{"id":16444,"date":"2020-02-17T09:07:59","date_gmt":"2020-02-17T02:07:59","guid":{"rendered":"https:\/\/pharmog.com\/wp\/?p=16444"},"modified":"2025-01-08T21:28:50","modified_gmt":"2025-01-08T14:28:50","slug":"cefixime-egofixim","status":"publish","type":"post","link":"https:\/\/pharmog.com\/wp\/cefixime-egofixim\/","title":{"rendered":"Cefixime &#8211; Egofixim"},"content":{"rendered":"<p><strong>1. T\u00ean ho\u1ea1t ch\u1ea5t v\u00e0 bi\u1ec7t d\u01b0\u1ee3c: <\/strong><\/p>\n<p><strong><em>Ho\u1ea1t ch\u1ea5t :<\/em> <a href=\"https:\/\/pharmog.com\/wp\/cefixime\/\">Cefixime<\/a><\/strong><\/p>\n<p><strong><em>Ph\u00e2n lo\u1ea1i: <\/em><\/strong><em>Thu\u1ed1c kh\u00e1ng sinh cephalosporin th\u1ebf h\u1ec7 3.<\/em><\/p>\n<p><strong><em>Nh\u00f3m<\/em><\/strong> <strong><em>ph\u00e1p l\u00fd: <\/em><\/strong><em>Thu\u1ed1c k\u00ea \u0111\u01a1n ETC \u2013 (Ethical drugs, prescription drugs, Prescription only medicine)<\/em><\/p>\n<p><strong><em>M\u00e3 ATC<\/em><\/strong> (Anatomical Therapeutic Chemical): J01DD08.<\/p>\n<p><strong><em>Bi\u1ec7t d\u01b0\u1ee3c g\u1ed1c:<\/em><\/strong><\/p>\n<p><strong><em>Bi\u1ec7t d\u01b0\u1ee3c:<\/em><\/strong> Egofixim<\/p>\n<p><strong><em>H\u00e3ng s\u1ea3n xu\u1ea5t <\/em><\/strong>: C\u00f4ng ty c\u1ed5 ph\u1ea7n d\u01b0\u1ee3c ph\u1ea9m Am Vi<\/p>\n<p><script src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-5528370293090692\" async=\"\" crossorigin=\"anonymous\"><\/script><ins class=\"adsbygoogle\" style=\"display: block; text-align: center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-5528370293090692\" data-ad-slot=\"8909623906\"><\/ins><script> (adsbygoogle = window.adsbygoogle || []).push({}); <\/script><\/p>\n<p><strong>2. D\u1ea1ng b\u00e0o ch\u1ebf &#8211; H\u00e0m l\u01b0\u1ee3ng: <\/strong><\/p>\n<p><strong><em>D\u1ea1ng thu\u1ed1c v\u00e0 h\u00e0m l\u01b0\u1ee3ng<\/em><\/strong><\/p>\n<p>Vi\u00ean Nang \/ vi\u00ean n\u00e9n 100mg, 200 mg;<\/p>\n<p><strong><em>Thu\u1ed1c tham kh\u1ea3o:<\/em><\/strong><\/p>\n<table>\n<tbody>\n<tr>\n<td colspan=\"2\"><strong><em>EGOFIXIM 200<\/em><\/strong><\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\"><em>M\u1ed7i vi\u00ean n\u00e9n c\u00f3 ch\u1ee9a:<\/em><\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td>Cefixime Trihydrate<\/td>\n<td>&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.<\/td>\n<td>200 mg<\/td>\n<\/tr>\n<tr>\n<td>T\u00e1 d\u01b0\u1ee3c<\/td>\n<td>&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.