g\u00e2y ung th\u01b0, \u0111\u1ed9c t\u00ednh tr\u00ean kh\u1ea3 n\u0103ng sinh s\u1ea3n.<\/p>\n<p><strong>6.5 T\u00e0i li\u1ec7u tham kh\u1ea3o:<\/strong><\/p>\n<p>D\u01b0\u1ee3c Th\u01b0 Qu\u1ed1c Gia Vi\u1ec7t Nam<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>1. T\u00ean ho\u1ea1t ch\u1ea5t v\u00e0 bi\u1ec7t d\u01b0\u1ee3c: Ho\u1ea1t ch\u1ea5t : Cetirizine Ph\u00e2n lo\u1ea1i: Thu\u1ed1c \u0111\u1ed1i kh\u00e1ng th\u1ee5 th\u1ec3 histamine H1.. Nh\u00f3m ph\u00e1p l\u00fd: Thu\u1ed1c kh\u00f4ng k\u00ea \u0111\u01a1n OTC \u2013 (Over the counter) M\u00e3 ATC (Anatomical Therapeutic Chemical): R06AE07. Bi\u1ec7t d\u01b0\u1ee3c g\u1ed1c: ZYRTEC Bi\u1ec7t d\u01b0\u1ee3c: Vincezin H\u00e3ng s\u1ea3n xu\u1ea5t : C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":17319,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[419],"tags":[598],"class_list":["post-17318","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-biet-duoc","tag-cetirizine"],"_links":{"self":[{"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/posts\/17318","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/comments?post=17318"}],"version-history":[{"count":4,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/posts\/17318\/revisions"}],"predecessor-version":[{"id":50690,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/posts\/17318\/revisions\/50690"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/media\/17319"}],"wp:attachment":[{"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/media?parent=17318"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/categories?post=17318"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/tags?post=17318"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}