{"id":15141,"date":"2019-10-27T11:31:23","date_gmt":"2019-10-27T04:31:23","guid":{"rendered":"https:\/\/pharmog.com\/wp\/?p=15141"},"modified":"2025-01-09T08:31:14","modified_gmt":"2025-01-09T01:31:14","slug":"captopril-taguar","status":"publish","type":"post","link":"https:\/\/pharmog.com\/wp\/captopril-taguar\/","title":{"rendered":"Captopril &#8211; Taguar"},"content":{"rendered":"<p><strong>1. T\u00ean ho\u1ea1t ch\u1ea5t v\u00e0 bi\u1ec7t d\u01b0\u1ee3c: <\/strong><\/p>\n<p><strong><em>Ho\u1ea1t ch\u1ea5t :<\/em> <a href=\"https:\/\/pharmog.com\/wp\/captopril\/\">Captopril<\/a><\/strong><\/p>\n<p><strong><em>Ph\u00e2n lo\u1ea1i: <\/em><\/strong><em>Thu\u1ed1c \u1ee9c ch\u1ebf men chuy\u1ec3n. Thu\u1ed1c \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p.<\/em><\/p>\n<p><strong><em>Nh\u00f3m<\/em><\/strong> <strong><em>ph\u00e1p l\u00fd: <\/em><\/strong><em>Thu\u1ed1c k\u00ea \u0111\u01a1n ETC \u2013 (Ethical drugs, prescription drugs, Prescription only medicine)<\/em><\/p>\n<p><strong><em>M\u00e3 ATC<\/em><\/strong> (Anatomical Therapeutic Chemical): C09AA01.<\/p>\n<p><strong><em>Bi\u1ec7t d\u01b0\u1ee3c g\u1ed1c:<\/em><\/strong><\/p>\n<p><strong><em>Bi\u1ec7t d\u01b0\u1ee3c:<\/em><\/strong> TAGUAR<\/p>\n<p><strong><em>H\u00e3ng s\u1ea3n xu\u1ea5t <\/em><\/strong>: Aurobindo Pharma Ltd..<\/p>\n<p><script src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-5528370293090692\" async=\"\" crossorigin=\"anonymous\"><\/script><ins class=\"adsbygoogle\" style=\"display: block; text-align: center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-5528370293090692\" data-ad-slot=\"8909623906\"><\/ins><script> (adsbygoogle = window.adsbygoogle || []).push({}); <\/script><\/p>\n<p><strong>2. D\u1ea1ng b\u00e0o ch\u1ebf &#8211; H\u00e0m l\u01b0\u1ee3ng: <\/strong><\/p>\n<p><strong><em>D\u1ea1ng thu\u1ed1c v\u00e0 h\u00e0m l\u01b0\u1ee3ng<\/em><\/strong><\/p>\n<p>Vi\u00ean n\u00e9n: 12,5 mg, 25 mg.<\/p>\n<p><strong><em>Thu\u1ed1c tham kh\u1ea3o:<\/em><\/strong><\/p>\n<table>\n<tbody>\n<tr>\n<td colspan=\"2\"><strong><em>TAGUAR 25mg<\/em><\/strong><\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\"><em>M\u1ed7i vi\u00ean n\u00e9n bao phim c\u00f3 ch\u1ee9a:<\/em><\/td>\n<td><\/td>\n<\/tr>\n<tr>\n<td>Captopril<\/td>\n<td>&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.<\/td>\n<td>25 mg<\/td>\n<\/tr>\n<tr>\n<td>T\u00e1 d\u01b0\u1ee3c<\/td>\n<td>&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.<\/td>\n<td>v\u1eeba \u0111\u1ee7 (Xem m\u1ee5c 6.1)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><img loading=\"lazy\" decoding=\"async\" width=\"749\" height=\"284\" class=\"wp-image-15142\" src=\"https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2019\/10\/word-image-31.png\" srcset=\"https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2019\/10\/word-image-31.png 749w, https:\/\/pharmog.com\/wp\/wp-content\/uploads\/2019\/10\/word-image-31-300x114.png 300w\" sizes=\"auto, (max-width: 749px) 100vw, 749px\" \/><\/p>\n<p><strong>3. Video by Pharmog:<\/strong><\/p>\n<p><strong>[VIDEO D\u01af\u1ee2C L\u00dd]<\/strong><\/p>\n<div class=\"ast-oembed-container \" style=\"height: 100%;\"><iframe loading=\"lazy\" title=\"[Pharmog SS1 - T\u1eadp 11] - D\u01b0\u1ee3c l\u00fd v\u1ec1 thu\u1ed1c \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/F1Pl4DO5flA?