<\/td>\n<td>v\u1eeba \u0111\u1ee7 (Xem m\u1ee5c 6.1)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><img loading=\"lazy\" decoding=\"async\" width=\"423\" height=\"284\" class=\"wp-image-16445\" src=\"https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2020\/02\/word-image-51.png\" srcset=\"https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2020\/02\/word-image-51.png 423w, https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2020\/02\/word-image-51-300x201.png 300w, https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2020\/02\/word-image-51-238x160.png 238w\" sizes=\"auto, (max-width: 423px) 100vw, 423px\" \/><\/p>\n<table>\n<tbody>\n<tr>\n<td colspan=\"2\"><strong><em>EGOFIXIM 100<\/em><\/strong><\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\"><em>M\u1ed7i vi\u00ean n\u00e9n c\u00f3 ch\u1ee9a:<\/em><\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td>Cefixime Trihydrate<\/td>\n<td>&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.<\/td>\n<td>100 mg<\/td>\n<\/tr>\n<tr>\n<td>T\u00e1 d\u01b0\u1ee3c<\/td>\n<td>&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.<\/td>\n<td>v\u1eeba \u0111\u1ee7 (Xem m\u1ee5c 6.1)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><img loading=\"lazy\" decoding=\"async\" width=\"401\" height=\"252\" class=\"wp-image-16446\" src=\"https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2020\/02\/word-image-52.png\" srcset=\"https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2020\/02\/word-image-52.png 401w, https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2020\/02\/word-image-52-300x189.png 300w, https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2020\/02\/word-image-52-255x160.png 255w, https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2020\/02\/word-image-52-318x200.png 318w\" sizes=\"auto, (max-width: 401px) 100vw, 401px\" \/><\/p>\n<p><strong>3. Video by Pharmog:<\/strong><\/p>\n<p><strong>[VIDEO D\u01af\u1ee2C L\u00dd]<\/strong><\/p>\n<div class=\"ast-oembed-container \" style=\"height: 100%;\"><iframe loading=\"lazy\" title=\"[Pharmog SS1 - T\u1eadp 08] - D\u01b0\u1ee3c l\u00fd c\u00e1c thu\u1ed1c kh\u00e1ng sinh\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/0TIIfoiJFwA?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe><\/div>\n<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<\/p>\n<p>\u25ba K\u1ecbch B\u1ea3n: PharmogTeam<\/p>\n<p>\u25ba Youtube: https:\/\/www.youtube.com\/c\/pharmog<\/p>\n<p>\u25ba Facebook: https:\/\/www.facebook.com\/pharmog\/<\/p>\n<p>\u25ba Group : H\u1ed9i nh\u1eefng ng\u01b0\u1eddi m\u00ea d\u01b0\u1ee3c l\u00fd<\/p>\n<p>\u25ba Instagram : https:\/\/www.instagram.com\/pharmogvn\/<\/p>\n<p>\u25ba Website: pharmog.com<\/p>\n<p><strong>4. \u1ee8ng d\u1ee5ng l\u00e2m s\u00e0ng: <\/strong><\/p>\n<p><strong>4.1. Ch\u1ec9 \u0111\u1ecbnh:<\/strong><\/p>\n<p>Tr\u1ecb c\u00e1c nhi\u1ec5m khu\u1ea9n g\u00e2y ra b\u1edfi c\u00e1c ch\u1ee7ng nh\u1ea1y c\u1ea3m: .<\/p>\n<p>Nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng ni\u1ec7u (c\u00f3 v\u00e0 kh\u00f4ng c\u00f3 bi\u1ebfn ch\u1ee9ng), vi\u00eam th\u1eadn v\u00e0 b\u1ec3 th\u1eadn c\u1ea5p t\u00ednh, vi\u00eam b\u00e0ng quang c\u00e2p t\u00ednh.<\/p>\n<p>Nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p, bao g\u1ed3m c\u00e0 vi\u00eam ph\u1ebf qu\u1ea3n v\u00e0 vi\u00eam ph\u1ed5i.<\/p>\n<p>Nhi\u1ec5m tr\u00f9ng tai m\u0169i h\u1ecdng: vi\u00eam xoang, vi\u00eam tai gi\u1eefa, vi\u00eam h\u1ea7u h\u1ecdng, vi\u00eam amidan.<\/p>\n<p>Vi\u00eam t\u00fai m\u1eadt, nhi\u1ec5m khu\u1ea9n \u0111\u01b0\u1eddng m\u1eadt.<\/p>\n<p>S\u1ed1t th\u01b0\u01a1ng h\u00e0n, vi\u00eam kh\u1edbp.<\/p>\n<p>Nhi\u1ec5m khu\u1ea9n ph\u1ee5 khoa, nhi\u1ec5m khu\u00e2n h\u1eadu ph\u1eabu.<\/p>\n<p>B\u1ec7nh l\u1eadu kh\u00f4ng bi\u1ebfn ch\u1ee9ng.<\/p>\n<p><strong> 4.2. Li\u1ec1u d\u00f9ng &#8211; C\u00e1ch d\u00f9ng:<\/strong><\/p>\n<p><strong><em>C\u00e1ch d\u00f9ng<\/em><\/strong> : D\u00f9ng u\u1ed1ng.<\/p>\n<p><strong><em>Li\u1ec1u d\u00f9ng:<\/em><\/strong><\/p>\n<p>Th\u1eddi gian \u0111i\u1ec1u tr\u1ecb t\u1eeb 7 \u2014 14 ng\u00e0y.<\/p>\n<p>Ng\u01b0\u1eddi l\u1edbn, tr\u1ebb em &gt; 12 tu\u1ed5i ho\u1eb7c tr\u1ebb em c\u00f3 tr\u1ecdng l\u01b0\u1ee3ng &gt; 30 kg: li\u1ec1u \u0111i\u1ec1u tr\u1ecb t\u1eeb 200 &#8211; 400 mg\/ng\u00e0y, u\u1ed1ng 1 l\u1ea7n duy nh\u1ea5t ho\u1eb7c chia 2 l\u1ea7n\/ng\u00e0y.<\/p>\n<p>Tr\u1ebb em d\u01b0\u1edbi 12 tu\u1ed5i: 8 mg\/kg\/ng\u00e0y, u\u1ed1ng l l\u1ea7n duy nh\u1ea5t ho\u1eb7c chia 2 l\u1ea7n\/ng\u00e0y.<\/p>\n<p>Li\u1ec1u d\u00f9ng \u1edf b\u1ec7nh nh\u00e2n suy th\u1eadn: t\u00f9y thu\u1ed9c \u0111\u1ed9 thanh th\u1ea3i creatinin.<\/p>\n<p>\u0110\u1ed9 thanh th\u1ea3i creatinin &gt; 60 ml\/ph\u00fat: \u00c1p d\u1ee5ng li\u1ec1u th\u00f4ng th\u01b0\u1eddng.<\/p>\n<p>\u0110\u1ed9 thanh th\u1ea3i creatinin t\u1eeb 21 &#8211; 60 ml\/ph\u00fat ho\u1eb7c b\u1ec7nh nh\u00e2n th\u00e2m ph\u00e2n huy\u1ebft th\u1eadn: N\u00ean d\u00f9ng li\u1ec1u b\u1eb1ng 75% so v\u1edbi li\u1ec1u b\u00ecnh th\u01b0\u1eddng.<\/p>\n<p>\u0110\u1ed9 thanh th\u1ea3i creatinin &lt; 21 ml\/ph\u00fat ho\u1eb7c b\u1ec7nh nh\u00e2n th\u1ea3m ph\u00e2n m\u00e0ng b\u1ee5ng th\u01b0\u1eddng xuy\u00ean: c\u00f3 th\u1ec3 d\u00f9ng li\u1ec1u b\u1eb1ng 50% so v\u1edbi li\u1ec1u b\u00ecnh th\u01b0\u1eddng. Vi\u1ec7c th\u1ea9m ph\u00e2n huy\u1ebft th\u1eadn v\u00e0 th\u1ea9m ph\u00e2n m\u00e0ng b\u1ee5ng kh\u00f4ng th\u1ec3 lo\u1ea1i l\u01b0\u1ee3ng l\u1edbn thu\u1ed1c ra kh\u1ecfi c\u01a1 th\u00ea.<\/p>\n<p><strong>4.3. Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh:<\/strong><\/p>\n<p>B\u1ec7nh nh\u00e2n d\u1ecb \u1ee9ng v\u1edbi kh\u00e1ng sinh nh\u00f3m Cephalosporin v\u00e0 nh\u00f3m Penicilin<\/p>\n<p><strong>4.4 Th\u1eadn tr\u1ecdng:<\/strong><\/p>\n<p>Tr\u01b0\u1edbc khi b\u1eaft \u0111\u1ea7u di\u1ec1u tr\u1ecb b\u1eb1ng cefixim c\u1ea7n \u0111i\u1ec1u tra k\u1ef9 v\u1ec1 ti\u1ec1n s\u1eed d\u1ecb \u1ee9ng c\u1ee7a ng\u01b0\u1eddi b\u1ec7nh \u0111\u1ed1i v\u1edbi penicilin v\u00e0 c\u00e1c cephalosporin kh\u00e1c do c\u00f3 s\u1ef1 qu\u00e1 m\u1eabn ch\u00e9o gi\u1eefa c\u00e1c kh\u00e1ng sinh nh\u00f3m beta-lactam, bao g\u00f4m: penicilin, cephalosphorin v\u00e0 cephamycin. .