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe><\/div>\n<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<\/p>\n<p>\u25ba K\u1ecbch B\u1ea3n: PharmogTeam<\/p>\n<p>\u25ba Youtube: https:\/\/www.youtube.com\/c\/pharmog<\/p>\n<p>\u25ba Facebook: https:\/\/www.facebook.com\/pharmog\/<\/p>\n<p>\u25ba Group : H\u1ed9i nh\u1eefng ng\u01b0\u1eddi m\u00ea d\u01b0\u1ee3c l\u00fd<\/p>\n<p>\u25ba Instagram : https:\/\/www.instagram.com\/pharmogvn\/<\/p>\n<p>\u25ba Website: pharmog.com<\/p>\n<p><strong>4. \u1ee8ng d\u1ee5ng l\u00e2m s\u00e0ng: <\/strong><\/p>\n<p><strong>4.1. Ch\u1ec9 \u0111\u1ecbnh:<\/strong><\/p>\n<p>T\u0103ng huy\u1ebft \u00e1p.<\/p>\n<p>Suy tim sung huy\u1ebft.<\/p>\n<p>Nh\u1ed3i m\u00e1u c\u01a1 tim trong 24 gi\u1edd \u0111\u1ea7u (\u1edf ng\u01b0\u1eddi b\u1ec7nh \u0111\u00e3 c\u00f3 huy\u1ebft \u0111\u1ed9ng \u1ed5n \u0111\u1ecbnh).<\/p>\n<p>R\u1ed1i lo\u1ea1n ch\u1ee9c n\u0103ng th\u1ea5t tr\u00e1i sau nh\u1ed3i m\u00e1u c\u01a1 tim c\u1ea5p.<\/p>\n<p>B\u1ec7nh th\u1eadn do \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng<\/p>\n<p><strong>4.2. Li\u1ec1u d\u00f9ng &#8211; C\u00e1ch d\u00f9ng:<\/strong><\/p>\n<p><strong><em>C\u00e1ch d\u00f9ng<\/em><\/strong> : D\u00f9ng u\u1ed1ng.<\/p>\n<p>U\u1ed1ng captopril tr\u01b0\u1edbc \u0103n 1 gi\u1edd ho\u1eb7c 2 gi\u1edd sau b\u1eefa \u0103n<\/p>\n<p><strong><em>Li\u1ec1u d\u00f9ng:<\/em><\/strong><\/p>\n<p>T\u0103ng huy\u1ebft \u00e1p: li\u1ec1u th\u01b0\u1eddng d\u00f9ng 25mg (1 vi\u00ean)\/l\u1ea7n, 2-3 l\u1ea7n\/ng\u00e0y. N\u1ebfu huy\u1ebft \u00e1p kh\u00f4ng ki\u1ec3m so\u00e1t sau 1-2 tu\u1ea7n, c\u00f3 th\u1ec3 t\u0103ng li\u1ec1u t\u1edbi 50mg\/l\u1ea7n, ng\u00e0y 2-3 l\u1ea7n.<\/p>\n<p>Suy tim: n\u00ean d\u00f9ng ph\u1ed1i h\u1ee3p v\u1edbi thu\u1ed1c l\u1ee3i ti\u1ec3u. Li\u1ec1u th\u01b0\u1eddng d\u00f9ng 6.25 &#8211; 25mg \/l\u1ea7n, 3 l\u1ea7n\/ng\u00e0y<\/p>\n<p>B\u1ec7nh th\u1eadn do \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng: 25mg\/l\u1ea7n, 3 l\u1ea7n m\u1ed7i ng\u00e0y d\u00f9ng l\u00e2u d\u00e0i.<\/p>\n<p><strong>4.3. Ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh:<\/strong><\/p>\n<p>M\u1eabn c\u1ea3m v\u1edbi thu\u1ed1c ho\u1eb7c c\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf ACE.<\/p>\n<p>Ti\u1ec1n s\u1eed ph\u00f9 m\u1ea1ch.<\/p>\n<p>Sau nh\u1ed3i m\u00e1u c\u01a1 tim (n\u1ebfu huy\u1ebft \u0111\u1ed9ng kh\u00f4ng \u1ed5n \u0111\u1ecbnh).<\/p>\n<p>H\u1eb9p \u0111\u1ed9ng m\u1ea1ch th\u1eadn 2 b\u00ean ho\u1eb7c h\u1eb9p \u0111\u1ed9ng m\u1ea1ch th\u1eadn \u1edf th\u1eadn \u0111\u01a1n \u0111\u1ed9c.<\/p>\n<p>H\u1eb9p \u0111\u1ed9ng m\u1ea1ch ch\u1ee7 ho\u1eb7c h\u1eb9p van 2 l\u00e1.<\/p>\n<p>B\u1ec7nh c\u01a1 tim t\u1eafc ngh\u1ebdn n\u1eb7ng.<\/p>\n<p><strong>4.4 Th\u1eadn tr\u1ecdng:<\/strong><\/p>\n<p>Thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y gi\u1ea3m b\u1ea1ch c\u1ea7u trung t\u00ednh, \u0111\u1eb7c bi\u1ec7t tr\u00ean ng\u01b0\u1eddi b\u1ec7nh th\u1eadn, trong 3 &#8211; 12 tu\u1ea7n \u0111i\u1ec1u tr\u1ecb \u0111\u1ea7u ti\u00ean. Nguy c\u01a1 gi\u1ea3m b\u1ea1ch c\u1ea7u ph\u1ee5 thu\u1ed9c v\u00e0o m\u1ee9c \u0111\u1ed9 suy th\u1eadn v\u00e0 c\u00e1c b\u1ec7nh colagen m\u1ea1ch m\u00e1u k\u00e8m theo (lupus ban \u0111\u1ecf h\u1ec7 th\u1ed1ng&#8230;). C\u1ea7n ki\u1ec3m tra \u0111\u1ecbnh k\u1ef3 b\u1ea1ch c\u1ea7u trong th\u1eddi gian \u0111i\u1ec1u tr\u1ecb.