<\/p>\n<p>C\u1ea7n th\u1eadn tr\u1ecdng khi d\u00f9ng cefixim \u1edf ng\u01b0\u1eddi c\u00f3 ti\u1ec1n s\u1eed b\u1ec7nh \u0111\u01b0\u1eddng ti\u00eau h\u00f3a v\u00e0 vi\u00eam \u0111\u1ea1i tr\u00e0ng, nh\u00e2t l\u00e0 khi d\u00f9ng k\u00e9o d\u00e0i, v\u00ec c\u00f3 th\u1ec3 c\u00f3 nguy c\u01a1 l\u00e0m ph\u00e1t tri\u1ec3n qu\u00e1 m\u1ee9c c\u00e1c vi khu\u1ea9n kh\u00e1ng thu\u1ed1c, \u0111\u1eb7c bi\u1ec7t l\u00e0 Clostridium dificile \u1edf ru\u1ed9t l\u00e0m \u1ec9a ch\u1ea3y n\u1eb7ng c\u1ea7n ph\u1ea3i ng\u1eebng thu\u1ed1c v\u00e0 \u0111i\u1ec1u tr\u1ecb b\u1eb1ng c\u00e1c kh\u00e1ng sinh kh\u00e1c (metronidazol, vancomycin&#8230;). Ngo\u00e0i ra, ia ch\u1ea3y trong 1 &#8211; 2 ng\u00e0y \u0111au ch\u1ee7 y\u1ebfu l\u00e0 do thu\u1ed1c, n\u1ebfu nh\u1eb9 kh\u00f4ng c\u1ea7n ng\u1eebng thu\u1ed1c. Cefixim c\u00f2n l\u00e0m thay \u0111\u1ed5i vi khu\u1ea9n ch\u1ec9 \u1edf ru\u1ed9t.<\/p>\n<p>Li\u1ec1u v\u00e0\/ ho\u1eb7c s\u1ed1 l\u1ea7n \u0111\u01b0a thu\u1ed1c c\u1ea7n ph\u1ea3i gi\u1ea3m \u1edf nh\u1eefng ng\u01b0\u1eddi b\u1ec7nh suy th\u1eadn, bao g\u00f4m c\u1ea3 nh\u1eefng ng\u01b0\u1eddi b\u1ec7nh \u0111ang l\u1ecdc m\u00e1u ngo\u00e0i th\u1eadn do n\u1ed3ng \u0111\u1ed9 cefixim trong huy\u1ebft t\u01b0\u01a1ng \u1edf b\u1ec7nh nh\u00e2n suy th\u1eadn cao h\u01a1n v\u00e0 k\u00e9o d\u00e0i h\u01a1n so v\u1edbi nh\u1eefng ng\u01b0\u1eddi b\u1ec7nh c\u00f3 ch\u1ee9c n\u0103ng th\u1eadn b\u00ecnh th\u01b0\u1eddng. (Xem th\u00eam: Li\u1ec1u d\u00f9ng v\u1edbi ng\u01b0\u1eddi b\u1ec7nh suy th\u1eadn).<\/p>\n<p>\u0110\u1ed1i v\u1edbi tr\u1ebb d\u01b0\u1edbi 6 th\u00e1ng tu\u1ed5i, cho \u0111\u1ebfn nay ch\u01b0a c\u00f3 d\u1eef li\u1ec7u v\u1ec1 \u0111\u1ed9 an to\u00e0n v\u00e0 hi\u1ec7u l\u1ef1c c\u1ee7a cefixim.<\/p>\n<p>\u0110\u1ed1i v\u1edbi ng\u01b0\u1eddi cao tu\u1ed5i: Nh\u00ecn chung kh\u00f4ng c\u1ea7n \u0111i\u1ec1u chinh li\u1ec1u, tr\u1eeb khi c\u00f3 suy gi\u1ea3m ch\u1ee9c n\u0103ng th\u1eadn (\u0111\u1ed9 thanh th\u1ea3i creatinin &lt; 60 ml\/ph\u00fat).<\/p>\n<p><script src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-5528370293090692\" async=\"\" crossorigin=\"anonymous\"><\/script><ins class=\"adsbygoogle\" style=\"display: block; text-align: center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-5528370293090692\" data-ad-slot=\"8909623906\"><\/ins><script> (adsbygoogle = window.adsbygoogle || []).push({}); <\/script><\/p>\n<p><strong>T\u00e1c \u0111\u1ed9ng c\u1ee7a thu\u1ed1c tr\u00ean ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/strong><\/p>\n<p>Ch\u01b0a c\u00f3 nghi\u00ean c\u1ee9u v\u1ec1 t\u00e1c d\u1ee5ng cefixime tr\u00ean kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y. Kh\u00f4ng c\u00f3 b\u1eb1ng ch\u1ee9ng \u0111\u1ec3 n\u00eau \u1ea3nh h\u01b0\u1edfng c\u1ee7a cefixime tr\u00ean nh\u1eefng kh\u1ea3 n\u0103ng n\u00e0y.<\/p>\n<p><strong>4.5 S\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa:<\/strong><\/p>\n<p><em>X\u1ebfp h\u1ea1ng c\u1ea3nh b\u00e1o<\/em><\/p>\n<p>AU TGA pregnancy category: NA<\/p>\n<p>US FDA pregnancy category: B<\/p>\n<p><em>Th\u1eddi k\u1ef3 mang thai:<\/em><\/p>\n<p>Ch\u1ec9 s\u1eed d\u1ee5ng thu\u1ed1c trong th\u1eddi k\u1ef3 c\u00f3 thai n\u1ebfu th\u1eadt c\u1ea7n thi\u1ebft v\u00e0 ph\u1ea3i theo ch\u1ec9 d\u1eabn c\u1ee7a th\u1ea7y thu\u1ed1c<\/p>\n<p><em>Th\u1eddi k\u1ef3 cho con b\u00fa:<\/em><\/p>\n<p>Ch\u01b0a bi\u1ebft r\u00f5 Cefixim c\u00f3 th\u1ea3i tr\u1eeb qua s\u1eefa hay kh\u00f4ng. N\u00ean t\u1ea1m ng\u1eebng cho con b\u00fa trong th\u1eddi gian d\u00f9ng thu\u00f4c<\/p>\n<p><strong>4.6 T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n (ADR):<\/strong><\/p>\n<p>D\u1ea1 d\u00e0y &#8211; ru\u1ed9t: Ti\u00eau ch\u1ea3y, ph\u00e2n l\u1ecfng, \u0111au b\u1ee5ng, kh\u00f3 ti\u00eau, bu\u1ed3n n\u00f4n v\u00e0 n\u00f4n.<\/p>\n<p>Ph\u1ea3n \u1ee9ng qu\u00e1 m\u1eabn: Ph\u00e1t ban \u1edf da, n\u1ed7i m\u00e8 \u0111ay, s\u1ed1t, ng\u1ee9a, ban \u0111\u1ecf, h\u1ed9i ch\u1ee9ng Stevens &#8211; Johnson.<\/p>\n<p>Gan: T\u0103ng tho\u00e1ng qua SGPT, SGOT v\u00e0 phosphatase ki\u1ec1m.<\/p>\n<p>Th\u1eadn: T\u0103ng tho\u00e1ng qua BUN hay Creatinin.<\/p>\n<p>Th\u1ea7n kinh trung \u01b0\u01a1ng: \u0110au \u0111\u1ea7u hay ch\u00f3ng m\u1eb7t.<\/p>\n<p>Huy\u1ebft h\u1ecdc: Gi\u1ea3m ti\u1ec3u c\u1ea7u, gi\u1ea3m b\u1ea1ch c\u1ea7u, t\u0103ng b\u1ea1ch c\u1ea7u \u01b0a eosin.<\/p>\n<p>C\u00e1c tri\u1ec7u ch\u1ee9ng kh\u00e1c: ng\u1ee9a b\u1ed9 ph\u1eadn sinh d\u1ee5c, vi\u00eam \u00e2m \u0111\u1ea1o, n\u1ea5m Candida.<\/p>\n<p><em>Th\u00f4ng b\u00e1o cho B\u00e1c s\u0129 nh\u1eefng t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n g\u1eb7p ph\u1ea3i khi s\u1eed d\u1ee5ng thu\u1ed1c.<\/em><\/p>\n<p><strong>4.7 H\u01b0\u1edbng d\u1eabn c\u00e1ch x\u1eed tr\u00ed ADR:<\/strong><\/p>\n<p>Ng\u1eebng s\u1eed d\u1ee5ng thu\u1ed1c. V\u1edbi c\u00e1c ph\u1ea3n \u1ee9ng b\u1ea5t l\u1ee3i nh\u1eb9, th\u01b0\u1eddng ch\u1ec9 c\u1ea7n ng\u1eebng thu\u1ed1c. Tr\u01b0\u1eddng h\u1ee3p m\u1eabn c\u1ea3m n\u1eb7ng ho\u1eb7c ph\u1ea3n \u1ee9ng d\u1ecb \u1ee9ng, c\u1ea7n ti\u1ebfn h\u00e0nh \u0111i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3 (gi\u1eef tho\u00e1ng kh\u00ed v\u00e0 d\u00f9ng epinephrin, th\u1edf oxygen, d\u00f9ng kh\u00e1ng histamin, corticoid&#8230;).