<\/p>\n<p>C\u00f3 th\u1ec3 g\u00e2y protein ni\u1ec7u \u1edf b\u1ec7nh nh\u00e2n d\u00f9ng captopril, ph\u1ea7n l\u1edbn \u1edf ng\u01b0\u1eddi c\u00f3 b\u1ec7nh th\u1eadn t\u1eeb tr\u01b0\u1edbc ho\u1eb7c \u0111\u00e3 d\u00f9ng captopril v\u1edbi li\u1ec1u t\u01b0\u01a1ng \u0111\u1ed1i cao (&gt;150 mg\/ng\u00e0y) ho\u1eb7c c\u00f3 c\u1ea3 2 y\u1ebfu t\u1ed1 tr\u00ean. Trong nhi\u1ec1u tr\u01b0\u1eddng h\u1ee3p, protein ni\u1ec7u gi\u1ea3m d\u1ea7n v\u00e0 h\u1ebft trong 6 th\u00e1ng, d\u00f9 c\u00f3 d\u00f9ng thu\u1ed1c hay kh\u00f4ng. C\u00f3 th\u1ec3 g\u00e2y h\u1ed9i ch\u1ee9ng th\u1eadn h\u01b0, v\u00ec v\u1eady n\u00ean ki\u1ec3m tra ch\u1ee9c n\u0103ng th\u1eadn (creatinin huy\u1ebft v\u00e0 BUN) tr\u01b0\u1edbc v\u00e0 1 tu\u1ea7n sau khi \u0111i\u1ec1u tr\u1ecb captopril cho ng\u01b0\u1eddi b\u1ecb suy tim sung huy\u1ebft.<\/p>\n<p>Captopril c\u00f3 th\u1ec3 g\u00e2y t\u0103ng nh\u1eb9 kali huy\u1ebft, v\u00ec v\u1eady tr\u00e1nh k\u1ebft h\u1ee3p v\u1edbi c\u00e1c thu\u1ed1c l\u1ee3i ti\u1ec3u gi\u1eef kali (spironolacton, triamteren&#8230;). C\u1ea7n th\u1eadn tr\u1ecdng khi d\u00f9ng c\u00e1c mu\u1ed1i c\u00f3 ch\u1ee9a kali v\u00e0 n\u00ean ki\u1ec3m tra c\u00e2n b\u1eb1ng \u0111i\u1ec7n gi\u1ea3i \u0111\u1ecbnh k\u1ef3.<\/p>\n<p>\u1eda ng\u01b0\u1eddi b\u1ec7nh t\u0103ng ho\u1ea1t \u0111\u1ed9 renin m\u1ea1nh, thi\u1ebfu mu\u1ed1i ho\u1eb7c gi\u1ea3m kh\u1ed1i l\u01b0\u1ee3ng tu\u1ea7n ho\u00e0n c\u00f3 th\u1ec3 x\u1ea3y ra h\u1ea1 huy\u1ebft \u00e1p n\u1eb7ng th\u1ebf \u0111\u1ee9ng sau li\u1ec1u d\u00f9ng captopril \u0111\u1ea7u ti\u00ean, c\u1ea7n ti\u00eam truy\u1ec1n t\u0129nh m\u1ea1ch dung d\u1ecbch natri clorid 0,9%, kh\u00f4ng c\u1ea7n ng\u1eebng thu\u1ed1c. N\u1ebfu li\u1ec1u ban \u0111\u1ea7u th\u1ea5p (6,25 mg ho\u1eb7c 12,5 mg), th\u1eddi gian h\u1ea1 huy\u1ebft \u00e1p n\u1eb7ng s\u1ebd gi\u1ea3m.<\/p>\n<p>Nguy c\u01a1 t\u0103ng m\u1ea1nh c\u00e1c ph\u1ea3n \u1ee9ng ph\u1ea3n v\u1ec7 khi s\u1eed d\u1ee5ng \u0111\u1ed3ng th\u1eddi c\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf ACE v\u00e0 m\u00e0ng th\u1ea5m t\u00e1ch c\u00f3 t\u00ednh th\u1ea5m cao, l\u1ecdc m\u00e1u. Captopril c\u0169ng g\u00e2y ph\u1ea3n \u1ee9ng d\u01b0\u01a1ng t\u00ednh gi\u1ea3 khi x\u00e9t nghi\u1ec7m aceton trong n\u01b0\u1edbc ti\u1ec3u<\/p>\n<p><strong>T\u00e1c \u0111\u1ed9ng c\u1ee7a thu\u1ed1c tr\u00ean ng\u01b0\u1eddi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/strong><\/p>\n<p>C\u1ea7n th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng cho c\u00e1c \u0111\u1ed1i t\u01b0\u1ee3ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/p>\n<p><script src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-5528370293090692\" async=\"\" crossorigin=\"anonymous\"><\/script><ins class=\"adsbygoogle\" style=\"display: block; text-align: center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-5528370293090692\" data-ad-slot=\"8909623906\"><\/ins><script> (adsbygoogle = window.adsbygoogle || []).push({}); <\/script><\/p>\n<p><strong>4.5 S\u1eed d\u1ee5ng cho ph\u1ee5 