<\/p>\n<p><strong>4.8 T\u01b0\u01a1ng t\u00e1c v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1c:<\/strong><\/p>\n<p>Probenecid l\u00e0m t\u0103ng n\u00f4ng \u0111\u1ed9 \u0111\u1ec9nh v\u00e0 AUC c\u1ee7a cefixim, gi\u1ea3m \u0111\u1ed9 thanh th\u1ea3i c\u1ee7a th\u1eadn v\u00e0 th\u1ec3 t\u00edch ph\u00e2n b\u1ed1 c\u1ee7a thu\u00f4c.<\/p>\n<p>C\u00e1c thu\u1ed1c ch\u1ed1ng \u0111\u00f4ng nh\u01b0 warfarin khi d\u00f9ng c\u00f9ng cefixim l\u00e0m t\u0103ng th\u1eddi gian prothrombin, c\u00f3 ho\u1eb7c kh\u00f4ng k\u00e8m theo ch\u1ea3y m\u00e1u.<\/p>\n<p>Carbamazepin u\u1ed1ng c\u00f9ng cefixim l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 carbamazepin trong huy\u1ebft t\u01b0\u01a1ng.<\/p>\n<p>Nifedipin khi u\u1ed1ng c\u00f9ng cefixim l\u00e0m t\u0103ng sinh kh\u1ea3 d\u1ee5ng c\u1ee7a cefixim bi\u1ec3u hi\u1ec7n b\u1eb1ng t\u0103ng n\u00f4ng \u0111\u1ed9 \u0111\u1ec9nh v\u00e0 AUC<\/p>\n<p><strong>4.9 Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed:<\/strong><\/p>\n<p>Ch\u1ec9 \u0111\u1ecbnh r\u1eeda d\u1ea1 d\u00e0y, ngo\u00e0i ra kh\u00f4ng c\u00f3 thu\u1ed1c gi\u1ea3i \u0111\u1ed9c \u0111\u1eb7c hi\u1ec7u. Vi\u1ec7c th\u1ea9m ph\u00e2n huy\u1ebft v\u00e0 th\u1ea9m ph\u00e2n m\u00e0ng b\u1ee5ng kh\u00f4ng lo\u1ea1i \u0111\u01b0\u1ee3c m\u1ed9t l\u01b0\u1ee3ng \u0111\u00e1ng k\u1ec3 kh\u1ecfi c\u01a1 th\u1ec3. C\u00e1c t\u00e1c d\u1ee5ng ngo\u1ea1i \u00fd tr\u00ean m\u1ed9t nh\u00f3m nh\u1ecf ng\u01b0\u1eddi t\u00ecnh nguy\u1ec7n d\u00f9ng thu\u1ed1c v\u1edbi li\u1ec1u cao \u0111\u1ebfn 2 g Cefixim kh\u00f4ng kh\u00e1c g\u00ec v\u1edbi c\u00e1c t\u00e1c d\u1ee5ng ngo\u1ea1i \u00fd th\u01b0\u1eddng g\u1eb7p \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n d\u00f9ng v\u1edbi li\u1ec1u th\u00f4ng th\u01b0\u1eddng.<\/p>\n<p><script src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-5528370293090692\" async=\"\" crossorigin=\"anonymous\"><\/script><ins class=\"adsbygoogle\" style=\"display: block; text-align: center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-5528370293090692\" data-ad-slot=\"8909623906\"><\/ins><script> (adsbygoogle = window.adsbygoogle || []).push({}); <\/script><\/p>\n<p><strong>5. C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c :<\/strong><\/p>\n<p><strong>5.1. D\u01b0\u1ee3c l\u1ef1c h\u1ecdc:<\/strong><\/p>\n<p>Cefixim l\u00e0 kh\u00e1ng sinh thu\u1ed9c nh\u00f3m Cephalosporin th\u1ebf h\u1ec7 3. T\u00e1c d\u1ee5ng di\u1ec7t khu\u1ea9n do \u1ee9c ch\u1ebf s\u1ef1 t\u1ed5ng h\u1ee3p th\u00e0nh t\u1ebf b\u00e0o.<\/p>\n<p>Cefixim c\u00f3 \u0111\u1ed9 \u1ed5n \u0111\u1ecbnh cao v\u1edbi s\u1ef1 c\u00f3 m\u1eb7t c\u1ee7a c\u00e1c enzym beta \u2014 lactamase.<\/p>\n<p><strong><em>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng: <\/em><\/strong><\/p>\n<p>Cefixime l\u00e0 m\u1ed9t kh\u00e1nh sinh cephalosporin th\u1ebf h\u1ec7 3, \u0111\u01b0\u1ee3c d\u00f9ng theo \u0111\u01b0\u1eddng u\u1ed1ng. Thu\u1ed1c c\u00f3 t\u00e1c d\u1ee5ng di\u1ec7t khu\u1ea9n. C\u01a1 ch\u1ebf di\u1ec7t khu\u1ea9n c\u1ee7a cefixime t\u01b0\u01a1ng t\u1ef1 nh\u01b0 c\u1ee7a c\u00e1c cephalosporin kh\u00e1c: g\u1eafn v\u00e0o c\u00e1c protein \u0111\u00edch (protein g\u1eafn penicilin) g\u00e2y \u1ee9c ch\u1ebf qu\u00e1 tr\u00ecnh t\u1ed5ng h\u1ee3p mucopeptid \u1edf th\u00e0nh t\u1ebf b\u00e0o vi khu\u00e2n. C\u01a1 ch\u1ebf kh\u00e1ng cefixime c\u1ee7a vi khu\u1ea9n l\u00e0 gi\u1ea3m \u00e1i l\u1ef1c c\u1ee7a cefixime \u0111\u1ed1i v\u1edbi protein \u0111\u00edch ho\u1eb7c gi\u1ea3m t\u00ednh th\u1ea5m c\u1ee7a m\u00e0ng t\u1ebf b\u00e0o vi khu\u1ea9n \u0111\u1ed1i v\u1edbi thu\u1ed1c.<\/p>\n<p>Cefixim c\u00f3 \u0111\u1ed9 b\u1ec1n v\u1eefng cao v\u1edbi s\u1ef1 th\u1ee7y ph\u00e2n c\u1ee7a beta-lactamase m\u00e3 h\u00f3a b\u1edfi gen n\u1eb1m tr\u00ean plasmid v\u00e0 chromosom. T\u00ednh b\u1ec1n v\u1eefng v\u1edbi beta-lactamase c\u1ee7a cefixime cao h\u01a1n cefaclor, cefoxitin, cefuroxime, cephalexin, cephradin.<\/p>\n<p><a href=\"https:\/\/www.youtube.com\/watch?v=0TIIfoiJFwA\"><strong>[XEM T\u1ea0I \u0110\u00c2Y]<\/strong><\/a><\/p>\n<p><strong>5.2. D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc:<\/strong><\/p>\n<p>H\u1ea5p thu kho\u1ea3ng 40% \u0111\u1ebfn 50% khi d\u00f9ng c\u00f9ng ho\u1eb7c kh\u00f4ng c\u00f9ng v\u1edbi th\u1ee9c \u0103n. Th\u1eddi gian \u0111\u1ea1t \u0111\u01b0\u1ee3c s\u1ef1 h\u1ea5p thu t\u1ed1i \u0111a l\u00e0 kho\u1ea3ng 0,8 gi\u1edd khi u\u1ed1ng trong b\u1eefa \u0103n.<\/p>\n<p>Kho\u1ea3ng 50% li\u1ec1u h\u1ea5p thu \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb nguy\u00ean v\u1eb9n qua n\u01b0\u1edbc ti\u1ec3u trong 24 gi\u1edd.<\/p>\n<p><strong>5.3 Gi\u1ea3i th\u00edch: <\/strong><\/p>\n<p>Ch\u01b0a c\u00f3 th\u00f4ng tin. \u0110ang c\u1eadp nh\u1eadt.<\/p>\n<p><strong>5.4 Thay th\u1ebf thu\u1ed1c : <\/strong><\/p>\n<p>Ch\u01b0a c\u00f3 th\u00f4ng tin. \u0110ang c\u1eadp nh\u1eadt.<\/p>\n<p><strong><em>*L\u01b0u \u00fd:<\/em><\/strong><\/p>\n<p><strong><em>C\u00e1c th\u00f4ng tin v\u1ec1 thu\u1ed1c tr\u00ean Pharmog.com ch\u1ec9 mang t\u00ednh ch\u1ea5t tham kh\u1ea3o &#8211; Khi d\u00f9ng thu\u1ed1c c\u1ea7n tuy\u1ec7t \u0111\u1ed1i tu\u00e2n theo theo h\u01b0\u1edbng d\u1eabn c\u1ee7a B\u00e1c s\u0129 <\/em><\/strong><\/p>\n<p><strong><em>Ch\u00fang t\u00f4i kh\u00f4ng ch\u1ecbu tr\u00e1ch nhi\u1ec7m v\u1ec1 b\u1ea5t c\u1ee9 h\u1eadu qu\u1ea3 n\u00e0o x\u1ea3y ra do t\u1ef1 \u00fd d\u00f9ng thu\u1ed1c d\u1ef1a theo c\u00e1c th\u00f4ng tin tr\u00ean Pharmog.com<\/em><\/strong><\/p>\n<p><script