n\u1eef c\u00f3 thai v\u00e0 cho con b\u00fa:<\/strong><\/p>\n<p><em>X\u1ebfp h\u1ea1ng c\u1ea3nh b\u00e1o<\/em><\/p>\n<p>AU TGA pregnancy category: D<\/p>\n<p>US FDA pregnancy category: D<\/p>\n<p><em>Th\u1eddi k\u1ef3 mang thai:<\/em><\/p>\n<p>S\u1eed d\u1ee5ng captopril ho\u1eb7c c\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf ACE kh\u00e1c trong 3 th\u00e1ng gi\u1eefa v\u00e0 3 th\u00e1ng cu\u1ed1i c\u1ee7a thai k\u1ef3 c\u00f3 th\u1ec3 g\u00e2y th\u01b0\u01a1ng t\u1ed5n thai nhi hay tr\u1ebb s\u01a1 sinh (h\u1ea1 huy\u1ebft \u00e1p, gi\u1ea3m s\u1ea3n x\u01b0\u01a1ng s\u1ecd, suy th\u1eadn, t\u1eed vong). \u00cdt n\u01b0\u1edbc \u1ed1i, d\u1ecb d\u1ea1ng s\u1ecd m\u1eb7t, gi\u1ea3m s\u1ea3n ph\u1ed5i, sinh non, thai gi\u00e0 th\u00e1ng, c\u00f2n \u1ed1ng \u0111\u1ed9ng m\u1ea1ch c\u00f3 th\u1ec3 x\u1ea3y ra. V\u00ec v\u1eady, kh\u00f4ng \u0111\u01b0\u1ee3c d\u00f9ng captopril trong th\u1eddi k\u1ef3 mang thai<\/p>\n<p><em>Th\u1eddi k\u1ef3 cho con b\u00fa:<\/em><\/p>\n<p>Captopril b\u00e0i ti\u1ebft v\u00e0o s\u1eefa m\u1eb9 (kho\u1ea3ng 1%), g\u00e2y nhi\u1ec1u t\u00e1c d\u1ee5ng c\u00f3 h\u1ea1i cho tr\u1ebb b\u00fa s\u1eefa m\u1eb9, v\u00ec v\u1eady c\u1ea7n c\u00e2n nh\u1eafc ng\u1eebng cho con b\u00fa hay ng\u1eebng thu\u1ed1c, ph\u1ea3i t\u00ednh \u0111\u1ebfn t\u1ea7m quan tr\u1ecdng c\u1ee7a thu\u1ed1c \u0111\u1ed1i v\u1edbi m\u1eb9<\/p>\n<p><strong>4.6 T\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n (ADR):<\/strong><\/p>\n<p>ADR ch\u1ee7 y\u1ebfu l\u00e0 ngo\u1ea1i ban v\u00e0 m\u1ea5t v\u1ecb gi\u00e1c. C\u00e1c t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n th\u01b0\u1eddng ph\u1ee5 thu\u1ed9c v\u00e0o li\u1ec1u d\u00f9ng v\u00e0 li\u00ean quan \u0111\u1ebfn nh\u1eefng y\u1ebfu t\u1ed1 bi\u1ebfn ch\u1ee9ng nh\u01b0 suy th\u1eadn, b\u1ec7nh m\u00f4 li\u00ean k\u1ebft \u1edf m\u1ea1ch m\u00e1u.<\/p>\n<p><em>Th\u01b0\u1eddng g\u1eb7p, ADR &gt;1\/100 <\/em>To\u00e0n th\u00e2n: \u0110au \u0111\u1ea7u, ch\u00f3ng m\u1eb7t.<\/p>\n<p>Da: Ngo\u1ea1i ban, ng\u1ee9a.<\/p>\n<p>Ti\u00eau h\u00f3a: M\u1ea5t v\u1ecb gi\u00e1c.<\/p>\n<p>M\u00e1u: Gi\u1ea3m b\u1ea1ch c\u1ea7u trung t\u00ednh.<\/p>\n<p>H\u00f4 h\u1ea5p: Ho.<\/p>\n<p><em>\u00cdt g\u1eb7p, 1\/100 &gt;ADR &gt;1\/1 000<\/em><\/p>\n<p>Tu\u1ea7n ho\u00e0n: H\u1ea1 huy\u1ebft \u00e1p m\u1ea1nh, tim \u0111\u1eadp nhanh, \u0111au ng\u1ef1c.<\/p>\n<p>Ti\u00eau h\u00f3a: Thay \u0111\u1ed5i v\u1ecb gi\u00e1c, bu\u1ed3n n\u00f4n, n\u00f4n, vi\u00eam d\u1ea1 d\u00e0y, \u0111au b\u1ee5ng. Ti\u1ebft ni\u1ec7u: Protein ni\u1ec7u.<\/p>\n<p><em>Hi\u1ebfm g\u1eb7p, ADR &lt;1\/1 000<\/em><\/p>\n<p>To\u00e0n th\u00e2n: Suy nh\u01b0\u1ee3c, m\u00e0y \u0111ay, \u0111au c\u01a1, s\u1ed1t, s\u00fat c\u00e2n.<\/p>\n<p>Tu\u1ea7n ho\u00e0n: Ng\u1eebng tim, thi\u1ec3u n\u0103ng m\u1ea1ch n\u00e3o, lo\u1ea1n nh\u1ecbp, h\u1ea1 huy\u1ebft \u00e1p th\u1ec3 \u0111\u1ee9ng, ng\u1ea5t, vi\u00eam m\u1ea1ch.<\/p>\n<p>N\u1ed9i ti\u1ebft: V\u00fa to nam gi\u1edbi.<\/p>\n<p>Da: Ph\u00f9 m\u1ea1ch, ph\u1ed3ng m\u00f4i, ph\u1ed3ng l\u01b0\u1ee1i. M\u1eabn c\u1ea3m \u00e1nh s\u00e1ng, ph\u00e1t ban ki\u1ec3u pemphigus, h\u1ed3ng ban \u0111a d\u1ea1ng, h\u1ed9i ch\u1ee9ng Stevens-Johnson, vi\u00eam da tr\u00f3c v\u1ea3y.