src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-5528370293090692\" async=\"\" crossorigin=\"anonymous\"><\/script><ins class=\"adsbygoogle\" style=\"display: block; text-align: center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-5528370293090692\" data-ad-slot=\"8909623906\"><\/ins><script> (adsbygoogle = window.adsbygoogle || []).push({}); <\/script><\/p>\n<p><strong>6. Ph\u1ea7n th\u00f4ng tin k\u00e8m theo c\u1ee7a thu\u1ed1c:<\/strong><\/p>\n<p><strong>6.1. Danh m\u1ee5c t\u00e1 d\u01b0\u1ee3c:<\/strong><\/p>\n<p>Hydroxy propyl cellulose (RT-LF), dibasic calcium phosphate anhydrous granular, aspartame, powdarome orange premium, (powder) colloidal silicon dioxide, crospovidone, starch, magnesium stearate, lake sunset yellow..<\/p>\n<p><strong>6.2. T\u01b0\u01a1ng k\u1ef5 :<\/strong><\/p>\n<p>Kh\u00f4ng \u00e1p d\u1ee5ng.<\/p>\n<p><strong>6.3. B\u1ea3o qu\u1ea3n: <\/strong><\/p>\n<p>N\u01a1i kh\u00f4, tr\u00e1nh \u00e1nh s\u00e1ng, nhi\u1ec7t \u0111\u1ed9 d\u01b0\u1edbi 30\u00b0C.<\/p>\n<p><strong>6.4. Th\u00f4ng tin kh\u00e1c :<\/strong><\/p>\n<p>Kh\u00f4ng c\u00f3.<\/p>\n<p><strong>6.5 T\u00e0i li\u1ec7u tham kh\u1ea3o:<\/strong><\/p>\n<p>D\u01b0\u1ee3c Th\u01b0 Qu\u1ed1c Gia Vi\u1ec7t Nam.<\/p>\n<p>HDSD Thu\u1ed1c Ceftacef<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>1. T\u00ean ho\u1ea1t ch\u1ea5t v\u00e0 bi\u1ec7t d\u01b0\u1ee3c: Ho\u1ea1t ch\u1ea5t : Cefixime Ph\u00e2n lo\u1ea1i: Thu\u1ed1c kh\u00e1ng sinh cephalosporin th\u1ebf h\u1ec7 3. Nh\u00f3m ph\u00e1p l\u00fd: Thu\u1ed1c k\u00ea \u0111\u01a1n ETC \u2013 (Ethical drugs, prescription drugs, Prescription only medicine) M\u00e3 ATC (Anatomical Therapeutic Chemical): J01DD08. Bi\u1ec7t d\u01b0\u1ee3c g\u1ed1c: Bi\u1ec7t d\u01b0\u1ee3c: Egofixim H\u00e3ng s\u1ea3n xu\u1ea5t : C\u00f4ng ty c\u1ed5 ph\u1ea7n [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":16445,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[419],"tags":[571],"class_list":["post-16444","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-biet-duoc","tag-cefixime"],"_links":{"self":[{"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/posts\/16444","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/comments?post=16444"}],"version-history":[{"count":3,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/posts\/16444\/revisions"}],"predecessor-version":[{"id":51010,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/posts\/16444\/revisions\/51010"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/media\/16445"}],"wp:attachment":[{"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/media?parent=16444"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/categories?post=16444"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/tags?post=16444"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}