<\/p>\n<p>Ti\u00eau h\u00f3a: Vi\u00eam t\u1ee5y, vi\u00eam l\u01b0\u1ee1i, kh\u00f3 ti\u00eau.<\/p>\n<p>Gan: V\u00e0ng da, vi\u00eam gan \u0111\u00f4i khi ho\u1ea1i t\u1eed, \u1ee9 m\u1eadt.<\/p>\n<p>H\u00f4 h\u1ea5p: Co th\u1eaft ph\u1ebf qu\u1ea3n, vi\u00eam ph\u1ed5i, t\u0103ng b\u1ea1ch c\u1ea7u \u01b0a eosin, vi\u00eam m\u0169i.<\/p>\n<p>Th\u1ea7n kinh &#8211; t\u00e2m th\u1ea7n: M\u1ea5t \u0111i\u1ec1u h\u00f2a, co gi\u1eadt, lo l\u1eafng, tr\u1ea7m c\u1ea3m, bu\u1ed3n ng\u1ee7.<\/p>\n<p>Ti\u1ebft ni\u1ec7u: H\u1ed9i ch\u1ee9ng th\u1eadn h\u01b0, gi\u1ea3m ch\u1ee9c n\u0103ng th\u1eadn, t\u0103ng kali m\u00e1u, h\u1ea1 natri m\u00e1u<\/p>\n<p><em>Th\u00f4ng b\u00e1o cho B\u00e1c s\u0129 nh\u1eefng t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n g\u1eb7p ph\u1ea3i khi s\u1eed d\u1ee5ng thu\u1ed1c.<\/em><\/p>\n<p><strong>4.7 H\u01b0\u1edbng d\u1eabn c\u00e1ch x\u1eed tr\u00ed ADR:<\/strong><\/p>\n<p>T\u0103ng creatinin v\u00e0 ur\u00ea huy\u1ebft thanh c\u00f3 th\u1ec3 h\u1ed3i ph\u1ee5c khi ng\u1eebng thu\u1ed1c, tuy nhi\u00ean c\u1ea7n th\u1eadn tr\u1ecdng, \u0111\u1eb7c bi\u1ec7t \u1edf ng\u01b0\u1eddi suy th\u1eadn c\u00f3 h\u1eb9p \u0111\u1ed9ng m\u1ea1ch th\u1eadn m\u1ed9t b\u00ean. D\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c thu\u1ed1c l\u1ee3i ti\u1ec3u c\u0169ng c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nh\u1ea5t th\u1eddi creatinin v\u00e0 ur\u00ea huy\u1ebft thanh.<\/p>\n<p>Ngo\u1ea1i ban c\u00f3 d\u00e1t s\u1ea7n, ng\u1ee9a, m\u00e0y \u0111ay th\u01b0\u1eddng c\u00f3 th\u1ec3 x\u1ea3y ra khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb, song c\u00f3 th\u1ec3 m\u1ea5t \u0111i khi ti\u1ebfp t\u1ee5c \u0111i\u1ec1u tr\u1ecb v\u1edbi c\u00f9ng li\u1ec1u l\u01b0\u1ee3ng. Thay \u0111\u1ed5i v\u1ecb gi\u00e1c do d\u00f9ng thu\u1ed1c th\u01b0\u1eddng m\u1ea5t \u0111i trong v\u00f2ng 2 &#8211; 3 th\u00e1ng \u0111i\u1ec1u tr\u1ecb.<\/p>\n<p>\u1eda ng\u01b0\u1eddi b\u1ec7nh c\u00f3 h\u1ec7 th\u1ed1ng renin t\u0103ng ho\u1ea1t h\u00f3a c\u00f3 th\u1ec3 x\u1ea3y ra h\u1ea1 huy\u1ebft \u00e1p n\u1eb7ng trong nh\u1eefng gi\u1edd \u0111\u1ea7u s\u1eed d\u1ee5ng captopril, c\u1ea7n ti\u00eam truy\u1ec1n t\u0129nh m\u1ea1ch dung d\u1ecbch natri clorid 0,9%.<\/p>\n<p>Thu\u1ed1c c\u00f3 th\u1ec3 g\u00e2y suy th\u1eadn c\u1ea5p, v\u00ec v\u1eady khi ki\u1ec3m tra ch\u1ee9c n\u0103ng th\u1eadn th\u1ea5y c\u00f3 nit\u01a1 huy\u1ebft ti\u1ebfn tri\u1ec3n ph\u1ea3i ng\u1eebng s\u1eed d\u1ee5ng captopril<\/p>\n<p><strong>4.8 T\u01b0\u01a1ng t\u00e1c v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1c:<\/strong><\/p>\n<p>Captopril c\u00f3 th\u1ec3 l\u00e0m t\u0103ng t\u00e1c d\u1ee5ng c\u1ee7a allopurinol, amifostin, cyclosporin, c\u00e1c thu\u1ed1c \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p, lithi khi d\u00f9ng \u0111\u1ed3ng th\u1eddi.<\/p>\n<p>D\u00f9ng \u0111\u1ed3ng th\u1eddi captopril v\u1edbi fusosemid, thu\u1ed1c ch\u1eb9n receptor angiotensin II, diazoxid, thu\u1ed1c \u1ee9c ch\u1ebf MAO, trimethoprim g\u00e2y ra t\u00e1c d\u1ee5ng hi\u1ec7p \u0111\u1ed3ng h\u1ea1 huy\u1ebft \u00e1p.<\/p>\n<p>Thu\u1ed1c ch\u1ed1ng vi\u00eam kh\u00f4ng steroid, thu\u1ed1c kh\u00e1ng acid, aprotinin, yohimbin l\u00e0m gi\u1ea3m t\u00e1c d\u1ee5ng c\u1ee7a captopril khi d\u00f9ng \u0111\u1ed3ng th\u1eddi<\/p>\n<p><strong>4.9 Qu\u00e1 li\u1ec1u v\u00e0 x\u1eed tr\u00ed:<\/strong><\/p>\n<p><em>Tri\u1ec7u ch\u1ee9ng:<\/em> S\u1ed1t, nh\u1ee9c \u0111\u1ea7u, h\u1ea1 huy\u1ebft \u00e1p.<\/p>\n<p><em>X\u1eed tr\u00ed:<\/em> \u0110i\u1ec1u tr\u1ecb ph\u00f9 m\u1ea1ch \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn l\u01b0\u1ee1i, thanh m\u00f4n ho\u1eb7c thanh qu\u1ea3n:<\/p>\n<p>Ng\u1eebng d\u00f9ng captopril, ti\u00eam adrenalin d\u01b0\u1edbi da, ti\u00eam t\u0129nh m\u1ea1ch diphenhydramin, ti\u00eam t\u0129nh m\u1ea1ch hydrocortison.<\/p>\n<p>Truy\u1ec1n t\u0129nh m\u1ea1ch dung d\u1ecbch natri clorid 0,9% \u0111\u1ec3 duy tr\u00ec huy\u1ebft \u00e1p; c\u00f3 th\u1ec3 lo\u1ea1i b\u1ecf captopril b\u1eb1ng th\u1ea5m ph\u00e2n m\u00e1u<\/p>\n<p><script src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-5528370293090692\" async=\"\" crossorigin=\"anonymous\"><\/script><ins class=\"adsbygoogle\" style=\"display: block; text-align: center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-5528370293090692\" data-ad-slot=\"8909623906\"><\/ins><script> (adsbygoogle = window.adsbygoogle || []).push({}); <\/script><\/p>\n<p><strong>5. C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng c\u1ee7a thu\u1ed1c :<\/strong><\/p>\n<p><strong>5.1. D\u01b0\u1ee3c l\u1ef1c h\u1ecdc:<\/strong><\/p>\n<p>Captopril l\u00e0 m\u1ed9t ch\u1ea5t \u1ee9c ch\u1ebf men chuy\u1ec3n angiotensin: ng\u0103n angiotensin I chuy\u1ec3n th\u00e0nh angiotensin II, l\u00e0m gi\u1ea3m n\u1ed3ng \u0111\u1ed9 angiotensin II, l\u00e0m gi\u1ea3m co m\u1ea1ch, gi\u1ea3m ti\u1ebft aldosteron n\u00ean t\u0103ng th\u1ea3i natri v\u00e0 n\u01b0\u1edbc.<\/p>\n<p><strong><em>C\u01a1 ch\u1ebf t\u00e1c d\u1ee5ng: <\/em><\/strong><\/p>\n<p>Captopril l\u00e0 m\u1ed9t ch\u1ea5t \u1ee9c ch\u1ebf men chuy\u1ec3n d\u1ea1ng angiotensin, d\u00f9ng \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p v\u00e0 suy tim. T\u00e1c d\u1ee5ng h\u1ea1 huy\u1ebft \u00e1p c\u1ee7a thu\u1ed1c li\u00ean quan \u0111\u1ebfn \u1ee9c ch\u1ebf h\u1ec7 renin-angiotensin-aldosteron. Angiotensin I l\u00e0 m\u1ed9t decapeptid kh\u00f4ng c\u00f3 ho\u1ea1t t\u00ednh. Nh\u1edd s\u1ef1 x\u00fac t\u00e1c c\u1ee7a men chuy\u1ec3n d\u1ea1ng (ACE), angiotensin I chuy\u1ec3n th\u00e0nh angiotensin II c\u00f3 t\u00e1c d\u1ee5ng co m\u1ea1ch r\u1ea5t m\u1ea1nh. Angiotensin II k\u00edch th\u00edch v\u1ecf th\u01b0\u1ee3ng th\u1eadn ti\u1ebft aldosteron, c\u00f3 t\u00e1c d\u1ee5ng gi\u1eef natri v\u00e0 n\u01b0\u1edbc.<\/p>\n<p><a href=\"https:\/\/www.youtube.com\/watch?v=F1Pl4DO5flA\"><strong>[XEM T\u1ea0I \u0110\u00c2Y]<\/strong><\/a><\/p>\n<p><strong>5.2. D\u01b0\u1ee3c \u0111\u1ed9ng h\u1ecdc:<\/strong><\/p>\n<p>H\u1ea5p thu: \u1eda ng\u01b0\u1eddi kh\u1ecfe m\u1ea1nh ho\u1eb7c t\u0103ng huy\u1ebft \u00e1p, khi u\u1ed1ng m\u1ed9t li\u1ec1u captopril l\u00fac \u0111\u00f3i, kho\u1ea3ng 60 &#8211; 75% li\u1ec1u \u0111\u01b0\u1ee3c h\u1ea5p thu nhanh qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a. Th\u1ee9c \u0103n l\u00e0m h\u1ea5p thu ch\u1eadm t\u1edbi 25 &#8211; 40% nh\u01b0ng kh\u00f4ng \u1ea3nh h\u01b0\u1edfng t\u1edbi t\u00e1c d\u1ee5ng. Sau khi u\u1ed1ng 1 li\u1ec1u \u0111\u01a1n 100 mg captopril l\u00fac \u0111\u00f3i, n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trung b\u00ecnh trong m\u00e1u l\u00e0 800 nanogam\/ml, \u0111\u1ea1t \u0111\u01b0\u1ee3c trong v\u00f2ng 1 gi\u1edd.<\/p>\n<p>Ph\u00e2n b\u1ed1: Nghi\u00ean c\u1ee9u tr\u00ean \u0111\u1ed9ng v\u1eadt cho th\u1ea5y captopril ph\u00e2n b\u1ed1 v\u00e0o h\u1ea7u h\u1ebft c\u00e1c m\u00f4 c\u01a1 th\u1ec3, tr\u00ean h\u1ec7 th\u1ea7n kinh trung \u01b0\u01a1ng. Captopril qua nhau thai v\u00e0 v\u00e0o s\u1eefa m\u1eb9 v\u1edbi n\u1ed3ng \u0111\u1ed9 kho\u1ea3ng 1% n\u1ed3ng \u0111\u1ed9 thu\u1ed1c trong m\u00e1u m\u1eb9. Kho\u1ea3ng 25 &#8211; 30% captopril g\u1eafn v\u00e0o protein huy\u1ebft t\u01b0\u01a1ng, ch\u1ee7 y\u1ebfu l\u00e0 albumin.<\/p>\n<p>Th\u1ea3i tr\u1eeb: N\u1eeda \u0111\u1eddi th\u1ea3i tr\u1eeb captopril kh\u00f4ng chuy\u1ec3n h\u00f3a d\u01b0\u1edbi 2 gi\u1edd \u1edf ng\u01b0\u1eddi b\u1ec7nh c\u00f3 ch\u1ee9c n\u0103ng th\u1eadn b\u00ecnh th\u01b0\u1eddng. N\u1eeda \u0111\u1eddi th\u1ea3i tr\u1eeb c\u1ee7a captopril c\u00f9ng ch\u1ea5t chuy\u1ec3n h\u00f3a t\u01b0\u01a1ng quan v\u1edbi thanh th\u1ea3i creatinin v\u00e0 t\u0103ng t\u1edbi kho\u1ea3ng 20 &#8211; 40 gi\u1edd \u1edf ng\u01b0\u1eddi b\u1ec7nh c\u00f3 thanh th\u1ea3i creatinin d\u01b0\u1edbi 20 ml\/ph\u00fat v\u00e0 t\u1edbi 6,5 ng\u00e0y \u1edf ng\u01b0\u1eddi b\u1ec7nh v\u00f4 ni\u1ec7u.<\/p>\n<p>Kho\u1ea3ng m\u1ed9t n\u1eeda li\u1ec1u thu\u1ed1c h\u1ea5p thu \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a nhanh, ch\u1ee7 y\u1ebfu th\u00e0nh captopril-cystein disulfid v\u00e0 dimercaptopril disulfid. Thu\u1ed1c c\u00f3 th\u1ec3 chuy\u1ec3n h\u00f3a m\u1ea1nh h\u01a1n \u1edf ng\u01b0\u1eddi c\u00f3 ch\u1ee9c n\u0103ng th\u1eadn b\u1ecb t\u1ed5n th\u01b0\u01a1ng so v\u1edbi ng\u01b0\u1eddi c\u00f3 ch\u1ee9c n\u0103ng th\u1eadn b\u00ecnh th\u01b0\u1eddng.<\/p>\n<p>Captopril v\u00e0 ch\u1ea5t chuy\u1ec3n h\u00f3a b\u00e0i ti\u1ebft v\u00e0o n\u01b0\u1edbc ti\u1ec3u. Th\u1eadn b\u00e0i ti\u1ebft captopril kh\u00f4ng chuy\u1ec3n h\u00f3a ch\u1ee7 y\u1ebfu qua \u1ed1ng th\u1eadn. \u1eda ng\u01b0\u1eddi c\u00f3 ch\u1ee9c n\u0103ng th\u1eadn b\u00ecnh th\u01b0\u1eddng, tr\u00ean 95% li\u1ec1u h\u1ea5p thu \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft v\u00e0o n\u01b0\u1edbc ti\u1ec3u trong 24 gi\u1edd; kho\u1ea3ng 40 &#8211; 50% thu\u1ed1c b\u00e0i ti\u1ebft v\u00e0o n\u01b0\u1edbc ti\u1ec3u l\u00e0 captopril kh\u00f4ng chuy\u1ec3n h\u00f3a v\u00e0 s\u1ed1 c\u00f2n l\u1ea1i ch\u1ee7 y\u1ebfu l\u00e0 captopril-cystein disulfid v\u00e0 dimercaptopril disulfid. \u1eda ng\u01b0\u1eddi kh\u1ecfe m\u1ea1nh, kho\u1ea3ng 20% li\u1ec1u \u0111\u01a1n captopril \u0111\u00e3 t\u00ecm th\u1ea5y trong ph\u00e2n trong 5 ng\u00e0y, l\u00e0 thu\u1ed1c kh\u00f4ng chuy\u1ec3n h\u00f3a.<\/p>\n<p>Captopril c\u00f3 th\u1ec3 lo\u1ea1i b\u1ecf b\u1eb1ng th\u1ea5m ph\u00e2n m\u00e1u<\/p>\n<p><strong>5.3 Gi\u1ea3i th\u00edch: <\/strong><\/p>\n<p>Ch\u01b0a c\u00f3 th\u00f4ng tin. \u0110ang c\u1eadp nh\u1eadt.<\/p>\n<p><strong>5.4 Thay th\u1ebf thu\u1ed1c : <\/strong><\/p>\n<p>Ch\u01b0a c\u00f3 th\u00f4ng tin. \u0110ang c\u1eadp nh\u1eadt.<\/p>\n<p><strong><em>*L\u01b0u \u00fd:<\/em><\/strong><\/p>\n<p><strong><em>C\u00e1c th\u00f4ng tin v\u1ec1 thu\u1ed1c tr\u00ean Pharmog.com ch\u1ec9 mang t\u00ednh ch\u1ea5t tham kh\u1ea3o &#8211; Khi d\u00f9ng thu\u1ed1c c\u1ea7n tuy\u1ec7t \u0111\u1ed1i tu\u00e2n theo theo h\u01b0\u1edbng d\u1eabn c\u1ee7a B\u00e1c s\u0129 <\/em><\/strong><\/p>\n<p><strong><em>Ch\u00fang t\u00f4i kh\u00f4ng ch\u1ecbu tr\u00e1ch nhi\u1ec7m v\u1ec1 b\u1ea5t c\u1ee9 h\u1eadu qu\u1ea3 n\u00e0o x\u1ea3y ra do t\u1ef1 \u00fd d\u00f9ng thu\u1ed1c d\u1ef1a theo c\u00e1c th\u00f4ng tin tr\u00ean Pharmog.com<\/em><\/strong><\/p>\n<p><script src=\"https:\/\/pagead2.googlesyndication.com\/pagead\/js\/adsbygoogle.js?client=ca-pub-5528370293090692\" async=\"\" crossorigin=\"anonymous\"><\/script><ins class=\"adsbygoogle\" style=\"display: block; text-align: center;\" data-ad-layout=\"in-article\" data-ad-format=\"fluid\" data-ad-client=\"ca-pub-5528370293090692\" data-ad-slot=\"8909623906\"><\/ins><script> (adsbygoogle = window.adsbygoogle || []).push({}); <\/script><\/p>\n<p><strong>6. Ph\u1ea7n th\u00f4ng tin k\u00e8m theo c\u1ee7a thu\u1ed1c:<\/strong><\/p>\n<p><strong>6.1. Danh m\u1ee5c t\u00e1 d\u01b0\u1ee3c:<\/strong><\/p>\n<p>Manitol, povidon K30, acid stearic, croscarmellose natri, talc v\u1eeba \u0111\u1ee7 1 vi\u00ean..<\/p>\n<p><strong>6.2. T\u01b0\u01a1ng k\u1ef5 :<\/strong><\/p>\n<p>Kh\u00f4ng \u00e1p d\u1ee5ng.<\/p>\n<p><strong>6.3. B\u1ea3o qu\u1ea3n: <\/strong><\/p>\n<p>N\u01a1i kh\u00f4, tr\u00e1nh \u00e1nh s\u00e1ng, nhi\u1ec7t \u0111\u1ed9 d\u01b0\u1edbi 30\u00b0C.<\/p>\n<p><strong>6.4. Th\u00f4ng tin kh\u00e1c :<\/strong><\/p>\n<p>Kh\u00f4ng c\u00f3.<\/p>\n<p><strong>6.5 T\u00e0i li\u1ec7u tham kh\u1ea3o:<\/strong><\/p>\n<p>D\u01b0\u1ee3c Th\u01b0 Qu\u1ed1c Gia Vi\u1ec7t Nam<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>1. T\u00ean ho\u1ea1t ch\u1ea5t v\u00e0 bi\u1ec7t d\u01b0\u1ee3c: Ho\u1ea1t ch\u1ea5t : Captopril Ph\u00e2n lo\u1ea1i: Thu\u1ed1c \u1ee9c ch\u1ebf men chuy\u1ec3n. Thu\u1ed1c \u0111i\u1ec1u tr\u1ecb t\u0103ng huy\u1ebft \u00e1p. Nh\u00f3m ph\u00e1p l\u00fd: Thu\u1ed1c k\u00ea \u0111\u01a1n ETC \u2013 (Ethical drugs, prescription drugs, Prescription only medicine) M\u00e3 ATC (Anatomical Therapeutic Chemical): C09AA01. Bi\u1ec7t d\u01b0\u1ee3c g\u1ed1c: Bi\u1ec7t d\u01b0\u1ee3c: TAGUAR H\u00e3ng s\u1ea3n xu\u1ea5t : [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":15142,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[419],"tags":[545],"class_list":["post-15141","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-biet-duoc","tag-captopril"],"_links":{"self":[{"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/posts\/15141","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/comments?post=15141"}],"version-history":[{"count":3,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/posts\/15141\/revisions"}],"predecessor-version":[{"id":51501,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/posts\/15141\/revisions\/51501"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/media\/15142"}],"wp:attachment":[{"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/media?parent=15141"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/categories?post=15141"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pharmog.com\/wp\/wp-json\/wp\/v2\/tags?post=15141"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}